耿辉 - 华中师范大学 - 生命科学学院

个人简介

教育经历： 2003/9-2006/6，华中科技大学同济医学院，生物化学与分子生物学,获博士学位 1996/9-1999/6，同济医科大学，病原微生物学，硕士 1990/9-1995/6，泰山医学院，临床医学，学士工作经历： 2008/9-至今，华中师范大学，生命科学学院，副教授 2009/7-2010/7，瑞典Karolinska Insitute，访问学者 2006/9-2008/8，瑞典Lund大学，博士后 1999/7-2003/9，武汉市疾病控制中心，主治医师

研究领域

从事免疫性疾病发病机制方面的研究工作，主要研究自身抗原在类风湿性关节炎免疫疾病的发病机制。擅长利用Ⅱ型胶原蛋白和关节软骨寡聚基质蛋白诱发性关节炎动物模型研究探索类风湿性关节炎免疫发病机制。

近期论文

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1. Dandan Li, Jiali Yan,Li Wang, Yunze Zhang, Deli Liu,Geng H, Xiong L, 2016. Characterizationof the phthalate acid catabolic gene cluster in phthalate acid esterstransforming bacterium-Gordonia sp. Strain.InternationalBiodeterioration & Biodegradation,106:34-40. 2. Wang J, Yu J, Liu J,Yuan Y, Li N, He M, Qi T,Geng H, Xiong L, Liu D.Novel mutations inCYP51B from Penicillium digitatum involved in prochloraz resistance.JMicrobiol, 2014,52:762-770. 3.Geng Hui*, Kutty SelvaNandakumar, Li Xiong, Rui Jie, Jiahui Dong, Rikard Holmdahl, 2013. Incomplete BCell Tolerance to Cartilage Oligomeric Matrix Protein in Mice,Arthritis& Rheumatism, 65:2301-2309. 4.Geng Hui, Kutty SelvaNandakumar, Anna Pramhed, Anders Aspberg, Ragnar Mattsson, Rikard Holmdahl, 2012.Cartilage oligomeric matrix protein specific antibodies are pathogenic,ArthritisResearch & therapy, 14:R191. 5. Elhag OA, Hu Xao Jing, Zhang WeiYing, Xiong Li, Yuan Yong Ze, Deng Ling Fu, Liu De Li, Liu Ying Le,Geng Hui*, 2012. Reconstructed Adeno-Associated Virus with the Extracellular Domain ofMurine PD-1 Induces Antitumor Immunity,Asian Pacifc Journal of Cancer Prevention,2012,13:4031 -4035. 6. Han Rui, Zhang Jianhua, LiShuxiang, Cao Shufen,Geng Hui, Yuan Yongze, Xiao Wenjing, LiuShenghua, Liu Deli*, 2010. Homology modeling and screening of new14α-demethylase inhibitor (DMI) fungicides based on optimized expression ofCYP51 from Ustilago maydis in Escherichia coli,Journal of AgriculturalFood Chemistry, 58(24), 12810-12815. 7.Geng Hui,Stefan Carlsen,Kutty Selva Nandakumar, Rikard Holmdahl, Anders Aspberg, Oldberg Asperg, RagnarMattsson, 2008. Cartilage oligomeric matrix protein (COMP) deficiency promotesearly onset and the chronic development of collagen-induced arthritis,ArthritisResearch & therapy, 10:R134. (First author, SCI:4.45） 8.Geng Hui, Zhang Gui Mei,Li Dong, Zhang Hui, Yuan Ye, Zhu Han Gang, Xiao Han, Han Ling Fei, Feng ZuoHua, 2006. Soluble Form of T Cell Ig Mucin 3 Is an Inhibitory Molecule in T Cell-MediatedImmune Response,The Journal of Immunology, 176: 1411-1420. 9.Geng Hui, Zhang Gui Mei,Xiao Han, Yuan Ye, Li Dong, Zhang Hui, Qiu Hui, He Yu Fei, Feng ZH, 2006. HSP70vaccine in combination with gene therapy with plasmid DNA encoding sPD-1 overcomesimmune resistance and suppresses the progression of pulmonary metastaticmelanoma,International journal of Cancer, 118: 2657-2664. 10.揭瑞,董佳慧,韩冬,王瑞玲,韩魏巍,杜戎,耿辉, 2015.人源α-烯醇化酶B细胞表位鉴定及其与牙龈卟啉单胞菌烯醇化酶的交叉反应预测.中国免疫学杂志, 31:66-72.