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个人简介

叶小利,女,博士,教授,博士生导师。2011.2-2011.8在美国Texas A&M University访问学习, 2011.11-2012.11在美国The Johns Hopkins University School of Medicine访学。

研究领域

主要从事高血脂、肥胖等代谢性疾病及癌症方面的新药、保健品及食品研发。

近期论文

查看导师新发文章 (温馨提示:请注意重名现象,建议点开原文通过作者单位确认)

1 Fang-Ni Chai, Jiang Zhang, Hong-Mei Xiang, He-Shan Xu, Yuan-Feng Li, Wen-Yu Ma, Xue-Gang Li, Xiao-Li Ye*. Protective effect of Coptisine from Rhizoma Coptidis on LPS/D-GalN-induced acute liver failure in mice through up-regulating expression of miR-122. Biomedicine & Pharmacotherapy, 2018, 98: 180-190. 2 Yubo Xiao, Cheng Tian, Tao Huang, Bing Han, Meimei Wang, Hang Ma, Zhaoxing Li, Xiaoli Ye*, Xuegang Li*. 8-Cetylberberine inhibits growth of lung cancer in vitro and in vivo. Life Sciences, 2018, 1: 259-269 3 Kai He, Hang Ma, Heshan Xu, Zongyao Zou, Min Feng, Xuegang Li*, Xiaoli Ye*. Anti-hyperlipidemic effects of Rhizoma Coptidis alkaloids are achieved through modulation of the enterohepatic circulation of bile acids and cross-talk between the gut microbiota and the liver. Journal of Functional Foods. 2017,35:205-215. 4 Tao Huang, Yubo Xiao, Lin Yi, Ling Li, Meimei Wang, Cheng Tian, Hang Ma, Kai He, Yue Wang, Bing Han, Xiaoli Ye*, and Xuegang Li*. Coptisine from Rhizoma Coptidis Suppresses HCT-116 Cells-related Tumor Growth in vitro and in vivo. Scientific Reports, 2017, 7:38524 | DOI: 10.1038/ 5 Min Feng, Zongyao Zou, Xia Zhou, Yinran Hu, Hang Ma, Yubo Xiao , Xuegang Li*, Xiaoli Ye*. Comparative effect of berberine and its derivative 8-cetylberberine on attenuating atherosclerosis in ApoE?/? mice. International Immunopharmacology, 2017, 43:195-202 6 Min Feng, Shu-Zhen Kong, Zhen-Xu Wang, Kai He, Zong-Yao Zou, Rin-Ran, Hu, Hang Ma, Xue-Gang Li*, Xiao-Li Ye*. The protective effect of coptisine on experimental atherosclerosis ApoE -/- mice is mediated by MAPK/NF-k B-dependent pathway. Biomedicine & Pharmacotherapy, 2017, 93: 721-729 7 Kai He, Yinran Hu, Hang Ma, Zongyao Zou, Yubo Xiao, Yong Yang, Min Feng, Xuegang Li*, Xiaoli Ye*. Rhizoma Coptidis alkaloids alleviate hyperlipidemia in B6 mice by modulating gut microbiota and bile acid pathways. Biochimica et Biophysica Acta- -molecular basis of disease, 2016, 1862: 1696–1709 8 Kai He, Shanghua Song, Zongyao Zou, Min Feng, Dezhen Wang, Yanzhi Wang, Xuegang Li* and Xiaoli Ye*. The Hypoglycemic and Synergistic Effect of Loganin, Morroniside, and Ursolic Acid Isolated from the Fruits of Cornus officinalis. Phytother Res. 2016, 30 (2):283-91. 9 Kai He, Shuming Kou, Zongyao Zou, Yinran Hu, Min Feng, Bin Han, Xuegang Li*, Xiaoli Ye*. Hypolipidemic Effects of Alkaloids from Rhizoma Coptidis in Diet-Induced Hyperlipidemic Hamsters. Planta Medica, 2016, 82:1-9 10. Zongyao Zou, Yin-RanHu, HangMa, MinFeng, XuegangLi*, Xiao-Li Ye*. Epiberberine reduces serum cholesterol in diet-induced dyslipidemia Syrian golden hamsters via net work pathways involving cholesterol metabolism. European Journal of Pharmacology, 2016, 774:1–9 11. Shuming Kou, Bing Han, Yue Wang, Tao Huang, Kai He, Yulong Han, Xia Zhou, Xiaoli Ye*, Xuegang Li*. Synergetic cholesterol-lowering effects of main alkaloids from Rhizoma Coptidis in HepG2 cells and hypercholesterolemia hamsters. Life Science, 2016, 151, 50-60 12. Ling Li, Tao Huang, Cheng Tian, Yubo Xiao, Shuming Kou, Xia Zhou, Shanshan Liu, Xiaoli Ye*, Xuegang Li*. Defensive effect of Phellodendrine against AAPH-induced oxidative stress through regulating AKT / NF-kB pathway in zebrafish embryo. Life Science, 2016, 157: 97-106 13. Yue Wang, Yulong Han, Fangni Chai, Hongmei Xiang, Tao Huang,Shuming Kou , Bing Han, Xiaobao Gong, Xiaoli Ye*, Xuegang Li*. The antihypercholesterolemic effect of columbamine from Rhizoma Coptidis in HFHC-diet induced hamsters through HNF-4α/FTF-mediated CYP7A1 activation. Fitoterapia, 2016, 2016, 115: 111-121 14. Kai He, Zongyao Zou, Yinran Hu, Yong Yang,Yubo Xiao, Pincao Gao, Xuegang Li, Xiaoli Ye*. Purification of a-glucosidase from mouse intestine by countercurrent chromatography coupled with a reverse micelle solvent system. Journal of Separation Science, 2016, 39: 703-708. 15. Min Feng, Zongyao Zou, Xia Zhouc, Yinran Hu, Hang Ma, Yubo Xiao , Xuegang Li*, Xiaoli Ye*. Comparative effect of berberine and its derivative 8-cetylberberine on attenuating atherosclerosis in ApoE?/? mice. International Immunopharmacology, 2016, 43: 195–202 16. Zongyao Zou, Yinran Hu, Hang Ma, Yanzhi Wang, Kai He, Shuang Xia, Hao Wu, Dongfang Xue, Xuegang Li*, Xiaoli Ye*. Coptisine attenuates obesity-related inflammation through LPS/TLR-4-mediated signaling pathway in Syrian golden hamsters. Fitoterapia, 2015, 105(9): 139–146. 17. Hao Wu, Kai He, YanZhi Wang, DongFang Xue, Na Ning, Zongyao Zou, Xiaoli Ye*, Xuegang Li, DeZhen Wang, Jie Pang The antihypercholesterolemic effect of jatrorrhizine isolated from Rhizoma Coptidis. Phytomedicine, 2014, 21 : 1373–1381

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