黄思罗 - 华中科技大学 - 生命科学与技术学院

个人简介

教育经历 1991-1995年武汉大学生命科学院遗传学专业学士 2002-2009年华中科技大学生命科学与技术学院生物物理学专业博士工作经历 2009-2011年华中科技大学生命科学与技术学院博士后 2009-2010年美国密歇根大学生命科学院访问学者 2011-至今讲师

研究领域

主要研究以C 族G蛋白偶联受体和酪氨酸激酶受体为代表的跨膜蛋白的结构、功能和偶联的信号通路，以及以该类膜蛋白为靶点的抗神经系统退行性疾病和抗肿瘤药物的设计和筛选，以及相应的药物筛选方法、模型的设计和优化。

近期论文

查看导师新发文章（温馨提示：请注意重名现象，建议点开原文通过作者单位确认）

1. Zhongyong Zhang, Li Xue, Hui Guo, Ying Li, Haili Ding, Siluo Huang*. Phosphorylation-independent desensitization of Metabotropic Glutamate Receptor 5 by G Protein-coupled Receptor Kinase2 in HEK 293 cells. Mol Bio, 2013, (47): 137-46. 2. Guillaume Antony Baloucoune, Lei Chun, Wenhua Zhang, Chanjuan Xu, Siluo Huang, Yunyun Wang, Haijun Tu, Jianfeng Liu*. GABAB Receptor subunit GB1 at the cell surface independently activates ERK1/2 through IGF-1R transactivation. Plos One , 2012, 7(6): e39698. 3. Siluo Huang, Jianghua Cao, Ming Jiang, Gilles Labesse, Jean-Philippe Pin*, Jianfeng Liu*, Philippe Rondard*. Interdomain movements in metabotropic glutamate receptor activation. Proc Natl Acad Sci U S A., 2011, 108(37):15480-5. 4. Ming Jiang, Handong Ouyang, Pin Ruan, Han Zhao, Zhenjun Pi, Siluo Huang*, Ping Yi*, Michel Crepin. The chitosan derivatives inhibit cell proliferation and induce apoptosis in breast cancer cells. Anticancer Res., 2011, 31(4):1321-8. 5. Jianhua Cao#, Siluo Huang#, Ji Qian, Jinlin Huang, Li Jin, Zhixi Su, Ji Yang, Jianfeng Liu*. Evolution of the class C GPCR Venus flytrap modules involved positive selected functional divergence. BMC Evo. Bio., 2009, 9:67. 6. Arnaud Ahier, Philippe Rondard, Nadège Gouignard, Naji Khayath1, Siluo Huang, Jacques Trolet, Daniel J.Donoghue, Monique Gauthier, Jean-Philippe Pin, Colette Dissous. A new family of Receptor Tyrosine Kinases with a Venus Flytrap binding domain in insects and other invertebrates activated by aminoacids. Plos One, 2009, 4(5): e5651. 7. Philippe Rondard#, Siluo Huang#, Carine Monnier, Haijun Tu, Bertrand Blanchard, Nadia Oueslati, Fanny Malhaire, Ying Li, Eric Trinquet, Gilles Labesse, Jean-Philippe Pin*, Jianfeng Liu*. Functioning of the dimeric GABAB receptor extracellular domain revealed by glycan wedge scanning. EMBO J., 2008, 27:1321-32. 8. Philippe Rondard#,*, Jianfeng Liu#,*, Siluo Huang, Fanny Malhaire, Claire Vol, Alexia Pinault, Gilles Labesse, Jean-Philippe Pin. Coupling of agonist binding to effector domain activation in metabotropic glutamate-like receptors. J. Biol. Chem , 2006, 281: 24653-61.