个人简介
1979年毕业于宁夏医学院医疗系,1985年宁夏医学院硕士学位毕业,1996年荷兰 Amsterdam 大学医学院博士学位毕业,1996-1998荷兰皇家科学院脑研究所博士后。在 NATURE 等 SCI 期刊发表论文100余篇。他人引用5600余篇次,H 因子41。2014-2018年连续入选爱思唯尔-神经科学高被引学者榜单。现任中国科大生命学院教授,中科院脑功能和脑疾病重点实验室主任。兼任安徽省神经科学学会理事长。
研究领域
1. 抑郁症的发病机制和诊治基础
2. 阿尔茨海默氏病的分子影像探针
主要在研课题
科技部重点研发专项,基金委重大计划项目,中科院B类先导项目。
近期论文
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1. Chen P, Lou S, Huang ZH, Wang Z, Shan QH, Wang Y, Yang Y, Li X, Gong H, Jin Y, Zhang Z, Zhou JN. Prefrontal Cortex Corticotropin-Releasing Factor Neurons Control Behavioral Style Selection under Challenging Situations. Neuron. 2020 Feb 5. pii: S0896-6273(20)30060-X. doi: 10.1016/j.neuron. 2020.01.033.
2. Zhou W, Jin Y, Meng Q, Zhu X, Bai T, Tian Y, Mao Y, Wang L, Xie W, Zhong H, Zhang N, Luo MH, Tao W, Wang H, Li J, Li J, Qiu BS, Zhou JN, Li X6 Xu H, Wang K, Zhang X, Liu Y, Levin GR, Xu L, Zhang Z*. A neural circuit for comorbid depressive symptoms in chronic pain. Nat Neurosci. 2019 Aug 26. doi: 10.1038/s41593-019-0468-2.
3. Shao W, Zhang SZ, Tang M, Zhang XH, Zhou Z, Yin YQ, Zhou QB, Huang YY, Liu YJ, Wawrousek E, Chen T, Li SB, Xu M, Zhou JN, Hu G, Zhou JW. 2013. Suppression of neuroinflammation by astrocytic dopamine D2 receptors via αB-crystallin. Nature. 494(7435):90-4.
4. Chen XN, Meng QY, Bao AM, Swaab DF, Wang GH, Zhou JN. 2009. The involvement of retinoic acid receptor-alpha in corticotropin-releasing hormone gene expression and affective disorders. Biol Psychiatry. 66(9):832-9.
5. Wang SS, Willem Kamphuis, Inge Huitinga, Zhou JN, D.F. Swaab.2008. Gene Expression Analysis in the Human Hypothalamus in Depression by Laser Micro-Dissection and Real Time PCR: the presence of multiple receptor imbalances. Molecular Psychiatry. 13(8):786-99.
6. Zhu DF, Wang ZX, Zhang DR, Pan ZL, He S, Hu XP, Chen XC, Zhou JN. 2006. fMRI revealed neural substrate for reversible working memory dysfunction in subclinical hypothyroidism. Brain. 129(11):2923-30.
7. Bao AM, Fischer DF, Wu YH, Hol EM, Balesar R, Unmehopa UA, Zhou JN, Swaab DF. 2006. A direct androgenic involvement in the expression of human corticotropin-releasing hormone. Molecular Psychiatry. 11(6):567-76.
8. Bao AM, Hestiantoro A, Van Someren EJ, Swaab DF, Zhou JN. 2005. Colocalization of corticotropin-releasing hormone and oestrogen receptor-alpha in the paraventricular nucleus of the hypothalamus in mood disorders. Brain. 128(6):1301-13.
9. Zhou JN, Riemersma RF, Unmehopa UA, Hoogendijk WJ, van Heerikhuize JJ, Hofman MA, Swaab DF. 2001. Alterations in arginine vasopressin neurons in the suprachiasmatic nucleus in depression. Arch Gen Psychiatry. 58(7):655-62.
10. Zhou JN, Hofman MA, Gooren LJ, Swaab DF. 1995.A sex difference in the human brain and its relation to transsexuality. Nature. 378(6552):68-70.