个人简介
1974.01.19,博士,副教授
学习工作经历
2002/09–2005/07,华中科技大学同济医学院,病理学与病理生理学,博士
1999/09–2002/06,华中科技大学同济医学院,病理学与病理生理学,硕士
工作经历
2008/06-至今,华中师范大学,生命科学学院,副教授
2005/07-2008/06,华中师范大学,生命科学学院,讲师
1997/07-1999/07,赤壁市人民医院,内科,住院医
研究领域
1.海马依赖性学习与机制的细胞分子机制的研究2. 蛋白质降解障碍在脑认知缺陷中的作用和机制研究
近期论文
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1. Yu Quntao(#), Zhang Hongmao(#), Li Yuan, Liu Chao, Wang Shaohui(*), LiaoXiaome(*), UCH-L1 Inhibition Suppresses tau Aggresome Formation during Proteasomal Impairment. Molecular Neurobiology, 2018, 55:3812–3821.
2. Cheng Liang(#), Wang Shaohui (#), Kang Peng, Liao Xiaomei (*), Long-Term Impairment of Sound Processing in the Auditory Midbrain by Daily Short-Term Exposure to Moderate Noise. Neural Plasticity, 2017, DOI: 10.1155/2017/3026749.
3. Xie Min(#), Li Yuan(#), Wang Shaohui(#), Yu Quntao, Meng Xin, Liao Xiaomei(*),The Involvement of NR2B and tau Protein in MG132-Induced CREB Dephosphorylation. Journal of Molecular Neuroscience, 2017, 62:154–162.
4. Wang shaohui(#), Zhang Pengyan(#), Liu Ruifang, Li Yuan, Liu Chao and Liao Xiaomei (*), DEHP Plasticizer Alters Synaptic Proteins Via Peroxidation, Toxicol. Res., 2017,6: 89-97.
5. Xie Min(#), Han Yun(#), Yu Quntao, Wang Xia, Wang Shaohui, Liao Xiaomei(*), UCH-L1 inhibition decreases the microtubule-binding function of tau protein, Journal of Alzheimer’s Disease , 2016,49:353 -363.
6. Cheng Liang(#), Wang Shaohui (#), Huang Yun, Liao Xiaomei (*), The hippocampus may be more susceptible to environmental noise than the auditory, Hearing Research, 2016 , 333: 93-97.
7. Tang Jiaqi(#), Yuan Ye(#),Wei Chenxi, Liao Xiaomei,Yuan Junlin,Nanberg Eewa, Zhang Yinping, Bornehag Carl-Gustaf(*), Yang Xu(*) , Neurobehavioral changes induced by di(2-ethylhexyl) phthalate and the protective effects of vitamin E in Kunming mice,Toxicology Research,2015,4: 1006-1015.
8. Xie Min(#), Shi Ruihong(#), Pan Ying(#), Zeng Tao, Chen Qicai, Wang Shaohui, Liao Xiaomei(*), Proteasome inhibition induced downregulation of Akt/GSK-3β pathway contributes to abnormality of tau in hippocampal slice, Molecular Neurobiology, 2014, 50: 888-895.
9. Xie Min(#), Wang Shaohui(#), Lu Zhimin, Pan Ying, Chen Qicai, Liao Xiaomei(*), UCH-L1 inhibition involved in CREB dephosphorylation in hippocampal slices, Journal of Molecular Neuroscience , 2014,53: 59-68.
10. Cheng Liang(#), Wang Shaohui(#), Jia Nan, Xie Min, Liao Xiaomei(*), Environmental stimulation influence the cognition of developing mice by inducing changes in oxidative and apoptosis status, Brain & Development , 2014,36: 51-56.
11. Wang Shaohui (#), Liao XiaoMei, Liu Dan, Hu Juan, Yin Yangyang, Wang Jianzhi(*), Zhu Lingqiang(*), NGF promotes long-term memory formation by activating poly (ADP-ribose) polymerase-1, Neuropharmacology, 2012, 63: 1085- 1092.
12. Cheng Liang(#), Wang Shaohui(#), Chen Qicai, Liao Xiaomei(*), Moderate noise induced cognition impairment of mice and its underlying mechanisms, Physiology & Behavior, 2011, 104: 981-988.
13. 谢敏(#),陈其才,廖晓梅(*), 泛素C末端水解酶L1对神经元的保护作用, 生物化学与生物物理进展,2010,37:1054-1058.
14. Ren Qingguo(#) , Liao Xiaomei(#) ,Wang Zefen, Qu Zhongshen, Wang Jianzhi(*), The involvement of glycogen synthase kinase-3 and protein phosphatase- 2A in lactacystin-induced tau accumulation,FEBS Letters, 2006,580: 2503- 2511.
15. Ren Qingguo(#), Liao Xiaomei(#), Chen Xiaoqian, Liu GongpPing, Wang Jianzhi(*),Effects of tau phosphorylation on proteasome activity, FEBS Letters, 2007, 581: 1521- 1528.