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个人简介

高翔,副教授,博士生导师,东师仿吾青苗学者,主要从事经济植物重要农艺性状转录调控研究。2010年毕业于东北师范大学生命科学学院,获细胞生物学博士学位;2016年12月至2017年12月在加拿大英属哥伦毕业大学植物系开展访学研究。目前,主持国家重点研发计划子课题1项、国家自然科学基金青年项目1项、吉林省科技厅项目3项,参与科技部国际合作项目和国家自然科学基金面上项目多项;参编教材2部;参与培育多个花卉新品种,获得发明专利2项;以第2完成人获吉林省科技进步一等奖和二等奖各1项。近5年,在J Exp Bot等杂志发表SCI论文26篇,其中通讯作者19篇。 Front. Plant Sci杂志Reviewer Editor,Journal of Experimental Botany等杂志审稿人,国家自然科学基金网评审稿人。

研究领域

经济植物重要农艺性状调控网络解析及其进化意义探究方向 (1)依托课题组长期的研究优势,进一步解析观赏花卉香雪兰花朵多种重要农艺性状的转录调控网络,建立香雪兰瞬时及稳定遗传转化体系。首先,筛选并验证控制除花色苷以外的其他类黄酮物质(如黄酮醇和原花青素)生物合成的转录因子基因,并解析相关的调控网络。其次,筛选与控制香雪兰花香形成相关的挥发性萜类合酶基因表达的转录因子基因的功能。最后,厘清在香雪兰花朵发育过程中控制上述各种次生代谢物质合成的转录调控网络之间的复杂的交互作用关系。 (2)基于香雪兰花色苷转录调控模型研究基础,对比其他被子植物,包括基础双子叶植物(耧斗菜和/荷花),单子叶植物(香雪兰和/蝴蝶兰),核心双子叶植物(大豆和/烟草)。揭示MBW复合物中MYB转录因子在被子植物进化过程中的进化机制。 (3)依托承担的国家科技计划项目国家重点研发计划项目,重点筛选控制大豆和番茄异黄酮、花色苷和原花青素等次生代谢物质合成的MYB和MADS-box等转录因子基因,解析它们参与的转录调控网络。 (4)与加拿大英属哥伦比亚大学(UBC)植物系的Quentin Cronk教授合作,探究花色和花香等花朵性状影响植物传粉者选择行为的分子机制,揭示花色和花香性状的生态和进化意义。

近期论文

查看导师新发文章 (温馨提示:请注意重名现象,建议点开原文通过作者单位确认)

