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个人简介

1987 年获华西医科大学药物化学学士学位 2003 年获湖北大学有机化学硕士学位 1987 年 -1994 年,湖北药检高等专科学校药学系任教 1994 年 -1997 年,武汉化工学院精细化工系任教 1997 年 -2008 年,湖北中医学院药学院任教 2008 年 - 至今,华中科技大学生命科学与技术学院

研究领域

药剂学,药物化学。进行新型纳米制剂技术与纳米载药系统的研究。包括载体材料的合成、纳米载药系统的构建、纳米药物生物药剂学等

近期论文

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1. Zhao, XZ; Mou, DS; Wan, JL, et al. A novel method for the separation and determination of non-encapsulated pyrene in plasma and its application in pharmacokinetic studies of pyrene-loaded MPEG-PLA based nanoparticles . NANOTECHNOLOGY,2009,20( 12):125701. (IF=3.31) 2. Wang, W; Xiong, W; Wan, JL, et al. The decrease of PAMAM dendrimer-induced cytotoxicity by PEGylation via attenuation of oxidative stress. NANOTECHNOLOGY, 2009, 20(10): 105103. (IF=3.31) 3. Zhao, XZ; Wan, JL; Xu, HB, et al. An improved HPLC method with fluorescence detection for the determination of pyrene in rat plasma and its pharmacokinetics, JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS. 2008, 48( 4): 1237-1242. (IF=2.761) 4. Yi, T; Wan, JL; Xu, HB, et al. A new solid self-microemulsifying formulation prepared by spray-drying to improve the oral bioavailability of poorly water soluble drugs. EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS, 2008, 70(2): 439-444. (IF=3.31) 5. Chen, HB; Wan, JL; Wang, YR, et al. A facile nanoaggregation strategy for oral delivery of hydrophobic drugs by utilizing acid-base neutralization reactions. NANOTECHNOLOGY, 2008, 19(37): 375104. (Co-first authors with equal contribution) ( IF=3.31 ) 6.Yi, T; Wan, JL; Xu, HB, et al. Controlled poorly soluble drug release from solid self-microemulsifying formulations with high viscosity hydroxypropylmethylcellulose. EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES. 2008, 34( 4-5): 274-280. (IF=3.127) 7. Chen, F; Wan, JL; Guan, CS, et al. Tetrabutylammonium peroxydisulfate in organic synthesis .3. An efficient procedure for the selective oxidation of sulfides to sulfoxides by tetrabutylammonium peroxydisulfate. SYNTHETIC COMMUNICATIONS. 1996, 26( 2): 253-260. (IF=0.977)

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