黄艳新 - 东北师范大学 - 生命科学学院

个人简介

东北师范大学生命科学学院教授、博士生导师。1989年本科毕业于北京理工大学应用数学专业，计算机应用技术专业硕士、博士，细胞生物学专业博士后。主要学习简历 1985.9-1989.7 北京理工大学应用数学系应用数学专业本科生 1996.9-1999.3 长春理工大学计算机学院计算机应用专业硕士研究生 2001.9-2004.12 吉林大学计算机科学与技术学院计算机应用技术专业博士研究生 2006.12-2008.12 东北师范大学遗传与细胞研究所博士后主要工作简历 1989.7-1996.8 长春第一汽车制造厂助理工程师 1993.3-1994.5 日本共和电脑株式会社、日本富士通株式会社工作、研修 1999.3-2006.9 吉林大学计算机科学与技术学院讲师 2006.9-2009.4 吉林大学计算机科学与技术学院副教授 2009.4-2013.12 东北师范大学生命科学学院药物基因和蛋白筛选国家工程实验室副教授、博士生导师 2013.12至今东北师范大学生命科学学院药物基因和蛋白筛选国家工程实验室教授、博士生导师

研究领域

目前主要从事生物信息学和系统生物学的理论和应用研究，主要研究内容包括抗肿瘤和抗糖尿病药物分子计算机辅助筛选和实验验证，以及基于组学技术和计算系统生物学分析的药物分子作用机制研究。

近期论文

查看导师新发文章（温馨提示：请注意重名现象，建议点开原文通过作者单位确认）

[1]Fan C, Huang Y*. Identification of novel potential scaffold for class I HDACs inhibition: An in-silico protocol based on virtual screening, molecular dynamics, mathematical analysis and machine learning. Biochem Biophys Res Commun. 2017 Sep 23; 491(3): 800-806. [2]Huang YX*, Zhao J, Song QH, Zheng LH, Fan C, Liu TT, Bao YL, Sun LG, Zhang LB*, Li YX*. Virtual screening and experimental validation of novel histone deacetylase inhibitors. BMC Pharmacol Toxicol. 2016 Jul 21; 17(1): 32. [3]Wang HY, Huang YX*, Zheng LH, Bao YL, Sun LG, Wu Y, Yu CL, Song ZB, Sun Y, Wang GN, Ma ZQ, Li YX*. Modelling coupled oscillations in the Notch, Wnt, and FGF signaling pathways during somitogenesis: acomprehensive mathematical model. Comput Intell Neurosci. 2015;2015:387409. [4]Qi YF, Huang YX*, Dong Y, Zheng LH, Bao YL, Sun LG, Wu Y, Yu CL, Jiang HY, Li YX*. Systematic analysis of time-series gene expression data on tumor cell-selective apoptotic responses to HDACinhibitors. Comput Math Methods Med. 2014;2014:867289. [5]Wang HY, Huang YX*, Qi YF, Zhang Y, Bao YL, Sun LG, Zheng LH, Zhang YW, Ma ZQ*, Li YX*. Mathematical models for the Notch and Wnt signaling pathways and the crosstalk between them during somitogenesis. Theor Biol Med Model. 2013; 10(1): 27. [6]YF Qi, YX Huang*, HY Wang, Y Zhang, YL Bao, LG Sun, Y Wu, CL Yu, ZB Song, LH Zheng, Y Sun, GN Wang, YX Li*. Elucidating the crosstalk mechanism between IFN-gamma and IL-6 via mathematical modelling. BMC Bioinformatics. 2013, 14(1): 41. [7]J Huang*, Ratmir Derda, YX Huang. Phage Display Informatics. Comput Math Method M. vol 2013, pp: 698395. [8]C Fan, YX Huang*, YL Bao*, LG Sun, Y Wu, CL Yu, Y Zhang, ZB Song, LH Zheng, Y Sun, GN Wang, YX Li*. Virtual Screening of Specific Insulin-Like Growth Factor 1 Receptor (IGF1R) Inhibitors from the National Cancer Institute (NCI) Molecular Database. INT J MOL SCI. 2012, 13(12), 17185-17209. [9]YX Sun, YX Huang*, FL Li, HY Wang, C Fan, YL Bao, LG Sun, ZQ Ma, J Kong*, YX Li*. IVSPlat 1.0: an integrated virtual screening platform with a molecular graphical interface. CHEM CENT J. 2012, 6:2. [10]WH Chen, WW Guo, YX Huang*, ZQ Ma*. PepMapper: A Collaborative Web Tool for Mapping Epitopes from Affinity-Selected Peptides. PLoS ONE 2012, 7(5): e37869. [11]XW Zhao, JK Li, YX Huang*, ZQ Ma*, MH Yin*. Prediction of Bioluminescent Proteins Using Auto Covariance Transformation of Evolutional Profiles. INT J MOL SCI. 2012, 13(3), 3650-3660. [12]ZL Cao, JZ Meng, XX Li, RP Wu, YX Huang, YX He*. The Epitope and Neutralization Mechanism of AVFluIgG01, a Broad-Reactive Human Monoclonal Antibody against H5N1 Influenza Virus. PLoS ONE 2012, 7(5): e38126. [13]M Zheng, JN Wu, YX Huang, GX Liu, Y Zhou*, CG Zhou. Inferring Gene Regulatory Networks by Singular Value Decomposition and Gravitation Field Algorithm. PLoS ONE 2012, 7(12): e51141. [14]M Zheng, YX Huang, W Shen, Y Zhong, JN Wu, GX Liu*, Y Zhou*. A novel scale-free network construction method and its application in gene expression profiles simulation. PROG BIOCHEM BIOPHYS. 2012, 39(6): 581-590. [15]PP Sun, WH Chen, YX Huang*, HY Wang, ZQ Ma*, YH Lv*. Epitope prediction based on random peptide library screening: Benchmark datasets and prediction tools evaluation. Molecules 2011; 16(6): 4971-4993. [16]WH Chen, PP Sun, Y Lu, WW Guo, YX Huang*, ZQ Ma*. MimoPro. a more efficient Web-based tool for epitope prediction using phage display libraries. BMC Bioinformatics 2011; 12: 199. [17]YX Huang, YL Bao*, SY Guo, Y Wang, CG Zhou, YX Li*. Pep-3D-Search: a method for B-cell epitope prediction based on mimotope analysis. BMC Bioinformatics, 2008, 9:538. [18]黄艳新, 鲍永利*, 李玉新*. 抗原表位预测的免疫信息学方法研究进展. 中国免疫学杂志, 2008, Vol 24, No 9, pp 857-861.