赵镭 - 华南理工大学 - 生物科学与工程学院

个人简介

教育经历 2006.09 – 2012.06 清华大学化学系博士 2008.08 – 2008.11 德国柏林洪堡大学化学系联合培养博士 2009.06 – 2009.09 德国柏林洪堡大学化学系联合培养博士 2002.09 – 2006.06 南京大学化学化工学院本科工作经历 2017.12 – 至今华南理工大学生物科学与工程学院副教授 2012.09 – 2017.04 德国马普分子生理学研究所马普学会化学基因组中心博士后研究员

研究领域

多肽与蛋白质化学。包括多肽的化学与生物合成、修饰多肽的合成、蛋白质的半合成、蛋白翻译后修饰、蛋白质标记、蛋白-蛋白相互作用的研究、疾病相关蛋白的功能研究等。

近期论文

查看导师新发文章（温馨提示：请注意重名现象，建议点开原文通过作者单位确认）

Lei Zhao, Christiane Ehrt, Oliver Koch, Yao-Wen Wu*.One-Pot N2C/C2C/N2N Ligation To Trap Weak Protein-Protein Interactions, Angew Chem Int Ed Engl. 2016 Jul 4;55(28):8129-33 (被选为封面文章，被X-Mol网站报道http://www.x-mol.com/news/3542) (IF: 11.709) Aimin Yang#, Lei Zhao#, Yao-Wen Wu*, Chemical Synthesis and Biological Function of Lipidated Proteins, Topics in Current Chemistry, 2015; 362: 137-82 (# 共同一作) (IF: 4.014) Yao-Wen Wu*, Lei Zhao, Elucidation of Protein Function by Chemical Modification, Concepts and Case Studies in Chemical Biology, 06/2014: 83-104 (Wiley出版化学生物学教材第四版) Fu Li, Long Yi, Lei Zhao, Aymelt Itzen, Roger S Goody, Yao-Wen Wu*, The role of the hypervariable C-terminal domain in Rab GTPases membrane targeting, Proceedings of the National Academy of Sciences 02/2014; 111(7): 2572-7 (IF: 9.423) Stephanie Voss, Lei Zhao, Xi Chen, Frank Gerhard, Yao-Wen Wu*, Generation of an intramolecular three-color fluorescence resonance energy transfer probe by site-specific protein labeling, Journal of Peptide Science 02/2014; 20(2) (IF: 1.951) Lei Zhao, Zhi-Wen Hu, Pei Tong, Yong-Xiang Chen*, Yu-Fen Zhao and Yan-Mei Li*, Addition of Artificial Salt Bridge by Ile646Lys Mutation in gp41 Coiled-Coil Domain Regulate Six-Helical Bundle Formation, Bioorg Med Chem Lett. 2013, 23(9):2727-2732 (IF: 2.486) Jing-Wen Ma, Lei Zhao, Qian Liu, De-Sheng Zhao, Yong-Xiang Chen, Chong Liu, Yu-Fen Zhao, Yan-Mei Li*, Covalently reactive group-modified peptide that specifically react with Lysine16 in Amyloid β, Chem. Commun., 2012 Sep, 48, 10565-10567 (IF: 6.567) Lei Zhao, Pei Tong, Yong-Xiang Chen , Zhi-Wen Hu , Kun Wang, Yu-Ning Zhang, De-Sheng Zhao, Li-Feng Cai, Ke-Liang Liu, Yu-Fen Zhao and Yan-Mei Li*, A multi-functional peptide as an HIV-1 entry inhibitor based on self-concentration, recognition, and covalent attachment, Org Biomol Chem. 2012 Aug 28;10(32):6512-20 (IF: 3.559) Chen YX, Zhao L, Huang ZP, Zhao YF, Li YM, Facile synthesis of cyclopeptide-centered multivalent glycoclusters with 'click chemistry' and molecular recognition study by surface plasmon resonance, Bioorg Med Chem Lett. 2009 Jul 15;19(14):3775-8 (IF: 2.486) Wu WH, Sun X, Yu YP, Hu J, Zhao L, Liu Q, Zhao YF, Li YM, TiO2 nanoparticles promote beta-amyloid fibrillation in vitro, Biochem Biophys Res Commun. 2008 Aug 22;373(2):315-8 (IF: 2.371) Chen YX, Zhao W, Zhao L, Zhao YF, Li YM, Facile synthesis of a pentasaccharide mimic of a fragment of the capsular polysaccharide of Streptococcus pneumoniae type 15C, Carbohydr Res. 2008 Mar 17;343(4):607-14 (IF: 1.817)