个人简介
EDUCATION AND RESEARCH EXPERIENCE
09/1998 - 06/2002 B.S., Anhui University, China
09/2002 - 06/2007 Ph.D, University of Science & Technology of China
08/2007 - 02/2011 Postdoc, Ludwig Institute for Cancer Research, Lausanne Branch, Switzerland
03/2011 - present Professor, University of Science & Technology of China
研究领域
1. Molecular mechanisms of activation and regulation of the pattern recognition receptors (PRRs).
2. How the gut flora controls the intestinal homeostasis, especially the role of pattern recognition receptors (PRRs) in this process.
3. Function and development of the intestinal intraepithelial lymphocytes (IELs).
近期论文
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1. Commensal viruses maintain intestinal intraepithelial lymphocytes via noncanonical RIG-I signaling. Liu L, Gong T, Tao W, Lin B, Li C, Zheng X, Zhu S*, Jiang W*, Zhou R*. Nat Immunol. 2019 Dec;20(12):1681-1691.
2. DAMP-sensing receptors in sterile inflammation and inflammatory diseases. Gong T, Liu L, Jiang W*, Zhou R*. Nat Rev Immunol. 2020 Feb;20(2):95-112.
3. TRIM65-catalized ubiquitination is essential for MDA5-mediated antiviral innate immunity. Lang X, Tang T, Jin T, Ding C*, Zhou R*, Jiang W*. J Exp Med. 2017 Feb;214(2):459-473.
4. CLICs-dependent chloride efflux is an essential and proximal upstream event for NLRP3 inflammasome activation. Tang T, Lang X, Xu C, Wang X, Gong T, Yang Y, Cui J, Bai L, Wang J, Jiang W*, Zhou R*. Nat Commun. 2017 Aug 4;8(1):202.
5. Dopamine controls systemic inflammation through inhibition of NLRP3 inflammasome. Yan Y#, Jiang W#, Liu L, Wang X, Ding C, Tian Z*, Zhou R*. Cell. 2015 Jan 15;160(1-2):62-73.