个人简介
教育背景:
2000.09 - 2004.06,华中科技大学,化学工程与工艺,学士
2004.09 - 2010.03,中国科学院上海有机化学研究所,分析化学,博士
工作经历:
2011.03 - 2013.05,The University of Texas at Austin,博士后
2014.04 - 2014.09,上海 ICI 研发管理有限公司,高级研究员
2014.09 - 至今,中国海洋大学医药学院,副教授
研究领域
质谱技术用于海洋活性物质的筛选和评价
生物质谱技术在生物大分子(多糖,蛋白质及核酸等)分析研究中的应用
生物质谱和有机质谱的应用研究
近期论文
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1. Liu Tangrong#, Liu Ruonan#, Zhu Li, Zou Xuan, Guan Huashi, Xu Zhe*, Development of a UHPLC-MS method for inhibitor screening against α-L-1,3-fucosidase. Analytical and Bioanalytical Chemistry, 2019, 411(7): 1467-1477.
2. Zhu Li, Liu Ruonan, Liu Tangrong, Zou Xuan, Xu Zhe*, Guan Huashi, A novel strategy to screen inhibitors of multiple aminoglycoside-modifying enzymes with ultra-high performance liquid chromatography-quadrupole-time-of-flight mass spectrometry. Journal of Pharmaceutical and Biomedical Analysis, 2019, 164: 520-527.
3. 朱黎,邹旋,刘堂荣,刘若男,许哲*,质谱技术在酶抑制剂筛选中的研究进展. 药学学报,2019,54(5): 818-827.
4. Xu Zhe*, Liu Ruonan, Guan Huashi. Dual-target inhibitor screening against thrombin and factor Xa simultaneously by mass spectrometry. Analytica Chimica Acta, 2017, 990: 1-10.
5. Xu Zhe, Brodbelt Jennifer*. Differentiation and Distributions of DNA/Cisplatin Crosslinks by Liquid Chromatography-Electrospray Ionization-Infrared Multiphoton Dissociation Mass Spectrometry. Journal of The American Society for Mass Spectrometry, 2014, 25(1): 71-79.
5. Xu Zhe, Shaw Jared, Brodbelt Jennifer*. Comparison of MS/MS Methods for Characterization of DNA/Cisplatin Adducts. Journal of the American Society for Mass Spectrometry, 2013, 24(2): 265-273.