宋振波 - 东北师范大学 - 生命科学学院

个人简介

现为东北师范大学药物基因和蛋白筛选国家工程实验室副教授，硕士生导师，一直从事肿瘤发生机制和抗肿瘤药物筛选的研究。在国际著名期刊 Oncogene，Cell Death Dis，cell signal等发表SCI论文18篇,主持了2个C类科研项目以及1个D类项目和1个E类项目，并获得科研奖励2项。主要承担生物技术专业技术实践课和蛋白质与酶工程课程。工作经历 2018年8月～2019年9月美国明尼苏达大学访问学者 2017年6月～至今东北师范大学副教授 2015年6月～2017年5月东北师范大学讲师 2013年5月～2015年5月东北师范大学化学学院博士后研究学习经历 2006年9月～2011年7月东北师范大学遗传与细胞研究所硕博连读 2002年9月～2006年7月河南师范大学生命科学学院理学学士

研究领域

主要科研方向 1.肿瘤发病机制研究 2.肿瘤代谢研究 2.抗肿瘤中药新药筛选 3.中药抗肿瘤机制研究

近期论文

查看导师新发文章（温馨提示：请注意重名现象，建议点开原文通过作者单位确认）

1. Ai HH, Liu B, Yang MT, Zuo QQ, Song ZB*, Bao YL*, Sun LG, Zhou L, Li YX. Expression and effects of TSP50 in mouse embryo and cardiac myocyte development. Biochem Biophys Res Commun. 2018 Jul 12;502(2):283-288. 2.Song ZB, Wu P, Ni JS, Liu T, Fan C, Bao YL, Wu Y, Sun LG, Yu CL, Huang YX, Li YX (2017) Testes-specific protease 50 promotes cell proliferation via inhibiting activin signaling. Oncogene. doi:10.1038/onc.2017.198 3.Song ZB, Ni JS, Bao YL*, et al. （2015.）Testes-specific protease 50 promotes cell invasion and metastasis by increasing NF-kappaB-dependent matrix metalloproteinase-9 expression [J]. Cell Death Dis,6e1703 4.Yimeng Wang, Luguo Sun, Zhenbo Song, Danfeng Wang, Yongli Bao*, and Yuxin Li**. Maspin Inhibits Macrophage Phagocytosis and Enhances Inflammatory Cytokine Production via Activation of NF-κB Signaling. Molecular Immunology. 2017, 82:94-103 5. Ai HH, Zhou ZL, Sun LG*, Yang MT, Li W, Yu CL, Song ZB, Huang YX, Wu Y, Liu L, Yang XG, Zhao YQ, Bao YL*, Li YX. 20(S)-25-methoxyl-dammarane-3β, 12β, 20-triol negatively regulates activation of STAT3 and ERK pathways and exhibits anti-cancer effects in HepG2 cells. Apoptosis. 2017 Nov;22(11):1404-1418. 6.Song ZB, Liu B, Bao YL*, et al. 2014.The catalytic triad of testes-specific protease 50 (TSP50) is essential for its function in cell proliferation [J]. cellular signalling, 26(10):2266-2275 7.Zhenbo Song, Yongli Bao*, Yu Zhang, Xuguang Mi, Ping Wu, Yin Wu, ChunLei Yu, Ying Sun, LiHua Zheng, YanXin Huang, Biao Liu and YuXin Li*.Testes-specific protease 50 (TSP50) promotes cell proliferation through the activation of the NF-kappa beta (NF-κB) signaling pathway. Biochem J. 2011 Jun 1;436(2):457-67. 8.Yaqin Hou, Yao Yao, Yongli Bao*, Zhenbo Song*, Cheng Yang, Xiuli Gao, Wenjing Zhang, Luguo Sun, Chunlei Yu, Yanxin Huang, Guannan Wang, Yuxin Li. Juglanthraquinone C induces intracellular ROS increase and apoptosis by activating the Akt/FoxO signal pathway in HepG2 cells. Oxid Med Cell Longev. 2016:4941623. 9.Yan Li, Yannan Wu, Xinlei Yao, Fang Hao, Chunlei Yu, Yongli Bao, Yin Wu, Zhenbo Song, Ying Sun, Lihua Zheng, Guannan Wang, Yanxin Huang, Luguo Sun*, Yuxin Li*. Ginkgolide A Ameliorates LPS-Induced Inflammatory Responses In Vitro and In Vivo. Int J Mol Sci. 2017 Apr 10;18(4). pii: E794. doi: 10.3390/ijms18040794 10.Yimeng Wang, Luguo Sun, Zhenbo Song, Danfeng Wang, Yongli Bao*, Yuxin Li*. Maspin inhibits macrophage phagocytosis and enhances inflammatory cytokine production via activation of NF-κB signaling. Mol Immunol. 2017;82:94-103. 