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个人简介

涂晓明,博士,副教授,博士生导师,男,合肥微尺度物质科学国家研究中心,中国科学技术大学生命科学学院。 2012年获中国科学院卢嘉锡青年人才奖。共发表SCI论文39篇,其中以第一作者或通讯作者在Molecular Biology of the Cell,Journal of Cell Science,Journal of Biological Chemistry,Biochemical Journal,Scientific Reports等重要国际学术期刊发表研究论文29篇。

研究领域

1. 锥体虫基因表达调控和细胞周期调控的分子机制研究; 2. Ubiquitin家族蛋白的结构和功能的研究; 3. 重要蛋白或蛋白结构域的结构和功能的研究。

在研科研项目 1. 国家重大科学研究计划项目(973)子课题, 执行期限:2009-2013年,课题负责人; 2. 中国科学院“生命科学领域优秀青年科技专项”,执行期限:2011-2013年,项目负责人; 3. 国家自然科学基金面上项目,执行期限:2013-2016年,项目负责人; 4. 国家自然科学基金联合基金项目,执行期限:2014-2016年,项目负责人。

近期论文

查看导师最新文章 (温馨提示:请注意重名现象,建议点开原文通过作者单位确认)

1. Shanhui Liao, Wen Zhang, Kai Fan, Kaiqin Ye, Xuecheng Zhang, Jiahai Zhang, Chao Xu and Xiaoming Tu* (2013). Ionic strength-dependent conformations of a ubiquitin-like small archaeal modifier protein (SAMP2) from Haloferax volcanii. Scientific Reports. 3, 2136. (*通讯作者) 2. Tao Wang, Jiahai Zhang, Xuecheng Zhang, Chao Xu and Xiaoming Tu* (2013). Solution structure of the Big domain from Streptococcus pneumoniae reveals a novel Ca2+-binding module. Scientific Reports. 3, 1079. 3. Yu Qiu, Wen Zhang, Chen Zhao, Yan Wang, Weiwei Wang, Jiahai Zhang, Zhiyong Zhang, Guohong Li, Yunyu Shi, Xiaoming Tu* and Jihui Wu* (2012) Solution structure of Pdp1 PWWP domain reveals its unique binding sites for methylated H4K20 and DNA. Biochemical Journal. 442: 527-538. 4. Wen Zhang, Jiahai Zhang, Xuecheng Zhang, Chao Xu and Xiaoming Tu* (2011) Solution structure of Taf14 YEATS domain and its roles in cell growth of Saccharomyces cerevisiae. Biochemical Journal. 436: 83-90. 5. Shanhui Liao, Qiang Shang, Xuecheng Zhang, Jiahai Zhang, Chao Xu, Xiaoming Tu* (2009) Pup, a prokaryotic ubiquitin-like protein, is an intrinsically disordered protein. Biochemical Journal. Accelerated Publication. 422: 207-215. 6. Xiaoming Tu, Praveen Kumar, Ziyin Li and Ching C. Wang (2006) An Aurora Kinase Homologue is Involved in Mitosis and Cytokinesis in Trypanosoma brucei. J. Biol. Chem. 281:9677-9687. 7. Xiaoming Tu, Joel Mancuso, W. Zacheus Cande and Ching C. Wang (2005) Distinct cytoskeletal modulation and regulation of G1-S transition in the two life stages of Trypanosoma brucei. Journal of Cell Science. 118:4353-4364. 8. Xiaoming Tu and Ching C. Wang (2005) Coupling of Posterior Cytoskeletal Morphogenesis to the G1/S Transition in the Trypanosoma brucei Cell Cycle. Molecular Biology of the Cell. 16:97-105. 9. Xiaoming Tu and Ching C. Wang (2004) The involvement of two cdc2-related kinases (CRKs) in Trypanosoma brucei cell cycle regulation and the distinctive stage-specific phenotypes caused by CRK3 depletion. J. Biol. Chem. 279:20519-20528.

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