鲁紫东 - 华南理工大学 - 医学院（生命科学研究院）

个人简介

2016—至今华南理工大学，医学院，讲师 2012—2016 伦敦大学国王学院，药学院，博士 2010—2011 伦敦大学国王学院，药学院，硕士 2005—2010 安徽医科大学，药学院，学士

研究领域

主要从事生物医用高分子材料和纳米生物医学研究，针对癌症治疗过程中，体内递送药物遇到的关键瓶颈，对纳米药物对肿瘤微环境的调控和机制的研究，并通过优化纳米载体的纳米特性，增强药物递送效率及抗癌效果。

近期论文

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1. Cong-Fei Xu#, Zi-Dong Lu#, Ying-Li Luo, Yang Liu, Zhi-Ting Cao, Song Shen, Hong-Jun Li, Jing Liu, Kai-Ge Chen, Zhi-Yao Chen, Xian-Zhu Yang, Zhen Gu, Jun Wang*. Targeting of NLRP3 Inflammasome with Gene Editing for the Amelioration of Inflammatory Diseases. Nature Communications. 2018, 9, 4092. # (co-first author) (IF=12.353) 2. Ziyang Cao#, Yin-Chu Ma#, Chun-Yang Sun#,Zi-Dong Lu#, Ze-Yu Yao,Jun-Xia Wang, Dong-Dong Li,You-Yong Yuan,Xian-Zhu Yang*ROS-sensitive polymeric nanocarriers with red light-activated size shrinkage for remotely controlled drug release. Chemistry of Materials. 2018, 30, 517-525. # (co-first author) (IF=9.890) 3. Yang Liu#, Gui Zhao#, Cong-Fei Xu*, Ying-Li Luo, Zi-Dong Lu*, Jun Wang, Systemic Delivery of CRISPR/Cas9 with PEG-PLGA Nanoparticles for Chronic Myeloid Leukemia Targeted Therapy. Biomaterials Science. 2018, 6, 1592-1603. *(co-corresponding author) （IF=5.831） 3. Yuan-Yuan Xie#, Zi-Dong Lu#, Xiao-Le Kong, Tao Zhou, Sukhi Bansal, Robert Hider*. Systematic Comparison of the Mono-, Dimethyl- and Trimethyl 3-Hydroxy-4(1H)-Pyridones - Attempted Optimization of the Orally Active Iron Chelator, Deferiprone. European Journal of Medicinal Chemistry. 2016, 115:132-140.# (co-first author) (IF=4.816) 4. Jun-Pei Li#，Zi-Dong Lu#，Xiao-Le Kong，Yong-Min Ma, Xing-Yuan Zhang, Sukhi Bansal, Vincenzo Abbate, Robert Hider*. Design and Synthesis of Novel Pegylated Iron Chelators with Decreased Metabolic Rate. Future Medicinal Chemistry. 2015, 7: 2439-2449. #(co-first author) (IF=3.969)