个人简介
学习经历（含国外研修经历）
1989.9–1994.6 白求恩医科大学 临床医学系 本科生
1994.9–1997.6 白求恩医科大学 生物化学系 硕士研究生
1997.9–2000.6 白求恩医科大学 免疫学系 博士研究生
2001.7–2004.7 香港科技大学 生物化学系 博士后
2005.5–2006.4 美国Cleveland Clinic Lerner研究所 细胞生物学系 博士后
工作简历
1997.7–1999.7 白求恩医科大学基础医学院分子生物学教研室 助教
1999.7–2004.8 白求恩医科大学基础医学院分子生物学教研室 讲师
（吉林大学白求恩医学院分子生物学教研室）
2004.9–2009.8 吉林大学白求恩医学院分子生物学教研室 副教授
2009.9–2011.3 吉林大学白求恩医学部 教授
2011.4–今 东北师范大学药物基因和蛋白筛选国家工程实验室 教授
近期论文
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1. Yucui Liu, Yanjie Xu, Qiuhang Song, Fei Wang, Luguo Sun**, Lei Liu, Xiaoguang Yang, Jingwen Yi, Yongli Bao, Haifeng Ma, Honglan Huang***, Chunlei Yu, Yanxin Huang, Yin Wu*, Yuxin Li. Anti-biofilm Activities from Bergenia crassifolia Leaves against Streptococcus mutansFront Microbiol. 2017 Sep 13;8:1738. doi: 10.3389/fmicb.2017. 01738. eCollection 2017.
2. Hui-Han Ai, Zi-Long Zhou, Lu-Guo Sun*, Mei-Ting Yang, Wei Li, Chun-Lei Yu, Zhen-Bo Song, Yan-Xin Huang, Yin Wu, Lei Liu, Xiao-Guang Yang, Yu-Qing Zhao***, Yong-Li Bao**, Yu-Xin Li. 20(S)-25-methoxyl-dammarane- 3β, 12β, 20-triol negatively regulates activation of STAT3 and ERK pathways and exhibits anti-cancer effects in HepG2 cells. Apoptosis. 2017 Sep 1. doi: 10.1007/s10495-017-1416-9. [Epub ahead of print] PubMed PMID: 28864870.
3. Yan Li, Yannan Wu, Xinlei Yao, Fang Hao, Chunlei Yu, Yongli Bao, Yin Wu, Zhenbo Song, Ying Sun, Lihua Zheng, Guannan Wang, Yanxin Huang, Luguo Sun*, Yuxin Li**. Ginkgolide A Ameliorates LPS-Induced Inflammatory Responses In Vitro and In Vivo. Int J Mol Sci. 2017 Apr 10;18(4). pii: E794. doi: 10.3390/ijms18040794
4. Yue Cao, Xiaoguang Yang, Yannan Wu, Jingwen Yi, Yin Wu, Chunlei Yu, Yanxin Huang, Yongli Bao***, Luguo Sun*, Yuxin Li**. Dual release of angiostatin and curcumin from biodegradable PLGA microspheres inhibit Lewis lung cancer in a mice model. RSC Adv. 2016(10): 111440-111446
5. Yue Cao, Yan Li, Yin Wu, Wenling Li, Chunlei Yu, Yanxin Huang, Luguo Sun*, Yongli Bao***, Yuxin Li**. Co-Delivery of angiostatin and curcumin by a biodegradable polymersome for antiangiogenic therapy. RSC Adv. 2106, 6: 105442-105448
6. Cheng Yang, Dongmei Zhang, Zhenbo Song, Yaqin Hou, Yongli Bao*, Luguo Sun**, Chunlei Yu, Yuxin Li. Protumoral TSP50 regulates macrophage activities and polarization via production of TNF-α and IL-1β, and activation of the NF-κB signaling pathway. PLoS ONE. 2015, 10(12):e0145095.
7. Luguo Sun, Liyan Sui, Xinlin Cong, Kejuan Ma, Xiaobo Ma, Yanxin Huang, Chong Fan, Xueqi Fu, Kewei Ma*. Low incidence of IL6ST(gp130) mutations in exon6 in lung cancer of a Chinese cohort. Cancer Genet. 2014 Jul-Aug;207(7-8):291-8. doi: 10.1016/j.cancer gen.2014.07.003. Epub 2014 Aug 1.
8. Luguo Sun, Xia Cao, Bin Liu, Honglan Huang, Xu Wang, Liyan Sui, Weimin Yin, Kewei Ma*. CaMKIV phosphorylates prohibitin 2 and regulates prohibitin 2-mediated repression of MEF2 transcription. Cell Signal. 2011 Oct; 23(10): 1686-90.
9. Fang Xiao, Haixia Wang, Xinrong Fu, Yanfeng Li, Kewei Ma, Luguo Sun, Xiang Gao, Zhenguo Wu*. Oncostatin M inhibits myoblast differentiation and regulates muscle regeneration. Cell Res. 2011 Feb;21(2):350-64.
10. Bohan Dong※, Luguo Sun※, Xiuli Wu, Peiyin Zhang, Li Wang, Hongfei Wei, Lei Zhou, Xiaoping Hu, Yongli Yu, Shucheng Hua*, Liying Wang*. Vaccination with TCL plus MHSP65 induces anti-lung cancer immunity in mice. Cancer Immunol Immunother. 2010 Jun; 59(6):899-908.（共第一作者）
11. Yanping Yang, Ying Xu, Wei Li, Guanjun Wang, Yanqiu Song, Guozi Yang, Xue Han, Zhonghua Du, Luguo Sun*, Kewei Ma*. STAT3 induces muscle stem cell differentiation by interaction with myoD. Cytokine. 2009 Apr;46(1):137-41.
12. Sun L, Ma K , Wang H, Xiao F, Gao Y, Zhang W, Wang K, Gao X, IP N and Wu Z. JAK1-STAT1-STAT3, a key pathway promoting proliferation and preventing premature differentiation of myoblasts. J. Cell Biol. 2007;179(1): 129-138
13. Sun L, Liu L, Yang XJ and Wu Z. Akt binds Prohibitin 2 and relieves its repression on MyoD and muscle differentiation. J. Cell. Sci. 2004 Jun;117:3021-9. 117: 3021-3029
14. Wan J, Sun L, Mendoza WJ, Chui YL, Huang DP, Chen XJ, Suzuki N, Suzuki S, Yeh WC, Akira S, Matsumoto K, Liu XG, and Wu Z. Elucidation of the JNK pathway mediated by Epstein-Barr virus encoded latent membrane protein 1. Mol. Cell Biol. 2004 Jan;24(1): 192-199.
15.Chan JK, Sun L, Yang XJ, Zhu G, and Wu Z. Functional characterization of an amino terminal region of HDAC4 that possesses MEF2 binding and transcriptional repressive activity. J. Biol. Chem. 2003 Jun; 278: 23515 – 23521.
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