个人简介
李礼,博士,男,生于1981年9月。西南大学生命科学学院研究员、博士生导师,重庆市青年拔尖人才、重庆市“巴渝学者”特聘教授。
个人简历:
2000.09-2005.06 复旦大学公共卫生学院 学士学位
2007.01-2011.05 香港科技大学生物化学系 博士学位
2011.05-2012.02 香港科技大学生物化学系 博士后
2012.02-2013.06 西南大学生命科学学院 特聘教授
2013.06-至今 西南大学生命科学学院 研究员
个人荣誉:
1)2015年入选重庆市青年拔尖人才
2)2015年获聘为重庆市“巴渝学者”特聘教授
3)2014年入选重庆市高等学校青年骨干教师资助计划
4)2012年度香港科技大学理学院最佳毕业论文奖
近期论文
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1. Zhao F, Shi Y, Huang Y, Zhan Y, Zhou L, Li Y, Wan Y, Li H, Huang H, Ruan H, Luo L, Li L*. (2017) Irf8 regulates the progression of myeloproliferative neoplasm (MPN)-like syndrome via Mertk signaling in zebrafish. Leukemia. 10.1038/leu.2017.189. (IF=11.7)
2. Yu T, Guo W, Tian Y, Xu J, Chen J, Li L, Wen Z* (2017) Distinct regulatory networks control the development of macrophages of different origins in zebrafish. Blood 129(4):509-519. (IF=13.1)
3. Hou Y, Sheng Z, Mao X, Li C, Chen J, Zhang J, Huang H, Ruan H, Luo L, Li L*. (2016) Systemic inoculation of Escherichia coli causes emergency myelopoiesis in zebrafish larval caudal hematopoietic tissue. Sci Rep. 6:36853. (IF=5.2)
4. Jin H, Huang Z, Chi Y, Wu M, Zhou R, Zhao L, Xu J, Zhen F, Lan Y, Li L, Zhang W, Wen Z*, Zhang Y*. (2016) cMyb acts in parallel and cooperatively with Cebp1 to regulate neutrophil maturation in zebrafish. Blood 128(3):415-26. (IF=13.1)
5. Liu C, Wu C, Yang Q, Gao J, Li L, Yang D, Luo L*. (2016) Macrophages Mediate the Repair of Brain Vascular Rupture through Direct Physical Adhesion and Mechanical Traction. Immunity. 17;44(5):1162-76. (IF=22.8)
6. Chen J, He J, Li L, Yang D, Luo L*. (2016) Cyp2aa9 regulates haematopoietic stem cell development in zebrafish. Sci Rep. 6:26608. (IF=5.2)
7. Jia X, Ma K, Xu T, Gao L, Wu S, Fu C, Zhang W, Wang Z, Liu K, Dong M, Jing C, Ren C, Dong Z, Chen Y, Jin Y, Huang Q, Chang X, Deng M, Li L, Luo L, Zhu J, Dang Y, Chang H, Zon L, Zhou Y, Chen S, Pan W*. (2015) Mutation of kri1l causes definitive hematopoiesis failure via PERK-dependent excessive autophagy induction. Cell Res. 25(8):946-962. (IF=12.43)
8. Jiang F, Chen J, Ma X, Huang C, Zhu S, Wang F, Li L, Luo L, Ruan H*, Huang H*.(2015) Analysis of mutants from a genetic screening reveals the control of intestine and liver development by many common genes in zebrafish. Biochem Biophys Res Commun. 460(3):838-844.
9. Shi W, Fang Z, Li L, Luo L*. Using zebrafish as the model organism to understand organ regeneration. (2015) Sci China Life Sci. 58(4): 343-351.
10. Shi Y, Zhang Y, Zhao F, Ruan H, Huang H, Luo L, Li L*. (2014) Acetylcholine serves as a derepressor in Loperamide-induced Opioid-Induced Bowel Dysfunction (OIBD) in zebrafish. Sci Rep. Jul 7; 4:5602. (IF=5.2)
11. Yan B, Han P, Pan L, Lu W, Xiong J, Zhang M, Zhang W, Li L*, Wen Z*.(2014) Il-1 beta and Reactive Oxygen Species Differentially Regulate Neutrophil Directional Migration and Basal Random Motility in a Zebrafish Injury-Induced Inflammation. The Journal of Immunology. 192 (12): 5998-6008. (IF=4.9) (*co-corresponding author)
12. Sun J, Liu W, Li L, Chen J, Wu M, Zhang Y, Leung A, Zhang W*, Wen Z*, Liao W*. Suppression of Pu.1 function results in expanded myelopoiesis in zebrafish. (2013) Leukemia. 27(9):1913-1917. (IF=11.7)
13. Zeng Y, Xu J, Li D, Li L, Wen Z, Qu J *. (2012) Label-free in vivo flow cytometry in zebrafish using two-photon autofluorescence imaging. Optics Letters. 37(13):2490-2492.
14. Li L, Yan B, Shi Y, Zhang W, Wen Z*. (2012) Live Imaging Reveals Differing Roles of Macrophages and Neutrophils during Zebrafish Tail Fin Regeneration. Journal of Biological Chemistry. 287 (30): 25353-25360 (IF=4.5)
15. Jin H, Li L, Xu J, Zhen F, Zhu L, Liu P, Zhang M, Zhang W, Wen Z*. (2012) Runx1 regulates embryonic myeloid fate choice in zebrafish through a negative feedback loop inhibiting Pu.1 expression. Blood. 119 (22):5239-5249 (IF=13.1)
16. Li L, Jin H, Xu J, Shi Y, Wen Z*. (2011) Irf8 regulates macrophage versus neutrophil fate during zebrafish primitive myelopoiesis. Blood. 117(4): 1359-1369 (IF=13.1)
17. Zhang Y, Jin H, Li L, Qin X, Wen Z*. (2011) cMyb regulates hematopoietic stem/progenitor cell mobilization during zebrafish hematopoiesis. Blood. 118 (15): 4093-4101. (IF=13.1)