个人简介
教育经历:
1987年9月-1991年7月 湖北大学 学士学位
2002年9月-2007年6月 武汉大学 博士学位
工作经历:
2007年7月至今 华中师范大学,生命科学学院,讲师,副教授
2014年3月-2015年3月 美国匹兹堡大学,医学院,访问学者
1991年7月-2002年8月 武钢程潮铁矿子弟中学 教师
荣誉或奖励
2016年6月 湖北省科学技术进步奖二等奖
2018年1月 2017年度英国皇家化学学会杰出评审专家
近期论文
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1. Duan JF, Kang J, Deng T, Yang X, Chen MQ*. 2018. Exposure to DBP and High Iodine Aggravates Autoimmune Thyroid Disease Through Increasing the Levels of IL-17 and Thyroid-Binding Globulin in Wistar Rats. Toxicological Sciences, 163(1):196–205.
2. Kang J, Duan JF, Song J, Luo C, Liu H, Li BZ, Yang X, Yu W*, Chen MQ*. 2018. Exposure to a Combination of Formaldehyde and DINP Aggravated Asthma-like Pathology through Oxidative Stress and NF-κB activation. Toxicology, 404–405: 49–58
3. Deng T, Zhang Y, Wu Y, Ma P, Duan JF, Qin W, Yang X, Chen MQ*. 2018. Dibutyl phthalate exposure aggravates type 2 diabetes by disrupting the insulin-mediated PI3K/AKT signaling pathway, Toxicology Letters, 290, 1-9.
4. Qin W, Deng T, Cui HY, Zhang Q, Liu XD, Yang Xu, Chen MQ*. 2018. Exposure to diisodecyl phthalate exacerbated Th2 and Th17-mediated asthma through aggravating oxidative stress and the activation of p38 MAPK. Food and Chemical Toxicology, 114:78-87.
5. Duan JF, Kang J, Qin W, Deng T, Liu H, Li BZ, Yu W, Gong SY, Yang X, Chen MQ*. 2018. Exposure to formaldehyde and diisononyl phthalate exacerbate Neuroinflammation through NF-κB activation in a mouse asthma model. Ecotoxicology and Environmental Safety, 163:356-364.
6. Kang J, Ding Y, Li BZ, Liu H, Yang X and Chen MQ *. 2017, TRPA1 mediated aggravation of allergic contact dermatitis induced by DINP and regulated by NF-κB activation. Sci.Rep.7, 43586; doi: 10.1038/srep43586.
7. Shen SP, Li JQ, You HH, Wu Z, Wu Y, Zhao Y, Zhu YQ, Guo Q, Li XX, Li R, Ma P, Yang X, Chen MQ *. 2017. Oral exposure to diisodecyl phthalate aggravates allergic dermatitis by oxidative stress and enhancement of thymic stromal lymphopoietin, Food and Chemical Toxicology, 99: 60-69
8. Kang J, Song J, Shen SP, Li BZ, Yang X and Chen MQ*. 2016. Diisononyl phthalate aggravates allergic dermatitis by activation of NF-κB, Oncotarget, 7(51): 85472-85482.
9. Yan B, Li JQ, Guo JH, Ma P, Wu Z, Ling ZH, Guo H, Hiroshi Y, Yanagi U, Yang X, Zhu SW *, Chen MQ *.2016.The toxic effects of indoor atmospheric fine particulate matter collected from allergic and non-allergic families in Wuhan on mouse peritoneal macrophages. Journal of Applied Toxicology, 36(4):596-608
10. Chen MQ, Sun F., Han L., Qu, ZX. 2016. Kaposi's sarcoma herpesvirus (KSHV) microRNA K12-1 functions as an oncogene by activating NF-κB/IL-6/STAT3 signaling. Oncotarget, 7(22), 33363-33373.
11. Zhu SW, Cai W, Yoshino H, Yanagi U, Hasegawa K, Kagi N, Chen MQ. 2015. Primary pollutants in schoolchildren's homes in Wuhan, China. Building and Environment, 93:41-53.
12. Min A, Liu FM, Yang X, Chen MQ*. 2014. Benzyl butyl phthalate exposure impairs learning and memory and attenuates neurotransmission and CREB phosphorylation in mice. Food and Chemical Toxicology,71: 81-89.
13. Zeng Q, Wei CX , Wu Y, Li K , Ding SM , Yuan JL , Yang X, Chen MQ *. 2013. Approach to distribution and accumulation of dibutyl phthalate in rats by immunoassay. Food and Chemical Toxicology, 56: 18-27
14. Chen MQ, Wei HB, Cao JW, Liu RJ, Wang YL, Zhen CY. 2007. Expression of Bacillus subtilis proBA genes and reduction of feedback inhibition of proline synthesis increases proline production and confers osmotolerance in transgenic Arabidopsis. Journal of Biochemistry and Molecular Biology, 40: 396-403.
15. Chen MQ, Cao JW, Zheng CY, Liu Q.2006. Directed evolution of an artificial bifunctional enzyme, γ-glutamyl kinase/γ-glutamyl phosphate reductase, for improved osmotic tolerance of Escherichia coli transformants. FEMS Microbiology Letters, 263: 41-47.