(1)Li Y, Shan X, Zhou L, Gao R,Yang S, Wang S, Wang L and Gao X(高翔)* (2019) The R2R3-MYB Factor FhMYB5 From Freesia hybrida Contributes to the Regulation of Anthocyanin and Proanthocyanidin Biosynthesis. Front. Plant Sci. 9:1935. (2)Jing Chen, Baofeng Liu, Zhongzhou Yang, Jiao Qu, Hongwei Xun, Runzhi Dou, Xiang Gao(高翔)*, and Li Wang*, Phenotypic, transcriptional, physiological and metabolic responses to carbon nanodots exposure in Arabidopsis thaliana (L.),2018, Environ. Sci.: Nano, 2018, 5, 2672 (3)Chen J, Dou R, Yang Z, You T, Gao X(高翔)*, Wang L*, Phytotoxicity and bioaccumulation of zinc oxide nanoparticles in rice (Oryza sativa L.). Plant Physiol Biochem. 2018 Sep; 130:604-612. (4)Shi H, Dong S, Zhang X, Chen X, Gao X(高翔)*, Wang L*. Phage vaccines displaying YGKDVKDLFDYAQE epitope induce protection against systemic candidiasis in mouse model. Vaccine. 2018 Sep 11;36(38):5717-5724. (5)Gao F, Liu B, Li M, Gao X, Fang Q, Liu C, Ding H, Wang L*, Gao X(高翔)*, Identification and Characterization of Terpene Synthase Genes Accounting for the Volatile Terpene Emissions in Flowers of Freesia hybrida, J Exp Bot. 2018 Volume 69, Issue 18, Pages 4249–4265 (6)Zhigang Ju, Wei Sun, Xiangyu Meng, Lingjie Liang, Yueqing Li, Tongtong Zhou, Huan Shen, Xiang Gao(高翔)*, Li Wang*, Isolation and functional characterization of two 5-Oglucosyltransferases related to anthocyanin biosynthesis from Freesia hybrida, Plant Cell, Tissue and Organ Culture, (2018) 135: 99. (7)Yicun Wang, Hongxi Shi, Shuai Dong, Yan Li, Meng Wang, Yanyan Huai, Xintong Zhang, Xi Chen, Chuanbin Mao, Xiang Gao(高翔)* and Li Wang*, Nontoxic engineered virus nanofiber as an efficient agent for prevention and detection of fungal infection, Nano Research, 11: 2248, 2018 (8)Dong S, Shi H, Zhang X, Chen X, Cao D, Mao C, Gao X*(高翔), Wang L*, Difunctional bacteriophage conjugated with photosensitizers for Candida albicans-targeting photodynamic inactivation, International Journal of Nanomedicine, 13: 2199—2216, 2018 (9)Tingting You, Dandan Liu, Jing Chen, Zhongzhou Yang, Runzhi Dou, Xiang Gao(高翔)*, Li Wang* (2018) Effects of metal oxide nanoparticles on soil enzyme activities and bacterial communities in two different soil types. J SOIL SEDIMENT, 18: 211. (10)Wei Sun, Xiangyu Meng, Lingjie Liang, Yueqing Li, Tongtong Zhou, Xinquan Cai, Li Wang, Xiang Gao(高翔)*(2017) Overexpression of a Freesia hybrida flavonoid 3-O-glycosyltransferase gene, Fh3GT1, enhances transcription of key anthocyanin genes and accumulation of anthocyanin and flavonol in transgenic petunia (Petunia hybrida). In Vitro Cell. Dev.Biol.—Plant, 53: 478. (11)Li Y, Liu X, Cai X, Shan X, Gao R, Yang S, Han T, Wang S, Wang L* and Gao X(高翔)* (2017) Dihydroflavonol 4-Reductase Genes from Freesia hybrida Play Important and Partially Overlapping Roles in the Biosynthesis of Flavonoids. Front. Plant Sci. 8:428. (12)Li S, Xia Q, Wang F*, Yu X, Ma J, Kou H, Lin X, Gao X(高翔)* and Liu B (2017) Laser Irradiation-Induced DNA Methylation Changes Are Heritable and Accompanied with Transpositional Activation of mPing in Rice. Front. Plant Sci. 8:363 (13)Shuai Dong, Hongxi Shi, Donghui Cao, Yicun Wang, Xintong Zhang, Yan Li, Xiang Gao(高翔)*, Li Wang*, Novel nanoscale bacteriophage-based single-domain antibodies for the therapy of systemic infection caused by Candida albicans, Scientific Reports, (2016) | 6:32256 (14)Yueqing Li, Xiaotong Shan, Ruifang Gao, Song Yang, Shucai Wang, Xiang Gao(高翔)*, Li Wang*, Two IIIf Clade-bHLHs from Freesia hybrida Play Divergent Roles in Flavonoid Biosynthesis and Trichome Formation when Ectopically Expressed in Arabidopsis, Scientific Reports, (2016) 6:30514 (15)Jing Chen, Runzhi Dou, Zhongzhou Yang, Xiaoping Wang, Chuanbin Mao, Xiang Gao(高翔)*, Li Wang*, The Effect and Fate of Water-Soluble Carbon Nanodots in Maize (Zea mays L.), Nanotoxicology, 2016, 10(6):818-828. (16)Wei Sun, Lingjie Liang, Xiangyu Meng, Yueqing Li, Fengzhan Gao, Xingxue Liu, Shucai Wang, Xiang Gao(高翔)* and Li Wang*,Biochemical and Molecular Characterization of a Flavonoid 3-O-glycosyltransferase Responsible for Anthocyanins and Flavonols Biosynthesis in Freesia hybrida,Front. Plant Sci. (2016) 7:410. (17)Wei Sun, Xiangyu Meng, Lingjie Liang, Wangshu Jiang, Yafei Huang, Jing He, Haiyan Hu, Jonas Almqvist, Xiang Gao(高翔)*, Li Wang*, Molecular and Biochemical Analysis of Chalcone Synthase from Freesia hybrid in Flavonoid Biosynthetic Pathway, (2015),PLoS ONE 10(3): e0119054. (18)Wang Y, Su Q, Dong S, Shi H, Gao X(高翔)*, Wang L*, Hybrid phage displaying SLAQVKYTSASSI induces protection against Candida albicans challenge in BALB/c mice, Hum Vaccin Immunother. (2014) 10(4):1057-63. (19)Gao X(高翔), Cao D, Liu J, Wang X, Geng S, Liu B, Shi D*, Tissue-Specific and Cation/Anion-Specific DNA Methylation Variations Occurred in C. virgata in Response to Salinity Stress, PLoS ONE,(2013) 8(11):e78426 (20)Wang QM, Wang YZ, Sun LL, Gao FZ, Sun W, He J, Gao X(高翔)*, Wang L*, Direct and indirect organogenesis of Clivia miniata and assessment of DNA methylation changes in various regenerated plantlets, Plant Cell Rep, (2012) 31:1283–1296

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