李瑞宾 - 苏州大学 - 医学部放射医学与防护学院

个人简介

李瑞宾，现任苏州大学医学部教授，主要从事纳米生物学的研究。已发表学术论文65篇，SCI他引3300多次，H指数34。已发表通讯作者论文18篇，包括J Am Chem Soc, Nat Commun, Angew Chem Int Ed, Environ Health Perspect, Nano Today，ACS Nano，Small，Particle & Fiber Toxicology等。2016年获得国家“海外高层次人才计划”青年项目，2020年入选Elsevier “中国高被引学者”，获得江苏省“双创团队”、 “杰出青年科学基金”资助。担任Elsevier旗下NanoImpact期刊（IF：5.3）副主编。主持国家级科技项目4项，包括科技部国际合作重点研发项目1项、基金委面上项目2项，省级项目6项。

研究领域

纳米药理毒理学放射纳米诊疗新技术耐药微生物防治新策略

近期论文

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Gao M., Liu X., Wang Z., Wang H., Assetc T., Wu D., Jiang J., Xie Q., Xu S., Cai X., Li J., Wang W., Zheng Z., Gao X., Tarasenkoe N., Rotonnellif, B., Galletg, J., Jaouenc F., Li, R.* Engineering catalytic dephosphorylation reaction for endotoxin inactivation, Nano Today 2022, 101456. Zheng, H.; Gu, Z.; Pan, Y.; Chen, J.; Xie, Q.; Xu, S.; Gao, M.; Cai, X.; Liu, S.; Wang, W.; Liu, X.; Yang, Z.*; Zhou, R.; Li, R.* Biotransformation of rare earth oxide nanoparticles eliciting microbiota imbalance, Part. Fibre Toxicol. 2021, 18:1. Zheng, H.; Jiang, J.; Xu, S.; Liu, W.; Xie, Q.; Cai, X.; Zhang, J.; Liu, S.; Li, R.*, Nanoparticle-induced ferroptosis: detection methods, mechanisms and applications,Nanoscale2020, 59, 22431-22439. Ma, R.; Cai, X.; Zhou, Y.; Liu, X.; Wu, D.; Zheng, H.; Pan, Y.; Jiang, J.; Xu, S.; Xie, Jie Jiang, Q.; Wang, W.; Tarasenko, N.; Wang, F.*; Li, R.* Emerging investigator series: long-term exposure of amorphous silica nanoparticles disrupts the lysosomal and cholesterol homeostasis in macrophages, Evironment. Sci: Nano 2021, DOI: 10.1039/d1en00696g. Wang, W.; Kong, Y.; Jiang, J.; Xie, Q; Huang, Y.; Li, G.; Wu, D.; Zheng, H.; Gao, M.; Xu S.; Pan, Y.; Li, W.; Ma, R.; Li, X.; Zuilhof, Z.; Cai, C.;Li, R.*, Engineering the Protein Corona Structure on Gold Nanoclusters Enables Red‐Shifted Emissions in the Second Near‐infrared Window for Gastrointestinal Imaging,Angew. Chem. Int. Ed.2020, 59, 22431-22439. Wu, D.; Li, J.; Xu, S.; Xie, Q.; Pan, Y.; Liu, X.; Ma, R.; Zheng, H.; Gao, M.; Wang, W.; Li, J.; Cai, X.; Jaouen, F.*; Li, R.*, Engineering Fe-N Doped Graphene to Mimic Biological Functions of NADPH Oxidase in Cells, J. Am. Chem. Soc., 2020, 142, 19602-19610. Gao, M.; Wang, Z.; Zheng, H.; Wang, L.; Xu, X.; Liu, X.; Li, W.; Pan, Y.; Wang, W.; Cai, X.; Wu, R.; Gao, X.*; Li, R.*, Two-Dimensional Tin Selenide (SnSe) Nanosheets Capable of Mimicking Key Dehydrogenases in Cellular Metabolism, Angew. Chem.Int. Ed. 2020, 132, 3618-3623. Xu, S.; Zheng, H.; Ma, R.; Wu, D.; Pan, Y.; Yin, C.; Gao, M.; Wang, W.; Li, W.; Liu, S.; Chai, Z.; Li, R.*,Vacancies on 2D transition metal dichalcogenides elicit ferroptotic cell death,Nat. Commun. 2020, 11, 3484. Huang, Y.; Li, X*.; Xu, S.; Zheng, H.; Zhang, L.; Chen, J.; Hong, H.; Kusko, R.; Li. R.*, Quantitative Structure–Activity Relationship Models for Predicting Inflammatory Potential of Metal Oxide Nanoparticles, Environ. Health Perspect.2020, 128, 067010. Cai, X.; Liu, X.; Jiang, J.; Gao, M.; Wang, W.; Zheng, H.; Xu, S.; Li, R.*, Molecular Mechanisms, Characterization methods and Utilities of Nanoparticle Biotransformation in Nanosafety Assessments, Small 2020, 1907663. Zheng, H.; Ji, Z.; Roy, K.; Gao, M.; Pan, X.; Cai, X.; Wang, L.; Li, W.; Chang, C.; Kaweeteerawat, C.; Chen, C.; Xia, T.; Zhao, Y.; Li, R*, ACS Nano 2019, 11488. Ma, R.; Zheng, H.; Liu, Q.; Wu, D.; Li, W.; Xu, S.; Cai, X.; Li, R*. Exploring the interactions between engineered nanomaterials and immune cells at 3D nano-bio interfaces to discover potent nano-adjuvants, Nanomedicine: NBM 2019, 21, 102037. Cai, X.; Dong, J.; Liu, J.; Zheng, H.; Kaweeteerawat, C.; Wang F., Ji Z.*; Li, R.*, Multi-hierarchical profiling the structure-activity relationships of engineered nanomaterials at nano-bio interfaces, Nat. Commun. 2018, 9, 4416. Li, R.; Guiney, L.; Chang, C.; Mansukhani, N.; Ji, Z.; Wang, X.; Liao, Y.; Jiang, W.; Sun, B.; Hersam, M. Nel, A.*; Xia, T.*, Surface oxidation of graphene oxide determines membrane damage, lipid peroxidation, and cytotoxicity in macrophages in a pulmonary toxicity model, ACS Nano, 2018, 1390. Zheng, H.; Ma, R.; Gao, M.; Tian, X.; Li, Y.; Zeng, L.*; Li, R.*, Antibacterial applications of graphene oxides: structure-activity relationships, molecular initiating events and biosafety, Sci. Bull. 2018, 133. Cai, X.; Lee, A.; Ji, Z.; Huang, C.; Chang, C. H.; Wang, X.; Liao, Y.-P.; Xia, T.*; Li, R.*, Reduction of pulmonary toxicity of metal oxide nanoparticles by phosphonate-based surface passivation. Part. Fibre Toxicol.2017,14：13.