陈必强 - 北京化工大学 - 生命科学与技术学院

个人简介

教育背景： 2001 学士，生物化工（北京化工大学） 2003 硕士，生物化工（北京化工大学） 2008 博士，生物化工（北京化工大学） 2006/01-2006/07 赴丹麦技术大学进行博士联合培养 2008.8-2010.6 博士后（清华大学化工系）工作经历： 2010.8-2014.12，北京化工大学生命学院，副教授，硕士生导师 2015.1-2018.1，北京化工大学生命学院，见习教授，硕士生导师 2018.1-至今，北京化工大学生命学院，教授，博士生导师

研究领域

长期从事生物催化剂工程的研究。作为项目负责人主持国家自然科学基金2项、国家973计划子课题2项、863计划子课题1项，企业横向课题2项。近年发表SCI论文30多篇，申请专利11项（已授权6项，包括国际专利1项）。具体研究方向：新酶的筛选与酶的蛋白质工程改造酶的固定化微环境调控多酶催化体系构建新型酶反应器设计与酶反应过程在线监测、控制与系统集成生物催化新产品、新工艺开发

近期论文

查看导师新发文章（温馨提示：请注意重名现象，建议点开原文通过作者单位确认）

1）Cui C, Chen H, Chen B*, et al. Genipin Cross-Linked Glucose Oxidase and Catalase Multi-enzyme for Gluconic Acid Synthesis (2016). Applied Biochemistry and Biotechnology, 1-10. 2）Cui, C., Nan, G., Chen, X., Chen, B*., & Tan, T*. (2016). Immobilization of yarrowia lipolytica, lipase ylip 2 for the bioicatalytic synthesis of phytosterol ester in a water activity controlled reactor. Colloids & Surfaces B Biointerfaces, 146, 490-497. 3）Cui, C., Zhen, Y., Qu, J., Chen, B*., & Tan, T*. (2016). Synthesis of biosafe isosorbide dicaprylate ester plasticizer by lipase in a solvent-free system and its sub-chronic toxicity in mice. Rsc Advances, 6(15), 11959-11966. 4）Tao, Y., Dong, R., Pavlidis, I. V., Chen, B*., & Tan, T. (2015). Using imidazolium-based ionic liquids as dual solvent-catalysts for sustainable synthesis of vitamin esters: inspiration from bio- and organo-catalysis. Green Chemistry, 18(5), 1240-1248. 5）Tao, Y., Chen, G., Pavlidis, I. V., Jiang, Y., Qie, L., & Cui, C., Liu L., Chen, B*, & Tan, T.* (2015). Water-dependent kinetics guide complex lipase-mediated synthesis of biolubricants in a water activity control reactor. Catalysis Science & Technology, 5(12), 5120-5128. 6）Cui, C., Tao, Y., Ge, C., Zhen, Y., Chen, B*., & Tan, T*. (2015). Synergistic effects of amine and protein modified epoxy-support on immobilized lipase activity. Colloids & Surfaces B Biointerfaces, 133(1), 51-57. 7）Rong, X., Cui, C., Chen, B*., & Tan, T. (2015). Immobilizing yarrowia lipolytica, lipase lip2 via improvement of microspheres by gelatin modification. Applied Biochemistry & Biotechnology, 177(3), 1-9. 8）Cui, C., Xie, R., Tao, Y., Zeng, Q., Chen, B*, & Tan T*. (2015). Improving performance of yarrowia lipolytica, lipase lip2-catalyzed kinetic resolution of (R,S)-1-phenylethanol by solvent engineering. Biocatalysis & Biotransformation, 33(1), 38-43. 9）Tao, Y., Cui, C., Shen, H., Luo, L., Chen, B*., & Tan, T*. (2014). Enhancing trimethylolpropane esters synthesis through lipase immobilized on surface hydrophobic modified support and appropriate substrate feeding methods. Enzyme & Microbial Technology, 58-59(9), 60-67. 10）Chen, Biqiang，Zhang, Hong，Cheong, Ling-Zhi，Tan, Tianwei，Xu, Xuebing ，Enzymatic Production of ABA-Type Structured Lipids Containing Omega-3 and Medium-Chain Fatty Acids: Effects of Different Acyl Donors on the Acyl Migration Rate，Food and Bioprocess Technology，2012，5（2）：541-547