杜金志 - 华南理工大学 - 医学院（生命科学研究院）

个人简介

2016.10-至今，华南理工大学，医学院、生命科学研究院，特聘研究员 2012.05-2016.09，美国埃默里大学（Emory University）医学院，博士后 2006.09-2011.12，中国科学技术大学，高分子化学与物理，博士 2002.09-2006.07，中国科学技术大学，高分子化学，学士

研究领域

实验室的研究兴趣是药物载体和递送、纳米医学、分子影像学，属材料学、生命科学和医学等多学科交叉的研究方向。课题组的研究以解决医学、生命科学等科学问题为出发点，运用纳米技术、材料学的基本方法，设计开发新型的功能纳米材料，研究其在癌症等重大疾病的检测、成像及治疗方面的应用，探索癌症诊疗新思路与新方法。

近期论文

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1. Song Shen#, Hong-Jun Li#, Kai-Ge Chen, Yu-Cai Wang, Xian-Zhu Yang, Zhe-Xiong Lian, Jin-Zhi Du*, Jun Wang*, Spatial Targeting of Tumor-Associated Macrophages and Tumor Cells with a pH-Sensitive Cluster Nanocarrier for Cancer Chemoimmunotherapy Nano Lett. 2017, 17, 3822–3829 (Top 20 most read articles in June 2017) 2. Hong-Jun Li#, Jin-Zhi Du*,#, Jing Liu, Xiao-Jiao Du, Song Shen, Yan-Hua Zhu, Xiaoyan Wang, Xiaodong Ye, Shuming Nie*, Jun Wang*, Smart Superstructures with Ultrahigh pH-Sensitivity for Targeting Acidic Tumor Microenvironment: Instantaneous Size Switching and Improved Tumor Penetration ACS Nano 2016, 10, 6753–6761 (ESI highly cited paper, Top 20 most read articles in June 2016) 3. Jin-Zhi Du, Xiao-Jiao Du, Cheng-Qiong Mao, Jun Wang*, Tailor-Made Dual pH-Sensitive Polymer-Doxorubicin Nanoparticles for Efficient Anti-Cancer Drug Delivery J. Am. Chem. Soc.2011, 133, 17560–17563 (ESI highly cited paper) 4. Jin-Zhi Du,Tian-Meng Sun, Wen-Jing Song, Juan Wu, Jun Wang*, A Tumor-Acidity-Activated Charge-Conversional Nanogel as an Intelligent Vehicle for Promoted Tumoral-Cell Uptake and Drug Delivery Angew. Chem. Int. Ed. 2010, 49, 3621–3626 (ESI highly cited paper) 5. Hong-Jun Li#, Jin-Zhi Du#, Xiao-Jiao Du#, Cong-Fei Xu, Chun-Yang Sun, Hong-Xia Wang, Zhi-Ting Cao, Xian-Zhu Yang, Yan-Hua Zhu, Shuming Nie*, Jun Wang*, Stimuli-Responsive Clustered Nanoparticles for Improved Tumor Penetration and Therapeutic Efficacy Proc. Natl. Acad. Sci. U. S. A. 2016, 113, 4164–4169 (ESI highly cited paper) 6. Jinzhi Du, Lucas A. Lane, Shuming Nie*, Stimuli-Responsive Nanoparticles for Targeting the Tumor Microenvironment J. Controlled Release 2015, 219, 205–214 7. Chun-Yang Sun#, Yang Liu#, Jin-Zhi Du#, Zhi-Ting Cao, Cong-Fei Xu, Jun Wang*, Facile Generation of Tumor-pH-Labile Linkage-Bridged Block Copolymers for Chemotherapeutic Delivery Angew. Chem. Int. Ed., 2016, 55, 1010–1014 (ESI highly cited paper) 8. Jin-Zhi Du, Cheng-Qiong Mao, You-Yong Yuan, Xian-Zhu Yang, Jun Wang*, Tumor Extracellular Acidity-activated Nanoparticles as Drug Delivery Systems for Enhanced Cancer Therapy Biotech. Adv. 2014, 32, 789–803 9. Jin-Zhi Du, Hong-Yan Long, You-Yong Yuan, Meng-Meng Song, Liang Chen, Hong Bi, Jun Wang*, Micelle-to-Vesicle Morphological Transition via Light-Induced Rapid Hydrophilic Arm Detachment from A Star Polymer Chem. Comm. 2012, 48, 1257-1259 10. Tian-Meng Sun#, Jin-Zhi Du#, Yan-Dan Yao#, Cheng-Qiong Mao, Shuang Dou, Song-Yin Huang, Pei-Zhuo Zhang, Kam W. Leong, Er-Wei Song*, Jun Wang*, Simultaneous Delivery of siRNA and Paclitaxel via a “Two-in-One” Micelleplex Promotes Synergistic Tumor Suppression ACS Nano 2011, 5, 1483–1494 (ESI highly cited paper) 11. Tian-Meng Sun#, Jin-Zhi Du#, Li-Feng Yan, Hai-Quan Mao, Jun Wang*, Self-Assembled Biodegradable Micellar Nanoparticles of Amphiphilic and Cationic Block Copolymer for siRNA Delivery Biomaterials 2008, 29, 4348–4355 (ESI highly cited paper)