11.Wenjing Zhang, Zhenbo Song, Yongli Bao *, Wenling Li, Xiaoguang Yang, Qi Wang, Chunlei Yu, Luguo Sun, Yanxin Huang, Yuxin Li *. Periplogenin induces necroptotic cell death through oxidative stress in HaCaT cells and ameliorates skin lesions in the TPA- and IMQ-induced psoriasis-like mouse models. Biochem Pharmacol. 2016; 105:66-79. 12.Danfeng Wang, Yuqing Zhao, Yimeng Wang, Yan Rong, Hongshuang Qin, Yongli Bao*, Zhenbo Song, Chunlei Yu, Luguo Sun, Yuxin Li*. 25-methoxyl- dammarane-3, 12β, 20-triol and artemisinin synergistically inhibit MDA-MB-231 cell proliferation partially through down-regulation of testes-specific protease 50 expression. Tumor Biology, 2016, 37(9):11805-11813. 13.Hongshuang Qin, Peipei Yu, Ying Sun, Danfeng Wang, Xiaofen Deng, Yongli Bao*, Jun Song*, Luguo Sun, Zhenbo Song, Yuxin Li. Paclitaxel inhibits selenoprotein S expression and attenuates endoplasmic reticulum stress. MOL MED REP. 2016,13(5): 5118-5124. 14.Xiuli Gao, Hua Lin, Wei Zhao, Yaqin Hou, Yongli Bao*, Zhenbo Song, Luguo Sun, Shengyi Tian, Biao Liu*, Yuxin Li. JA, a new type of polyunsaturated fatty acid isolated from Juglans mandshurica Maxim, limits the survival and induces apoptosis of heptocarcinoma cells. Apoptosis. 2016,21(3):340-50. 15.Xuguang Mi, Zhenbo Song, Luguo Sun, Yongli Bao *, Chunlei Yu, Yin Wu, Yuxin Li. Cardamonin inhibited cell viability and tumorigenesis partially through blockade of testes-specific protease 50-mediated nuclear factor-kappaB signaling pathway activation. Int J Biochem Cell Biol. 2016 ,73: 63–71. 16.Cheng Yang, Dongmei Zhang, Zhenbo Song, Yaqin Hou, Yongli Bao*, Luguo Sun*, Chunlei Yu, Yuxin Li. Protumoral TSP50 regulates macrophage activities and polarization via production of TNF-α and IL-1β, and activation of the NF-κB signaling pathway. PLoS ONE. 2015, 10(12):e0145095. 17.Hongyan Wang, Yanxin Huang*, Lihua Zheng, Yongli Bao, Luguo Sun, Yin Wu, Chunlei Yu, Zhenbo Song, Ying Sun, Guannan Wang, Zhiqiang Ma*, Yuxin Li*. Modelling Coupled Oscillations in the Notch, Wnt, and FGF Signaling Pathways during Somitogenesis: A Comprehensive Mathematical Model．Computational Intellegence and Neruoscience, 2015, 2015:387409-1-16 18.Xuguang Mi, Zhenbo Song, Ping Wu, Yuwei Zhang, Luguo Sun, Yongli Bao*,Yu Zhang, Lihua Zheng, Ying Sun, Chunlei Yu, Yin Wu*, Guannan Wang, Yuxin Li. Alantolactone induces cell apoptosis partially through down-regulation of testes-specific protease 50 expression. Toxicology Letters, 2014, 224:349-355 19.Yunfeng Qi, Yanxin Huang*, Hongyan Wang, Yu Zhang, Yongli Bao, Luguo Sun, Yin Wu, Chunlei Yu, zhenbo song, Lihua Zheng, Ying Sun, Guannan Wang, Yuxin Li*. Elucidating the crosstalk mechanism between IFN-gamma and IL-6 via mathematical modelling. BMC Bioinformatics. 2013,14(1):41. 20.Cong Fan, Yanxin Huang*, Yongli Bao*, Luguo Sun, Yin Wu, Chunei Yu, Yu Zhang, Zhenbo Song, Lihua Zheng, Ying Sun, Gjuannan Wang, Yuxin Li*. Virtual Screening of Specific Insulin-Like Growth Factor 1 Receptor (IGF1R) Inhibitors from the National Cancer Institute (NCI) Molecular Database. Int J Mol Sci. 2012 Dec 14;13(12):17185-209.