江涛 - 中国海洋大学

个人简介

教育背景： 1988.9 - 1993.9，中国科学院长春应用化学研究所，硕士、博士直读 1993.11 - 1995.11，香港浸会大学，化学 1995.12 - 1997.4，英国 University of Essex，药物化学，研究助理（博士后）工作经历： 1997.4 - 至今，中国海洋大学医药学院，教授 2000.12 - 至今，中国海洋大学医药学院，教授、博士生导师获奖荣誉：教育部优秀青年奖励计划获得者

研究领域

海洋天然产物如海洋生物碱杂多环的合成及其结构优化与构效关系基于蛋白质结构的药物设计与合成及生物活性研究活性分子的糖基化、磷酸酯化、硼酸化等化学修饰和基于糖结构的药物设计与合成

近期论文

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Aglycone Ebselen and β-D-Xyloside Primed Glycosaminoglycans Co-contribute to Ebselen-β-d-Xyloside-Induced Cytotoxicity, Yang Tang, Siqi Zhang, Yajing Chang, Dacheng Fan, Ariane De Agostini, Lijuan Zhang*, and Tao Jiang*, J. Med. Chem., 2018, 61 (7), 2937-2948, Wei Wang, Ruijuan Yin, Meng Zhang, Rilei Yu, Cui Hao, Lijuan Zhang*, and Tao Jiang*, Boronic Acid Modifications Enhance the Anti-Influenza A Virus Activities of Novel Quindoline Derivatives, J. Med. Chem., 2017, 60 (7), pp 2840–2852 Design and synthesis of neolamellarin a derivatives targeting heat shock protein 90, Long Jiang, Ruijuan Yin, Xueting Wang, Jiajia Dai, Jing Li, Tao Jiang*, Rilei Yu*, Euro. J. Med. Chem., 2017, 135, 24-33 Isothiouronium modification empowers pyrimidine-substituted curcumin analogs potent cytotoxicity and Golgi localization, Sheng Tong; Meng Zhang; Shixi Wang; Ruijuan Yin; Rilei Yu; Shengbiao Wan; Tao Jiang *; Lijuan Zhang *, Eur. J. Med. Chem. (2016), 123, 849-857 Pharmacokinetics in vitro and in vivo of two novel prodrugs of oleanolic acid in rats and its hepatoprotective effects against liver injury induced by CCl4, Zongjiang Yua, , Weizhi Sun, Weibing Peng, GuoqiangLi,Tao Jiang*, Molecular Pharmaceutics (2016), 13(5), 1699-1710. Design, Synthesis, and Biological Evaluation of NovelNon-Covalent Binding Quinazoline Glycoside Derivatives Targeting the Epidermal Growth Factor Receptor (EGFR) KinaseT790M/L858R Mutant, Renshuai Zhang, Shaopeng Chen, Xiaowei Zhang, Jing Ai, Shengbiao Wan, Meiyu Geng2*, Tao Jiang1*, RSC Advances, (2016), 6(43), 36857-36862. Ebselen as a potent covalent inhibitor of New Delhi metallo-β-lactamase (NDM-1), Jiachi Chiou, Shengbiao Wan, Kin-Fai Chan, Pui-Kin So, Dandan He, Edward Wai-chi Chan, Tak-hang Chan, Kwok-yin Wong, Jiang Tao* and Sheng Chen*, Chem. Commun., 2015,51, 9543-9546 Different cytotoxicities and cellular localizations of novel quindoline derivatives with or without boronic acid modifications in cancer cells, Ruijuan Yin, Meng Zhang, Cui Hao, Wei Wang, Peiju Qiu, Shengbiao Wan, Lijuan Zhang* and Tao Jiang*, ChemComm, (2013)