丁勇 - 中国科学技术大学

个人简介

丁勇中国科学技术大学生命科学院教授、博士生导师。1997年毕业于安徽农业大学获学士学位；2007年获中国科学院遗传与发育生物学研究所博士学位；2007-2010年分别在西南医学中心和内布拉斯加大学从事博士后研究工作；2011年1月-2012年8月在内布拉斯加大学任研究助理教授 (Research Assistant Professor)；2012年9月任职至今。丁勇研究组长期从事植物组蛋白修饰分子调控机制的研究，以组蛋白修饰调控基因转录和植物生长发育进程为重点。自2012年回国建立实验室以来，系统解析了植物组蛋白H3第4位赖氨酸三甲基化 (H3K4me3) 有别于哺乳动物的独特调控方式；发现了植物组蛋白特有的H2A第95位丝氨酸磷酸化 (H2AS95ph) 修饰及其调控的全新机制；首次报道植物“干旱记忆”和“转录记忆”及其表观调控；揭示了长非编码RNA调控组蛋白27位赖氨酸三甲基化 (H3K27me3) 的内在机制。上述研究延伸并拓展了组蛋白修饰的生物学内涵，揭示了植物组蛋白修饰位点和调控方式的独特性，提示了植物组蛋白修饰研究的重要性和必要性。相关研究成果发表在Science Advances、The Plant Cell、PNAS、Nature Communications、PLoS Genetics、New Phytologist、Plant Physiology、Plant Journal等学术期刊上，多篇文章被Faculty 1000推荐，以及被Cell和Plant Cell等杂志评述。

研究领域

组蛋白修饰建立和维持的分子机制组蛋白修饰调控调节植物生长发育和基因转录的分子机制组蛋白修饰与环境应答

近期论文

查看导师新发文章（温馨提示：请注意重名现象，建议点开原文通过作者单位确认）

Tiang Y#, Zheng H#, Zhang F#, Wang S, Ji X, Xu C, He Y, Ding Y*. PRC2 recruitment and H3K27me3 deposition at FLC require FCA binding of COOLAIR. Science Advances. 2019 24;5(4):eaau7246. F1000 comments:https://f1000.com/prime/735606638 Jiang P, Wang S, ZhengH, Li H, Zhang F, Su Y , Xu Z, Lin H , Qian Q, Ding Y*. SIP1 participates in regulation of flowering time in rice by recruiting OsTrx1 to Ehd1. New Phytologist. 2018. 219(1):422-435. Jiang P, Wang S, Jiang H, Cheng B, Wu K, Ding Y*. The COMPASS-like complex promotes flowering and panicle branching in rice. Plant Physiology. 2018. 176(4):2761-2771. Jiang P, Wang S, Ikram A, Xu Z Jiang H, Cheng B*, Ding Y*.SDG721 and SDG705 are required for rice growth. Journal of Integrative Plant Biology.2018. 60(7):530-535. (Cover story) Zheng H,Zhang F,Wang S,Su Y, Ji X, Jiang P, Chen R, Hou S, Ding Y*.MLK1 and MLK2 coordinate RGA and CCA1 activity to regulate hypocotyl elongation in Arabidopsis thaliana. Plant Cell. 2018 30 (1): 67-82. Zheng H, Ding Y*. MLK1 and MLK2 integrate gibberellins and circadian clock signaling to modulate plant growth. Plant signaling & behavior.2018. 13(2):e1439654. Su Y, Wang S, Zhang F, Zheng H, Liu Y, Huang T, Ding Y*. Phosphorylation of histone H2A at serine 95: A plant-specific mark involved in flowering time regulation and H2A.Z deposition. Plant Cell.2017 29 (9): 2197-2213. Highlighted in Brief: Know Your histone (zip) code: flowering time and phosphorylation of histone H2A on serine 95. Plant Cell. 2017 29 (2): 2084-2085. Lu C#, Tian Y#, Wang S, Su Y, Mao T, Huang T, Chen Q, Xu Z, Ding Y*. Phosphorylation of SPT5 by CDKD;2 is required for VIP5 recruitment and normal flowering in Arabidopsis thaliana. Plant Cell. 2017 29 (2): 277-291. Ding Y, Virlouvet L, Liu N, Riethoven JJ, Fromm M, Avramova Z. Dehydration stress memory genes of Zea mays; comparison with Arabidopsis thaliana. BMC Plant Biololgy. 2014 14:141. Ding Y, Liu N, Virlouvet L, Riethoven JJ, Fromm M, Avramova Z. Four distinct types of dehydration stress memory genes in Arabidopsis thaliana. BMC Plant Biololgy. 2013 13:229. Song Z, Sun L, Lu S, Tian Y, Ding Y, Liu J. Transcription factor interaction with COMPASS-like complex regulates histone H3K4 trimethylation for specific gene expression in plants. PNAS. 2015 112(9):2900-5. Virlouvet L, Ding Y, Liu N, Avramova Z, Fromm M. ABA Signaling is necessary but not sufficient for RD29B transcriptional memory during successive dehydration stresses in Arabidopsis thaliana. The Plant Journal. 2014 79(1):150-61. Liu N, Ding Y, Fromm M, Avramova Z. Different gene-specific mechanisms determine the ‘revised-response’ memory transcription patterns of a subset of A. thaliana dehydration stress responding genes. Nucleic Acids Research. 2014 42 (9): 5556-66. Ding Y, Ndamukong I, Xu Z, Lapko H, Fromm M, Avramova Z. ATX1-generated H3K4me3 Is required for efficient elongation of transcription, not Initiation, at ATX1-regulated genes. PLoS Genetics. 2012 8 (12):e100311.