侯一平 - 兰州大学 - 甘肃省新药临床前研究重点实验室

个人简介

1978-1983 兰州医学院临床医学系,获学士学位。 1983-1989 兰州医学院人体解剖教研室，助教。 1985-1988 兰州医学院解剖教研室研究生,硕士研究生，获硕士学位。 1989-1991 兰州医学院解剖教研室，讲师。 1992-1993 法国里昂第一大学科学院，留学，导师:Dr. L. ASTIC。 1993-1995 法国里昂第一大学医学院，博士后，导师: Prof. M. Jouvet and Dr. JS. Lin。 1995-1998 兰州医学院副教授。 1999-2000 加拿大蒙特利尔McGill大学，访问学者。导师: Prof. B. E. Jones。 1999-2004 兰州医学院教授。 2005- 兰州大学基础医学院人体解剖与组织胚胎研究所，神经科学研究所，教授。

研究领域

睡眠-觉醒的机制和睡眠疾病。神经毒素-肉毒素毒素作用机理及临床应用。

近期论文

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Wang XW, Gu JY, Li Z, Song YF, Wu WS, Hou YP*. Gestational age and dose influence on placental transfer of 63Ni in rats. Placenta 2010; 31:305-311. SCI Li Z, Gu JY, Wang XW, Fan QH, Ge YX, Jiao ZX, Hou YP, Wu WS. Effects of cadminum on sbstorption, excretion, and distribution of nickel in rats. Biol Trace Elem Res 2010; 135(1-3):211-219. SCI Zhang X, Sun YN, Xie P, Yang XG, Hou YP* Effect of microinjecting GABAA-receptor antagonist into the tuberomammillary nucleus on the sleep-wakefulness cycle after lesion of the ventrolateral preoptic area in rats. Neural Regen Res 2009; 4(1):53-57 SCI Zhu CM, Yao XR, Zhang WS, Song YF, Hou YP*. Progressive paradoxical sleep deprivation impairs partial memory and influences motor behavior following learning tasks in rats. Neural Regen Res 2008; 3(6):598-603 SCI Wen WD, Yuan F, Wang JL, Hou YP*. Botulinum toxin therapy in the ovalbumin-sensitized rat. Neuroimmunomodulation 2007; 14(2):78-83. SCI Hou YP, Zhang YP, Song YF, Zhu CM, Wang YC, Xie GL. Botulinum toxin type A inhibits rat pyloric myoelectrical activity and substance P release in vivo. Can J Physiol Pharmacol 2007; 85(2): 209-214. SCI Manns ID, Lee MG, Hou YP, Jones BE. Alpha 2 adrenergic receptors on GABAergic, putative sleep-promoting basal forebrain neurons. Euro J Neurosci 2003; 18:723-727. SCI Hou YP, Manns ID, Jones BE. Immunostaining of choliergic pontomesencephallic neurons for α1 versus α2 adrenergic receptors suggests different sleep-wake state activities and roles. Neuroscience 2002; 114 (3):517-521. SCI Lin JS, Gervasoni D, Hou Y, Vanni-Mercier G, Rambert F, Frydam A, Jouvet M. Effects of amphetamine and modafinil on the sleep/wake cycle during experimental hypersomnia induced by sleep deprivation in the cat. J. Sleep Res. (2000) 9:89-96. SCI Hou YP，Lin JS. Effects of modafinil and amphetamine on sleep-wake cycle after sleep deprivation in cats. Acta. Pharmacologica. Sinica. 1999; 20(9):813-818. SCI Lin JS, Hou Y, Rambert FA, Jouvet M. A wakening profiles of modafinil in sleep-deprived cats and its induction of brain c-fos expression pattern distinct from that caused by amphetamine or methylphenidate. Sleep Research (1997), 26:23 SCI Lin JS, Hou Y, Jouvet M. Potential brain neuronal targets for amphetamine-, methylphenidate-, and modafinil-induced wakefulness, evidenced by c-fos immunocytochemistry in the cat. PNAS USA 1996; 93:14128-14133 SCI Lin JS, Hou Y, Sakai K, Jouvet M. Histaminergic Descending Inputs to the Mesopontine Tegmentum and their Role in the Control of Cortical Activation and Wakefulness in the cat, J. Neuroscience 1996; 16(4): 1523-1537. SCI Lin JS, Hou Y, Kitahama K, Jouvet M. Selective suppression of type B monoamine oxidase immunoreactivity in the raphe nuclei following MPTP administration in the cat, NeuroReport 1995; 6:321-324. SCI Hou Y, Giannetti N. Calcitoningene-related peptide immunoreactivity in the rat peripheral olfactory system during post-natal development, European Chemoreception Research Organization XI Congress, Chemi Sense 1994; 16:88. SCI