个人简介
周林燕,女,博士,研究员。西南大学生命科学学院,淡水鱼类资源与生殖发育教育部重点实验室特聘教授。在鱼类性别决定与分化、生殖内分泌调控、内分泌干扰物质作用机制等领域有丰富的研究经验。承担国家自然科学基金委、教育部、重庆市自然科学基金委等多项项目。在Molecular & Cellular Endocrinology、Journal of Molecular Endocrinology、Endocrinology、BBRC等国外学术杂志发表SCI学术论文38篇;总影响因子约130,单篇最高引用次数80余次。
研究经历
2016-至今 西南大学 生命科学学院 研究员 博士生导师
2010-2015 西南大学 生命科学学院 特聘教授
2007.10-2008.03 日本国立基础生物学研究所 博士后
教育经历
2004.7-2007.09 日本国立基础生物学研究所 基础生物学 哲学博士
2001.9-2004.07 西南师范大学(现西南大学) 动物学 理学硕士
1997.9-2001.07 西南师范大学(现西南大学) 制药工程 工学学士
近期论文
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1. Zhou LY, Charkraborty T, Zhou Q, Nagahama Y and Zhang YG. Rspo1-activated signaling molecules are sufficient to induce ovarian differentiation in XY medaka (Oryzias latipes). Sci. Rep. 2016. 19; 6:19543.
2. Shaohua Sun, Jing Cai, Wenjing Tao, Limin Wu, Chakraborty Tapas, Linyan Zhou*, Deshou Wang*. Comparative Transcriptome Profiling and Characterization of Gene Expression for Ovarian Differentiation under RU486 Treatment. General and Comparative Endocrinology, 2018. (*,通讯作者)
3. Chakraborty T, Mohapatra S, Tobayama M, Ohta K, Ryu YW, Kazeto Y, Ohta K, Zhou L*, Nagahama Y, Matsubara T*. Hatching enzymes disrupt aberrant gonadal degeneration by the autophagy/apoptosis cell fate decision. Sci Rep. 2017 9;7(1):3183. (*,通讯作者)
4. Wu L, Yang P, Luo F, Wang D*, Zhou L*. R-spondin1 signaling pathway is required for both the ovarian and testicular development in a teleosts, Nile tilapia (Oreochromis niloticus).Gen Comp Endocrinol. 2016. 1;230-231:177-85. (*,通讯作者)
5. Wu L, Wu F, Xie L, Wang D*, Zhou L*. Synergistic role of β-catenin1 and 2 in ovarian differentiation and maintenance of female pathway in Nile tilapia. Mol Cell Endocrinol. 2016. 15;427:33-44. (*,通讯作者)
6. Zhou L, Luo F, Fang X, Charkraborty T, Wu L, Wei J, Wang D*. Blockage of progestin physiology disrupts ovarian differentiation in XX Nile tilapia (Oreochromis niloticus). Biochem Biophys Res Commun. 2016. 22;473(1):29-34.
7. Qiu YX, Sun SH, Charkraborty T, Wu LM, Sun LN, Wei J, Nagahama Y, Wang DS*, Zhou LY*. Figla favors ovarian differentiation by antagonizing spermatogenesis in a teleosts, Nile tilapia (Oreochromis niloticus). Plos One, 2015. 20;10(4):e0123900. (*,通讯作者)
8. Yu# XG, Wu# LM, Xie L, Yang SJ, Charkraborty T, Shi HJ, Wang DS*, Zhou LY* . Characterization of two duplicated StAR genes in a teleost, Nile tilapia (Oreochromis niloticus). Molecular and Cellular Endocrinology, 2014. 5;392(1-2):152-62. (*,通讯作者)
9. Gang Liu, Feng Luo, Qiang Song, Limin Wu, Yongxiu Qiu, Hongjuan Shi, Deshou Wang*, Linyan Zhou*. Blocking of Progestin Action Disrupts Spermatogenesis in Nile tilapia (Oreochromis niloticus). Journal of Molecular Endocrinology, 2014. 53(1):57-70. (*,通讯作者)
10. Tao W#, Yuan J#, Zhou L#, Sun L#, Sun Y, Yang S, Li M, Zeng S, Huang B, Wang D*. Characterization of gonadal transcriptomes from Nile tilapia (Oreochromis niloticus) reveals differentially expressed genes. PLoS One. 2013. 3;8(5):e63604. (#:共同第一作者)
11. Zhou L, Charkraborty T, Yu X, Wu L, Liu G, Mohapatra S, Wang D*, Nagahama Y*. R-spondins are involved in the ovarian differentiation in a teleost, medaka (Oryzias latipes). BMC Dev Biol. 2012.12:36.
12. Sun YL, Zeng S, Ye K, Yang C, Li MH, Huang BF, Sun LN, Zhou LY*, Wang DS*. Involvement of FGF9/16/20 subfamily in female germ cell development of the Nile tilapia, Oreochromis niloticus. Fish Physiol Biochem. 2012. 38(5):1427-1439. (*,通讯作者)
13. Zhou LY, Wang DS, Kobayashi T, Yano A, Paul-Prasanth B, Suzuki A, Sakai F, Nagahama Y. A novel type of P450c17 lacking the lyase activity is responsible for C21-steroid biosynthesis in the fish ovary and head kidney. Endocrinology, 2007.148(9):4282-91;
14. Zhou LY, Wang DS, Shibata Yasushi, Paul-Prasanth B, Suzuki A, Nagahama Y. Characterization, expression and transcriptional regulation of P450c17-I and -II in the medaka. Biochem Biophys Res Commun 2007. 362(3):619-25.
15. Zhou LY, Wang DS, Senthilkumaran B, Yoshikuni M, Shibata Y, Kobayashi T, Sudhakumari CC, Nagahama Y. Cloning, expression and characterization of three types of 17beta-hydroxysteroid dehydrogenases from the Nile tilapia, Oreochromis niloticus. J Mol Endocrinol 2005. 35:103-116.