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个人简介

1983-1987,日本东京工业大学,化学工程系,工科学士 指导教授:Takeshi Nakai教授; 1987-1989,日本东京工业大学,化学工程系,工科硕士 指导教授:Takeshi Nakai和Kochi Mikami教授; 1989-1994,美国哈佛大学,化学系,博士 指导教授:E. J. Corey教授

研究领域

绿色化学;不对称有机合成反应;生物质分子的有机转化;有机合成化学新反应、新概念的研究;具有生物活性的复杂天然产物和人工分子的合成研究。

近期论文

查看导师新发文章 (温馨提示:请注意重名现象,建议点开原文通过作者单位确认)

1)Xiao, J.; Lu, Y. P.; Liu, Y. L.; Wong, P. S.; Loh, T. P. A New Class of Structurally Rigid Tricyclic Chiral Secondary Amine Organocatalyst: Highly Enantioselective Organocatalytic Michael Addition of Aldehydes to Vinyl Sulfones. Org. Lett. 2011, 13, 876-879. 2)Wang, P.; Yeo, X. L. Loh, T. P. Copper-Catalyzed Highly Regioseletive Silylcupration of Teminal Alkynes to Forma-Vinylsilanes J. Am. Chem. Soc. 2011, 133, 1254-1256. 3)Shen, Z. L.; Goh, K. K. K.; Yang, Y. S.; Wong, Y. C.; Loh, T. P. Direct Synthesis of Water-Tolerant Alkyl Indium Reagents and Their Application in Palladium-Catalyzed Coupling with Aryl Halides Angew. Chem. Int. Ed. 2011, 50, 511-514. 4)Feng, C.; Loh, T. P.Palladium-Catalyzed Bisolefination of C-C Triple Bonds: A Facile Method for the Synthesis of Naphthalene Derivatives J. Am. Chem. Soc. 2010, 132, 17710-17712. 5)Shen, Z. L.; Goh, K. K. K.; Cheong, H. L.; Wong, Y. C.; Loh, T. P. Synthesis of Water-Tolerant Indium Homoenolate in Aqueous Media and Its Application in the Synthesis of 1,4-Dicarbonyl Compounds via Palladium-Catalyzed Coupling with Acid Chloride J. Am. Chem. Soc. 2010, 132, 15852-15855. 6)Wang, S. Y.; Song, P.; Chan, L. Y.; Loh, T. P. Total Synthesis of Phytophthora Mating Hormone a1. Org. Lett. 2010, 12, 5166-5169. 7)Wang, S. Y.; Loh, T. P. Highly Enantioselective Cu(I)-Tol-BINAP-catalyzed Asymmetric Conjugate Addition of Grignard Reagents to a,b-Unsaturated Esters. Chem. Commun. 2010, 46, 8694-8703. 8)Sampath, M.; Loh, T. P. Highly Enantio-, Regio- and Diastereo-selective One-pot [2+3]-Cycloaddition Reaction via Isomerization of 3-Butynoates to Allenoates. Chem. Sci. 2010, 1, 739-742. 9)Zhao, Y. J.; Li, B.; Tan, L. J. S.; Shen, Z. L.; Loh, T. P. Enantioselective Cationic Polyene Cyclization vs Enantioselective Intramolecular Carbonyl-Ene Reaction. J. Am. Chem. Soc. 2010, 132, 10242-10244. 10)Alam, J.; Keller, T. H.; Loh, T. P. Functionalization of Peptides and Proteins by Mukaiyama Aldol Reaction. J. Am. Chem. Soc. 2010, 132, 9546-9548. 11)Zhu, M. K.; Zhao, J. F.; Loh, T. P. Palladium-Catalyzed Oxime Assisted Intramolecular Dioxygenation of Alkenes with 1 atm of Air as the Sole Oxidant. J. Am. Chem. Soc. 2010, 132, 6284-6285.

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