个人简介
一、主要学习简历(含国内外访学)
1986.9-1991.7 白求恩医科大学医学系 大学本科 获学士学位
1991.9-1994.7 白求恩医科大学免疫教研室 硕士研究生 获硕士学位
1998.10-2001.12吉林大学免疫教研室 博士研究生 获博士学位
2000.3--2005.3 日本德岛大学分子酶研究中心 博士研究生 获博士学位
2002.12-2006.7 东北师范大学遗传与细胞研究所 博士后
二、主要工作简历
1994.7-1996.8 白求恩医科大学免疫教研室 助教
1996.8-2000.3 白求恩医科大学免疫教研室 讲师
2001.12-2002.11 东北师范大学遗传与细胞研究所 讲师
2002.12-2007.9 东北师范大学遗传与细胞研究所 副教授、硕士生导师
2007.10-2008.11 东北师范大学药物基因和蛋白筛选国家工程实验室 副教授、博士生导师
2008.12-至今 东北师范大学药物基因和蛋白筛选国家工程实验室 教授、博士生导师
近期论文
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1. Ai HH, Liu B, Yang MT, Zuo QQ, Song ZB*, Bao YL*, Sun LG, Zhou L, Li YX. Expression and effects of TSP50 in mouse embryo and cardiac myocyte development. Biochem Biophys Res Commun. 2018 Jul 12;502(2):283-288.
2. Yang M, Zhao H, Ai H, Zhu H, Wang S, Bao Y*, Li Y. Alantolactone suppresses APOC3 expression and alters lipid homeostasis in L02 liver cells. Eur J Pharmacol. 2018 Jun 5;828:60-66.
1.Z-B Song, P Wu, J-S Ni, T Liu, C Fan, Y-L Bao*, Y Wu, L-G Sun, C-L Yu,Y-X Huang and Y-X Li**. Testes-specific protease 50 promotes cell proliferation via inhibiting activin signaling. Oncogene, (26 June 2017), doi:10.1038/onc.2017.198. (IF:7.519)
2.Yimeng Wang, Luguo Sun, Zhenbo Song, Danfeng Wang, Yongli Bao*, and Yuxin Li**. Maspin Inhibits Macrophage Phagocytosis and Enhances Inflammatory Cytokine Production via Activation of NF-κB Signaling. Molecular Immunology. 2017, 82:94-103.(IF:3.236)
3. Ai HH, Zhou ZL, Sun LG*, Yang MT, Li W, Yu CL, Song ZB, Huang YX, Wu Y, Liu L, Yang XG, Zhao YQ, Bao YL*, Li YX. 20(S)-25-methoxyl-dammarane-3β, 12β, 20-triol negatively regulates activation of STAT3 and ERK pathways and exhibits anti-cancer effects in HepG2 cells. Apoptosis. 2017 Nov;22(11):1404-1418.
4.Cao Y, Yi J, Yang X, Liu L, Yu C, Huang Y, Sun L*, Bao Y*, Li Y*. Efficient Cancer Regression by a Thermosensitive Liposome for Photoacoustic Imaging-Guided Photothermal/Chemo Combinatorial Therapy. Biomacromolecules. 2017 Aug 14;18(8):2306-2314.
5.Cao Y, Wu Y, Wang G, Yi J, Yu C, Huang Y, Sun L*, Bao Y*, Li Y*. Near-infrared conjugated polymers for photoacoustic imaging-guided photothermal/chemo combination therapy. J MATER CHEM, 2017, 5:5479-5487.
1.Hou YQ, Yao Y, Bao YL*, Song ZB*, Yang C, Gao XL, Zhang WJ, Sun LG, Yu CL, Huang YX, Wang GN, Li YX. Juglanthraquinone C induces intracellular ROS increase and apoptosis by activating the Akt/FoxO signal pathway in HepG2 cells. Oxid Med Cell Longev. 2016;2016:4941623.
2.Zhang DM, Bao YL*, Yu CL, Wang YM, Song ZB. Cripto-1 modulates macrophage cytokine secretion and phagocytic activity via NF-κB signaling. Immunol Res. February 2016, Volume 64, Issue 1, pp 104-114.
3.Gao XL, Lin H, Zhao W, Hou YQ, Bao YL*, Song ZB, Sun LG, Tian SY, Liu B*, Li YX. JA, a new type of polyunsaturated fatty acid isolated from Juglans mandshurica Maxim, limits the survival and induces apoptosis of heptocarcinoma cells. Apoptosis. 2016 Mar; 21(3):340-50. doi: 10.1007/s10495-015-1202-5.
4.Mi XG, Song ZB, Sun LG, Bao YL*, Yu CL, Wu Y, Li YX. Cardamonin inhibited cell viability and tumorigenesis partially through blockade of testes-specific protease 50-mediated nuclear factor-kappaB signaling pathway activation. Int J Biochem Cell Biol. 2016 Volume 73, April 2016, Pages 63–71.
5.Zhang WJ, Song ZB, Bao YL*, Li WL, Yang XG, Wang Q, Yu CL, Sun LG, Huang YX and Li YX*. Periplogenin induces necroptotic cell death through oxidative stress in HaCaT cells and ameliorates skin lesions in the TPA- and IMQ-induced psoriasis-like mouse models. Biochem Pharmacol. April 1. 2016, 105:66-79.
6.Qin HS, Yu PP, Sun Y, Wang DF, Deng XF, Bao YL*, Song J*, Sun LG, Song ZB and Li YX. Paclitaxel inhibits selenoprotein S expression and attenuates endoplasmic reticulum stress. MOL MED REP. 2016,13(5):5118-5124.
7.Danfeng Wang, Yuqing Zhao, Yimeng Wang, Yan Rong, Hongshuang Qin,Yongli Bao*, Zhenbo Song, Chunlei Yu, Luguo Sun, and Yuxin Li*. 25-methoxyl-dammarane-3, 12β, 20-triol and artemisinin synergistically inhibit MDA-MB-231 cell proliferation partially through down-regulation of testes-specific protease 50 expression. Tumor Biology. 2016, 37:11805–11813."