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个人简介

教育经历: 1975.9—1978.7 华中师范大学生物学 学士 1978.9—1981.7 华中师范大学化学系 进修 1996.9—1999.6 武汉大学生命科学院 博士 工作经历: 1978.8—1986.6 华中师范大学生科院 助教 1986.6—1993.6 华中师范大学生科院 讲师 1993.6—1998.12华中师范大学生科院 副教授 1998.12—. 华中师范大学生科院 教授 国外工作经历: 1986.9—1987.12美国俄亥俄州立大学生物化学系访问学者 1993.9—1995.4日本筑波大学应用生物化学系 访问学者 2000.8—2002.3日本筑波大学应用生物化学系 研究员 2002.4—2004.1日本神户大学遗传研究中心 研究员 荣誉或奖励: 2009年10月获湖北省教学成果一等奖(排名第二)湖北省教育厅 新世纪跨学科“化学生物学”人才培养模式与课程体系改革的研究与实践 2011年12月获湖北省自然科学三等奖(排名第一)湖北省政府 环境微生物功能酶降解机理与新型农残检测技术研究

研究领域

1.基因工程和应用酶学研究。主要从事细胞色素P450的分子生物学研究,包括真菌反硝化相关的P450nor作用机理和农药靶标酶CYP51的作用机理研究。 2.环境微生物研究。在环境治理方面,着重开展了微生物脱氮(反硝化)、有机磷农药降解机理的研究工作。

近期论文

查看导师新发文章 (温馨提示:请注意重名现象,建议点开原文通过作者单位确认)

