个人简介
1999年6月毕业于西北大学化学化工学院化工工艺专业,获工学学士学位;2007年6月毕业于西北农林科技大学植保学院农药学专业,获农学硕士学位;2014年6月毕业于西北农林科技大学生命科学学院植物学专业,获理学博士学位。
研究领域
具有重要生物活性的天然产物分离、结构鉴定及构效关系研究; 天然活性分子类似物的设计、合成及其药理活性研究。
近期论文
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Fang-Jun Cao, Li-Fei Zhu, Qian Kuang, Xing-Qiang Li, Bo-Hang Zhou, Xin-Juan Yang*, Le Zhou. Cytotoxic activity, apoptosis induction and structure–activity relationship of 8-OR-2-aryl -3,4-dihydroisoquinolin-2-ium salts as promising anticancer agents. Bioorganic & Medicinal Chemistry Letters. 2017, 27, 55–60. Yang XJ, Yao Y, Qin YY, Hou Z, Yang R, Miao F, Zhou L. Synthesis and in Vitro Antifungal Activities of New 2-Aryl-6,7-methylenedioxy -3,4-dihydro isoquinolin-2-ium Bromides. Chem. Pharm. Bull. 2013, 61(7): 731-739. Yang XJ, Miao F, Yao Y, Cao FJ, Yang R, Ma YN, Qin BF, Zhou L. In vitro antifungal activity of sanguinarine and chelerythrine derivatives against phytopathogenic fungi. Molecules . 2012, 17 : 13026-13035. Hou Z, Yang R, Zhang C, Zhu LF, Miao F, Yang XJ*, Zhou L. 2-(Substituted phenyl)- 3,4- dihydroisoquinolin-2-iums as Novel Antifungal Lead Compounds: Biological Evaluation and structure- Activity Relationships. Molecules , 2013, 18: 10413-10424. Miao F, Yang R, Chen DD, Wang Y, Qin BF, Yang XJ*, Zhou L. Isolation, Identification and Antimicrobial Activities of Two Secondary Metabolites of Talaromyces verruculosus. Molecules 2012, 17 : 14091-14098. Ma YN, Yang XJ, Pan L, Hou Z, Geng HL, Song XP, Zhou L, Miao F. Synthesis of 2-Aryl-3,4-dihydroisoquinolin-2-ium bromides and their in vitro acaricidal activity against psoroptes cuniculi . Chem . Pharm . Bull . 2013, 61 (2): 204-211. Miao F, Yang XJ, Ma YN, Zheng F, Song XP, Zhou L. Structural modification of sanguinarine and chelerythrine and their in vitro acaricidal activity against Psoroptes cuniculi . Chem . Pharm . Bull . 2012, 60 (12): 1508-1513. Zhang, Wen; Sui, Guoqing; Li, Yulin; Fang, Mei; Yang, Xinjuan; Ma, Xihan; Zhou, Wenming.Synthesis and in vitro antifungal activities of novel benzamide derivatives containing a triazole moiety.Chemical & Pharmaceutical Bulletin (2016), 64(6), 616-624