宫衡 - 华东理工大学 - 生物工程学院

个人简介

江苏镇江人，博士、教授、硕士生导师。1985至89 年，于无锡轻工业学院(现改名江南大学),获发酵工程工学学士学位；并于1994在该校获发酵工程工学博士学位。1995年至今，在华东理工大学生物工程学院从事教学和科研工作，期间于2000年至02年于日本大阪大学生物工程国际交流中心进行博士后研究。教学方面，主讲课程《发酵工程》为国家精品课程。研究方面主要从事微生物产品的开发，实施的多项产品技术水平处于国内领先；其中生物法1,3-丙二醇生产技术建成了国内首套万吨级的产业化装置。

研究领域

1、发酵过程工程：结合微生物营养需求与产物代谢的特点，通过过程优化与放大，以实现大规模水平上发酵过程的稳定与高效。 2、应用分子生物学：利用生物信息学和现代分子生物学方法手段，研究微生物的代谢调节及产物合成的机制。 3、生物检测主要利用表面增强拉曼光谱（SRES）实现生物样品的快速检测。

近期论文

查看导师新发文章（温馨提示：请注意重名现象，建议点开原文通过作者单位确认）

1. Lin, J., Zhang, Y., Xu, D., Xiang, G., Jia, Z., Fu, S., and Gong, H., Deletion of poxB, pta, and ackA improves 1,3-propanediol production by Klebsiella pneumoniae. Appl Microbiol Biotechnol, 2016. 100(6): p. 2775-84. 2. Huang, Y., Gu, J., Xiang, G., Xu, J., Fu, S., and Gong, H. Detection of total protein in milk using phosphomolybdic acid-mediated surface-enhanced Raman spectroscopy. J. Raman Spectrosc., 2015. DOI: 10.1002/jrs.4812. 3. Jiang, X., Zhu, C., Lin, J., Li, J., Fu, S., and Gong, H. Vector promoters used in Klebsiella pneumoniae. Biotechnol Appl Biochem, 2015. DOI: 10.1002/bab.1423. 4. Li, M.M., Chen, J., Xu, J.J., Fu, S.L., and Gong, H., Determination of Lactose in Milk by Raman Spectroscopy. Analytical Letters, 2015. 48(8): p. 1333-1340. 5. Zhu, C., Jiang, X., Zhang, Y., Lin, J., Fu, S., and Gong, H., Improvement of 1,3-propanediol production in Klebsiella pneumoniae by moderate expression of puuC (encoding an aldehyde dehydrogenase). Biotechnol Lett, 2015. 37(9): p. 1783-90. 6. Cui, Y.L., Zhou, J.J., Gao, L.R., Zhu, C.Q., Jiang, X., Fu, S.L., and Gong, H., Utilization of excess NADH in 2,3-butanediol-deficient Klebsiella pneumoniae for 1,3-propanediol production. J Appl Microbiol, 2014. 117(3): p. 690-8. 7. Gao, L.R., Jiang, X., Fu, S.L., and Gong, H., In silico identification of potential virulence genes in 1,3-propanediol producer Klebsiella pneumonia. J Biotechnol, 2014. 189(10): p. 9-14. 8. Zhong, Z.H., Liu, L.F., Zhou, J.J., Gao, L.R., Xu, J.J., Fu, S.L., and H., G., Influences of 3-hydroxypropionaldehyde and lactate on the production of 1,3-propanediol by Klebsiella pneumoniae. Bioresources and Bioprocessing, 2014. 1(1). 9. 刘龙飞, 周佳佳, 崔毅力, 付水林, and 宫衡, 1, 3-丙二醇发酵过程中乳酸抑制的研究. 生物技术, 2014. 24(001): p. 92-96. 10. Xiang, G., Li, J., Duan, J., Shao, F., Xu, J., Fu, S., and Gong, H., Acceleration effect of amino acid supplementation on glycerol assimilation by Escherichia coli in minimal medium. Biotechnol Lett, 2013. 35(9): p. 1495-500. 11. Xu, J., Turner, J.W., Idso, M., Biryukov, S.V., Rognstad, L., Gong, H., Trainer, V.L., Wells, M.L., Strom, M.S., and Yu, Q., In situ strain-level detection and identification of Vibrio parahaemolyticus using surface-enhanced Raman spectroscopy. Anal Chem, 2013. 85(5): p. 2630-7. 12. 张书翠, 陈军, 周佳佳, 高黎荣, 付水林, and 宫衡, 环境及内源条件对克雷伯氏肺炎杆菌质粒消除的影响. 生物技术, 2013. 23(005): p. 69-73. 13. Zhang, L., Xu, J., Mi, L., Gong, H., Jiang, S., and Yu, Q., Multifunctional magnetic-plasmonic nanoparticles for fast concentration and sensitive detection of bacteria using SERS. Biosensors & Bioelectronics, 2012. 31(1): p. 130-6. 14. 陶冶, 周佳佳, 张书翠, 付水林, and 宫衡, S-腺苷甲硫氨酸合成酶的可溶性表达. 华东理工大学学报: 自然科学版, 2012. 38(005): p. 594-598. 15. Xu, J., Kvasnicka, P., Idso, M., Jordan, R.W., Gong, H., Homola, J., and Yu, Q., Understanding the effects of dielectric medium, substrate, and depth on electric fields and SERS of quasi-3D plasmonic nanostructures. Opt Express, 2011. 19(21): p. 20493-505. 16. Xu, J., Zhang, L., Gong, H., Homola, J., and Yu, Q., Tailoring plasmonic nanostructures for optimal SERS sensing of small molecules and large microorganisms. Small, 2011. 7(3): p. 371-6. 17. Xu, J.J., Guan, P., Kvasnicka, P., Gong, H., Homola, J., and Yu, Q.M., Light Transmission and Surface-Enhanced Raman Scattering of Quasi-3D Plasmonic Nanostructure Arrays with Deep and Shallow Fabry-Perot Nanocavities. Journal of Physical Chemistry C, 2011. 115(22): p. 10996-11002. 18. 莫隽颖, 陶冶, 周佳佳, 高黎荣, 付水林, and 宫衡, Red 重组系统在克雷伯氏肺炎杆菌中的应用研究. 化学与生物工程, 2011. 28(8): p. 63-66. 19. Yu, Q., Braswell, S., Christin, B., Xu, J., Wallace, P.M., Gong, H., and Kaminsky, D., Surface-enhanced Raman scattering on gold quasi-3D nanostructure and 2D nanohole arrays. Nanotechnology, 2010. 21(35): p. 355301.