薛松 - 北京化工大学 - 生命科学与技术学院

个人简介

教育背景： 2013.8-2018.5 The Scripps Research Institute 博士（生物与生物医学科学专业） 2008.8-2012.7 清华大学化学系，学士（化学生物学专业）工作经历： 2012.7-2013.6 清华大学研究助理 2018.7-至今北京化工大学生命科学与技术学院，副教授

研究领域

蛋白与蛋白/多肽/小分子相互作用蛋白的定向改造神经退行性疾病机理与抑制剂研究免疫检查点蛋白的多肽与小分子抑制剂开发

近期论文

查看导师新发文章（温馨提示：请注意重名现象，建议点开原文通过作者单位确认）

1. Xue, S., Javor, S., Hixon, M. S., & Janda, K. D. * (2014). Probing BoNT/A protease exosites: implications for inhibitor design and light chain longevity. Biochemistry, 53(43), 6820-6824. 2. Xue, S., Schlosburg, J. E., & Janda, K. D. * (2015). A new strategy for smoking cessation: Characterization of a bacterial enzyme for the degradation of nicotine. Journal of the American Chemical Society, 137(32), 10136-10139. 3. Seki, H., Xue, S., Hixon, M. S., Pellett, S., Remes, M., Johnson, E. A., & Janda, K. D. * (2015). Toward the discovery of dual inhibitors for botulinum neurotoxin A: concomitant targeting of endocytosis and light chain protease activity. Chemical Communications, 51(28), 6226-6229. 4. Seki, H.1, Xue, S.1, Pellett, S., Šilhár, P., Johnson, E. A., & Janda, K. D. * (2016). Cellular Protection of SNAP-25 against Botulinum Neurotoxin/A: Inhibition of Thioredoxin Reductase through a Suicide Substrate Mechanism. Journal of the American Chemical Society, 138(17), 5568-5575. 5. Bremer, P. T., Xue, S., & Janda, K. D. * (2016). Picolinic acids as β-exosite inhibitors of botulinum neurotoxin A light chain. Chemical Communications, 52(84), 12521-12524. 6. Xue, S., Seki, H., Remes, M., Šilhár, P. & Janda, K. D. * (2017). Examination of α-exosite inhibitors against Botulinum neurotoxin A protease through structure-activity relationship studies of chicoric acid. Bioorganic & Medicinal Chemistry Letters, 27(22), 4956-4959. 7. Xue, S.1, Kallupi M.1, Zhou B., Smith, L. C., Miranda, P. O., George, O., & Janda, K. D. * (2018). An Enzymatic Advance in Nicotine Cessation Therapy. Chemical Communications, 54 (14), 1686-1689 (front cover). 8. Tararina, M.1, Xue, S.1, Smith, L. C., Muellers, S., Miranda, P. O., Janda, K. D., & Allen, K. * (2018). Crystallography Coupled with Kinetic Analysis Provide Mechanistic Underpinnings of a Nicotine-Degrading Enzyme. Submitted to Biochemistry, 57 (26): 3741–3751. 9. Kallupi M.1*, Xue, S.1, Zhou B., George, O.*, & Janda, K. D. (2019) Enzymatic approach to reverse nicotine dependence, decrease compulsive-like intake, and prevent relapse. Science Advances, 4 (10), eaat4751. 10. Chen, C., Ding, X., Akram, N., Xue, S. *, & Luo, S. Z. * (2019). Fused in Sarcoma: Properties, Self-Assembly and Correlation with Neurodegenerative Diseases. Molecules, 24(8), 1622.