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个人简介

教育背景: 1989.09 - 1993.06,山东中医药大学,中药学,学士 1993.09 - 1996.06,沈阳药科大学,生药学,硕士 1999.09 - 2004.07,中国海洋大学,水产品加工与贮藏(海洋药物方向),博士 工作经历: 1996.07 - 1998.11,中国海洋大学医药学院,助教 1998.12 - 2006.11,中国海洋大学医药学院,讲师 2005.02 - 2006.02,德国杜塞尔多夫大学医药生物研究所,博士后 2006.12 - 2015.11,中国海洋大学医药学院,副教授 2015.12 - 至今,中国海洋大学医药学院,教授

研究领域

藻类中药药效物质和先导化合物的发现研究 海洋中药材的质量评价研究 海洋中药新药与保健食品的研究与开发

近期论文

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1. Weiping Ma, Haihua Li, Ming Liu* and Hongbing Liu*. Effects of simulated digestion in vitro on the structure and macrophages activation of fucoidan from Sargassum fusiforme. Carbohydrate Polymers, 2021, 272: 118484. 2. Ying Yan, ZhouminNiu, Boyang Wang, Shangge Zhao, Chao Sun, Yuting Wu, Yuying Li, Hao Ying*, and Hongbing Liu*. Saringosterol from Sargassum fusiformemodulates cholesterol metabolism and alleviates atherosclerosis in apoE-deficient mice. Mar. Drugs,2021, 19: 485. 3. PengruiWang, Jiapeng Chen, Lujing Chen, Li Shi, and Hongbing Liu*. Characteristic volatile composition of seven seaweeds from the yellow sea of China. Mar. Drugs,2021, 19: 192. 4. Weiping Ma, Shuman Hu, Yanlai Xu, Haihua Li, Xiaoqing Ma, Baohong Wei, Fuyu Li, Huashi Guan,Guangli Yu, Ming Liu*, and Hongbing Liu*. Haimufangdecoction, a Chinese medicine formula for lung cancer, arrests cell cycle, stimulates apoptosis in NCI-H1975 cells, and induces M1 polarization in RAW 264.7 macrophage cells. BMC Complement Med. Ther.,2020, 20: 243. 5. Jiapeng Chen, Hongbing Liu*. Nutritional indices for assessing fatty acids: amini-review.Int. J. Mol. Sci.,2020, 21: 5695 6. Xiuli Zhang, Cong Wang, Zhen Chen, Peiyu Zhang, Hongbing Liu*. Development and validation of quantitative 1H NMR spectroscopy for the determination of total phytosterols in the marine seaweed Sargassum. J. Agri. Food Chem.,2016, 64: 6228-6232. 7. Zhen Chen, Yibing Xu, Tao Liu, Lining Zhang, Hongbing Liu*, Huashi Guan. Comparative studies on the characteristic fatty acid profiles of four different Chinese medicinal Sargassum seaweeds by GC-MS and chemometrics. Mar. Drugs,2016, 14: 68. 8. Daoliang Wang, Abimbola Sowemimo, Yuchao Gu, Shang Gao, Hongbing Liu*, PeterProksch. Enterolacaciamine as a potential O-GlcNAcase activator from the leaves of Enterolobiumcyclocarpum. Fitoterapia, 2015, 105: 89-92. 9. Aicui Ma, Zhen Chen, Tao Wang, Ni Song, Qian Yan, Yuchun Fang, Huashi Guan, Hongbing Liu*. Isolation of the molecular species of monogalactosyldiacyl-glycerols from brown edible seaweed Sargassum horneri and their inhibitory effects on triglyceride accumulation in 3T3-L1 adipocytes. J. Agri. Food Chem.,2014, 62: 11157-11162. 10. Zhen Chen, Jiao Liu, Zhifei Fu, Cheng Ye, Renshuai Zhang, Yiyun Song, Ying Zhang, Haihua Li, Hao Ying*, Hongbing Liu*. 24(S)-Saringosterol from edible marine seaweed Sargassum fusiforme is a novel selective LXRβ agonist. J. Agri. Food Chem.,2014, 62: 6130-6137.

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