个人简介
学习工作经历：
2015/07– 至 今， 华中师范大学，生命科学学院，副教授
2012/07–2015/07，华中师范大学，生命科学学院，讲师
2012/06–2014/05，多伦多大学，SGC 研究所，博士后
2010/03–2012/03，多伦多大学，SGC 研究所，博士联合培养
2007/09–2012/06，华中师范大学，生命科学学院，博士
2002/09–2006/06，鲁东大学，生命科学学院，学士
科研经历：
1. 国家自然科学基金面上项目，编号：31770834，MIS复合物介导酵母孢子形成的分子机制研究，2018/01 - 2021/12，主持
2. 湖北省自然科学基金面上项目，编号：2017CFB513，生物标记物hNGAL多价高灵敏免疫检测抗体的研发，2017/01-2018/12，主持
3. 国家自然科学基金面上项目，编号：31470171，蓝细菌TonB-ExbB-ExbD依赖的铁吸收机制研究，2016/01 - 2019/12，主要参与
4. 国家自然科学基金面上项目，编号：31472052，豆野螟嗅觉识别的分子机理研究，2016/01 - 2019/12，主要参与
5. 国家自然科学基金青年项目，编号：31300629，WDR82介导Setd1A复合物定位于基因转录起始位点进而调控基因转录的分子机理研究，2014/01-2017/12，主持
6. 湖北省自然科学基金面上项目，编号：2013CFB206，2013/01-2014/12，WDR82识别底物的分子机理研究，主持
研究领域
结合分子生物学、生物化学、生物物理学和X射线衍射等技术，主要从事表观遗传学相关蛋白的结构与功能研究，并基于相关蛋白进行靶向药物设计及筛选。
近期论文
查看导师新发文章
（温馨提示：请注意重名现象，建议点开原文通过作者单位确认）
1. Ke Liu1,3,4, Chao Xu1,3,4, Ming Lei1,3,4, Ally Yang2, Peter Loppnau1, Timothy R Hughes2, and Jinrong Min1, 3 *. Structural basis for the ability of MBD domains to bind methyl-CG and TG sites in DNA, Journal of Biological Chemistry, 2018, doi: 10.1074/jbc.RA118.001785.
2. Chao Xu, Ke Liu (co-first author), Ming Lei, Ally Yang,Yanjun Li, Timothy R. Hughes, Jinrong Min, DNA Sequence Recognition of Human CXXC Domains and Their Structural Determinants, Structure, 2018, 26(1):85-95.
3. Heng Zhanga,1, Ke Liu (co-first author)a,1, Natsuko Izumib,1, Haiming Huangc, Deqiang Dingd, Zuyao Nie, Sachdev S. Sidhuc, Chen Chend, Yukihide Tomarib,f,2, and Jinrong Mina,g,2, Structural basis for arginine methylation-independent recognition of PIWIL1 by TDRD2, Proc Natl Acad Sci U S A (PNAS), 2017, 114(47):12483-12488.
4. Ke Liu*, Yumin Ding, Weiyuan Ye, Yanli Liu, Jihong Yang, Jinlin Liu and Chao Qi*, Structural and Functional Characterization of the Proteins Responsible for N6-Methyladenosine Modification and Recognition, Current Protein and Peptide Science, 2016, 17, 306-318.
5. Ke Liu, Yanli Liu, Johnathan L. Lau, Jinrong Min. Epigenetic targets and drug discovery Part 2: Histone demethylation and DNA methylation. Pharmacology & Therapeutics, 2015, 151, 121–140.
6. Chao Xu, Xiao Wang, Ke Liu (co-first author), Ian A Roundtree, Wolfram Tempel, Yanjun Li, Zhike Lu, Chuan He, Jinrong Min. Structural basis for selective binding of m6A RNA by the YTHDC1 YTH domain. Nature Chemical Biology, 2014, 10(11), 927-929.
7. Yanli Liu, Ke Liu (co-first author), Su Qin, Chao Xu, Jinrong Min. Epigenetic targets and drug discovery Part 1: histone methylation. Pharmacology & Therapeutics, 2014, 143(3), 275-294.
8. Chao Xu, Ke Liu (co-first author), Wolfram Tempel, Marina Demetriades, WeiShen Aik, Christopher J. Schofield, Jinrong Min. Structures of human ALKBH5 demethylase reveal a unique binding mode for specific single stranded m6A RNA demethylation. Journal of Biological Chemistry, 2014, 289(25), 17299-17311.
9. Su Qin, Yanli Liu, Wolfram Tempel, Mohammad S. Eram, Chuanbing Bian, Ke Liu, Guillermo Senisterra, Lissete Crombet, Masoud Vedadi & Jinrong Min*.Structural basis for histone mimicry and hijacking of host proteins by influenza virus protein NS1. Nature Communication, 2014, doi: 10.1038/ ncomms 4952.
10. Ke Liu, Chen Chen, Yahong Guo, Robert Lam, Chuanbing Bian, Chao Xu, Dorothy Y. Zhao, Jing Jin, Farrell MacKenzie, Tony Pawson, Jinrong Min. Structural basis for recognition of arginine methylated Piwi proteins by the extended Tudor domain. Proceedings of the National Academy of Sciences of the United States of America (PNAS), 2010, 107, 18398-18403.
11. Ke Liu, Yahong Guo, Haiping Liu, Chuanbing Bian, Robert Lam, Yongsong Liu, Farrell Mackenzie, Luis Alejandro Rojas, Danny Reinberg, Mark T. Bedford, Rui-Ming Xu, Jinrong Min. Crystal Structure of TDRD3 and methyl-arginine binding characterization of TDRD3, SMN and SPF30 [J]. PLoS One, 2012, 7(2), e30375
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