1. NiuYH, Zhang TF, Zhu Yi, YuanYZ, Wang SQ, Liu J,Liu DL*.Isolationandcharacterizationofanovelmycovirusfrom Penicillium digitatum.Virology2016,494:15–22 2. ZhangJH, Zhao L, Zhang J, Han R, Li SX, Yuan YZ, Wan J, Xiao WJ andLiu DL*.Optimisedexpression and spectral analysis of the target enzyme CYP51 fromPenicilliumdigitatumwith possible new DMI fungicides. PestManag Sci. 2010, 66: 1344–1350 3. HanR, Zhang JH, Li SX, Cao SF, Geng H, Yuan YZ, Xiao WJ, Liu SH andLiu DL*.Homology Modeling and Screening of New 14a-DemethylaseInhibitor (DMI) Fungicides Based on Optimized Expression of CYP51 from Ustilagomaydis inEscherichia coli.J Agric Food Chem.2010,58, 12810–12816 4. LiWJ, Li Q,Liu DL*,and Ding MW* Synthesis, Fungicidal Activity,and Sterol 14α -Demethylase Binding Interaction of 2‑Azolyl-3,4-dihydroquinazolines onPenicilliumdigitatum.J Agric Food Chem.2013,61:1419-1426 5. WeiyingZhang, Yong Tang, Dan Du*, Jordan Smith, Charles Timchalk,Deli Liu*,Yuehe Lin*. Direct analysis of trichloropyridinol in human saliva using an Aunanoparticles-based immunochromatographic test strip for biomonitoring ofexposure to chlorpyrifos. Talanta2013,114:261-267 6. WeiyingZhang1,3, Xiaoxiao Ge2, Yong Tang2, Dan Du2,3,Deli Liu1*, Yuehe Lin3*.Nanoparticle-BasedImmunochromatographic Test Strip with Fluorescent Detector for Quantificationof Phosphorylated Acetycholinesterase: An Exposure Biomarker ofOrganophosphorous Agents. Analyst2013,138, 5431-5436 7. JingLiu, Yongze Yuan,Zhi Wu, Na Li, YuanleiChen, Tingting Qin, Hui Geng, Li Xiong,Deli Liu*A Novel SterolRegulatory Element-Binding Protein Gene ( sreA ) Identified in PenicilliumdigitatumIs Required for Prochloraz Resistance, Full Virulence anderg11(cyp51)Regulation.PLoS ONE2015, 10(2): e0117115. 8. JingLiu‡, Shengqiang Wang‡, Tingting Qin, Na Li,Yuhui Niu, DandanLi, Yongze Yuan, Hui Geng, Li Xiong, DeliLiu* Wholetranscriptome analysis ofPenicillium digitatumstrains treatmented withprochloraz reveals their drug-resistant mechanisms.BMCGenomics2015, 16:855 DOI:10.1186/s12864-015-2043-x 9. Zhi Wu.ShengqiangWang.Yongze Yuan.TingfuZhang.Jing Liu.DeliLiu*.A novel major facilitator superfamily transporter in Penicillium digitatum(PdMFS2) is required for prochloraz resistance, conidiation and full virulence.Biotechnol Lett2016,38:1349–1357 DOI10.1007/s10529-016-2113-4. 10. Dandan Li1,Jiali Yan1, Li Wang, Yunze Zhang,DeliLiu, Hui Geng, Li Xiong*. Characterization of the phthalate acidcatabolic gene cluster in phthalate acid esters transforming bacterium-Gordoniasp. Strain HS-NH1,International Biodeterioration & Biodegradation,2016,106:36-40. DOI: 10.1016/j.ibiod.2015.09.019. 11. Na Li12*, Yunze Zhang1*,Dandan Li1, Yuhui Niu1, Jing Liu1, Shuxiang Li1,Yongze Yuan1, Shuli Chen1, Hui Geng1,DeliLiu1**.Overexpression, homology modeling and coenzyme dockingstudies of the cytochrome P450nor2 fromCylindrocarpon tonkinense,MolecularBiology,2016,50(2):320–327. 12. LiN,*Li D.D*, Zhang Y.Z, Yuan Y.Z, Geng H, Xiong L and Liu D.L. Genome sequencingand systems biology analysis of a lipase-producing bacterial strain,Genet.Mol. Res.2016, 15(1): gmr.15017331 13. PanWang Yongze Yuan Qian Li Junzhong Yang Yongliang Zheng Muqing He Hui Geng LiXiongDeli Liu* Isolation and immobilization of new aerobic denitrifyingbacteria.InternationalBiodeterioration & Biodegradation2013,76:12-17 14. XueYang, Can Zhang, Zhen He, Xiaojing Hu, Jia Guo, Qiu Zhong, Jinlong Wang, LiXiong*,Deli Liu. Isolation and characterization of two n-butyl benzylphthalate degrading bacteria,International Biodeterioration &Biodegradation.2013,76:8-11 15. Cao XF,Hu M, Zhang J, Li F, Yang YH,Liu DL*,Liu SH*.Determination of StereoselectiveInteraction between Enantiomers of Chiral γ-Aryl-1H-1,2,4-triazole Derivativesand Penicillium digitatum.J. Agric. Food Chem.2009, 57,6914–6919 16. Du D*,Ye XP, Zhang JD, Zeng Y, Tu HY, Zhang AD,Liu DL*.Stripping voltammetricanalysis of organophosphate pesticides based on solid-phase extraction atzirconia nanoparticles modified electrode.Electrochem. Commun.2008, 10, 686-690. 17. Dan Du*,Xiuping Ye, Jiande Zhang,Deli liu*(刘德立).Cathodicelectrochemical analysis of methyl parathion at bismuth-film-modified glassycarbon electrode.Electrochimica Acta2008, 53,4478-4484. 18. DanDu, Wenjuan Chen,Weiying Zhang,Deli Liu Haibing Li, YueheLin. Covalent coupling of organophosphorus hydrolase loaded quantum dots tocarbon nanotube/Au nanocomposite for enhanced detection of methyl parathion.Biosens. Bioelectron2010,25:1370-1375 19. Weiying Zhang,Jiawang Ding, Yuehua Qin,Deli Liu*and Dan Du* One-Step Electrochemically Deposited GoldNanoparticles Interface Grafted with Avidin for Acetylcholinesterase BiosensorDesign. Journal of Nanoscience and Nanotechnology2010,10, 1–7. 20. Qingye Zhang§†‡, Ding Li§†,Pei Wei†, Jie Zhang†, Jian Wan*†, Yangliang Ren†, Zhigang Chen†,Deli Liu†,Ziniu Yu†‡ and Lingling Feng*† Structure-Based Rational Screening of Novel HitCompounds with Structural Diversity for Cytochrome P450 Sterol 14α-Demethylase from Penicilliumdigitatum J. Chem. Inf. Model.,2010, 50 (2),pp 317–325

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