Sherburn, Michael - The Australian National University - Research School of Chemistry College of Science

个人简介

Michael Sherburn received both his BSc and PhD degrees from The University of Nottingham. He held positions at Massey University and The University of Sydney before being appointed Fellow at the Research School of Chemistry in December 2002. He has been awarded the Le Févre Memorial Prize (2006), an Erskine Fellowship (2008) and the A.J. Birch Medal of the RACI (2008). He was promoted to Professor at the Research School of Chemistry in 2011.

研究领域

Domino reactions are spectacular events in which many bonds are made and broken in a single step. The reactions hold much promise for achieving more efficient syntheses - a pressing need in times of increasing production costs and the importance of protecting the environment by reducing waste. Our research program involves the design and implementation of sequences of cycloaddition reactions, free radical reactions and transition metal-mediated reactions to prepare polycyclic molecules with important biological properties. The program also targets new ways to achieve molecular recognition, complexation and catalysis. Overall, the primary goal is to synthesise such complex molecules in a practical manner.

近期论文

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Four-Step Total Synthesis of Selaginpulvilin D M. J. Sowden, M. S. Sherburn Org. Lett. 2017, 19, 636-63. DOI: 10.1021/acs.orglett.6b03793 Preparation of an Ion with the Highest Calculated Proton Affinity: Ortho-Diethynylbenzene Dianion B. L. J. Poad, N. D. Reed, C. S. Hansen, A. J. Trevitt, S. J. Blanksby, E. G. Mackay, M. S. Sherburn, B. Chan, L. Radom Chem. Sci. 2016, 7, 6245-6250. DOI: 10.1039/C6SC01726F Direct Cross-Couplings of Propargylic Diols N. J. Green, A. C. Willis, and M. S. Sherburn Angew. Chem. Int. Ed. 2016, 55,9244 –9248. DOI: 10.1002/anie.201604527 Synthesis and Diels–Alder Reactivity of Substituted [4]Dendralenes M. F. Saglam, A. R. Alborzi, A. D. Payne, A. C. Willis, M. N. Paddon-Row, and M. S. Sherburn J. Org. Chem., 2016, 81, 1461-1475. DOI: 10.1021/acs.joc.5b02583 Multicomponent diene-transmissive Diels-Alder sequences featuring aminodendralenes S. M. Tan, A. C. Willis, M. N. Paddon-Row and M. S. Sherburn Angew. Chem. Int. Ed. 2016, 55, 3081–3085. DOI: 10.1002/anie.201510925 Discovery and Computational Rationalization of Diminishing Alternation in [n]Dendralenes M. F. Saglam, T. Fallon, M. N. Paddon-Row, and M. S. Sherburn J. Am. Chem. Soc., 2016, 138, 1022-1032. DOI: 10.1021/jacs.5b11889 A Domino Diels–Alder Approach toward the Tetracyclic Nicandrenone Framework E. G. Mackay, M. Nörret, L. S.-M. Wong, I. Louis, A. L. Lawrence, A. C. Willis, and M. S. Sherburn Org. Lett., 2105, 17, 5517–5519. DOI: 10.1021/acs.orglett.5b02412 [5]Radialene E. G. Mackay, C. G. Newton, H. Toombs-Ruane, E. J. Lindeboom, T. Fallon, A. C. Willis, M. N. Paddon-Row, and M. S. Sherburn J. Am. Chem. Soc., 2015, 137, 14653–14659. DOI: 10.1021/jacs.5b07445 Featured on the cover. Preparation and Synthetic Value of π-Bond Rich Branched Hydrocarbons M. S. Sherburn Acc. Chem. Res., 2015, 48, 1961–1970. DOI: 10.1021/acs.accounts.5b00242 Unified Total Synthesis of the Natural Products Endiandric Acid A, Kingianic Acid E, and Kingianins A, D and F S. L. Drew, A. L. Lawrence and M. S. Sherburn Chemical Science, 2015, 6, 3886 – 3890. DOI: 10.1039/C5SC00794A Total synthesis of the pseudopterosin aglycones C. G. Newton and M. S. Sherburn Nat. Prod. Rep., 2015, 32, 865-876. DOI: 10.1039/C5NP00008D Total Synthesis of Ramonanins A–D R. S. Harvey, E. G. Mackay, L. Roger, M. N. Paddon-Row, M. S. Sherburn, A. L. Lawrence Angew. Chem. Int. Ed., 2015, 54, 1795–1798. DOI: 10.1002/anie.201409818 A Combined Computational-Experimental Study of the Kinetics of Intramolecular Diels–Alder Reactions in a Series of 1,3,8-Nonatrienes.W. J. Lording, A. D. Payne, T. N. Cayzer, M. S. Sherburn, M. N. Paddon-Row Aust. J. Chem. (special issue dedicated to the memory of Dr Des Brown), 2015, 68, 230–240. DOI: 10.1071/CH14430 Pseudopterosin synthesis from a chiral cross-conjugated hydrocarbon through a series of cycloadditions C. G. Newton, S. L. Drew, A. L. Lawrence, A. C. Willis, M N. Paddon-Row, M. S. Sherburn Nat. Chem. 2015, 7, 82–86 DOI: 10.1038/nchem.2112 The Diels–Alder Reaction in Steroid Synthesis E. G. Mackay, M. S. Sherburn Synthesis, 2015, 47, 1–21 DOI: 10.1055/s-0034-1378676 Computational and Synthetic Studies with Tetravinylethylenes E. J. Lindeboom, A. C. Willis, M. N. Paddon-Row, M. S. Sherburn J. Org. Chem., 2014, 79, 11496–11507. DOI: 10.1021/jo5021294 Simple Synthetic Receptors for Aspirin T. V. Nguyen, M. S. Sherburn Chem. Eur. J., 2014, 20, 14991–14995 DOI: 10.1002/chem.201304808 Tetravinylethylene.E. J. Lindeboom, A. C. Willis, M. N. Paddon-Row, M. S. Sherburn Angew. Chem. Int. Ed. 2014, 53, 5440-5443 DOI: 10.1002/anie.201402840 Furanodendralenes.T. Fallon, A. C. Willis, M. N. Paddon-Row, M. S. Sherburn J. Org. Chem. 2014, 79, 3185-3193 DOI: 10.1021/jo500458y Total Synthesis and Structural Revision of the Alkaloid Incargranine B.P. D. Brown, A. C. Willis, M. S. Sherburn, A. L. Lawrence Angew. Chem. Int. Ed. 2013, 52, 13273-13275 DOI: 10.1002/anie.201307875