刘北明 - 中国科学技术大学 - 合肥微尺度物质科学国家研究中心

个人简介

EDUCATION AND RESEARCH EXPERIENCE 1985 - 1989 B.S. (Physics), Peking University 1989 - 1992 M.S. program (Physics), University of Hong Kong 1993 - 1999 Ph.D. (Molecular and Cell Biology), University of California at Berkeley 1999 - 2000 Postdoctoral Fellow, University of California at San Diego 2000 - 2006 Research Associate, University of Pittsburgh School of Medicine 2006 - 2008 Research Assistant Professor, University of Pittsburgh School of Medicine 2009 - Professor, University of Science and Technology of China

研究领域

1. Synaptic development and plasticity 2. Neural network dynamics and learning 3. Stress and related diseases 4. Brain mapping techniques

近期论文

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1. Xu C, Liu H-J, Qi L, Tao C-L, Wang Y-J, Shen Z, Tian C-L, Lau P-M* & Bi G-Q*. Structure and plasticity of silent synapses in developing hippocampal neurons visualized by super-resolution imaging. Cell Discovery 6, 1-11 (2020). 2. Wang H, Zhu Q, Ding L, Shen Y, Yang C-Y, Xu F, Shu C, Guo Y, Xiong Z, Shan Q, Jia F, Su P, Yang Q-R, Li B, He X, Chen X, Wu F, Zhou J-N, Xu F, Han H, Lau P-M* & Bi G-Q*. Scalable volumetric imaging for ultrahigh-speed brain mapping at synaptic resolution. National Science Review 6, 982-992 (2019). 3. Liu YT, Tao CL, Lau PM, Zhou ZH & Bi GQ. Postsynaptic protein organization revealed by electron microscopy. Curr Opin Struct Biol 54, 152-160 (2019). 4. Guo Y, Tang X, Zhang J, Jin S, Li J, Ding L, Zhang K, Yang C, Zhou H, He X, Xu F, Bi GQ, Xu L & Lau PM. Corticosterone Signaling and a Lateral Habenula-Ventral Tegmental Area Circuit Modulate Compulsive Self-Injurious Behavior in a Rat Model. J Neurosci 38, 5251-5266 (2018). 5. Zhang JC, Lau PM & Bi GQ. Gain in sensitivity and loss in temporal contrast of STDP by dopaminergic modulation at hippocampal synapses. Proc Natl Acad Sci U S A 106, 13028-13033 (2009). 6. Lau P & Bi G. Reverberatory activity in neuronal networks in vitro. Chinese Science Bulletin 54, 1828-1835 (2009). 7. Lau PM & Bi GQ. Synaptic mechanisms of persistent reverberatory activity in neuronal networks. Proc Natl Acad Sci U S A 102, 10333-10338 (2005). 8. Lau PM, Zucker RS & Bentley D. Induction of filopodia by direct local elevation of intracellular calcium ion concentration. J Cell Biol 145, 1265-1275 (1999).