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个人简介

2018.03 - 至今 特任教授,博士生导师,合肥微尺度物质科学国家研究中心 2017.02-2018.02 特任研究员,中国科学技术大学,合肥微尺度物质科学国家研究中心 2013.08-2017.01 博士后,德国明斯特大学 2007.09-2013.06 博士,中国科学技术大学 2003.08-2007.06 学士,中国科学技术大学

研究领域

不对称电化学反应、联合催化、天然产物全合成。以新型不对称催化研究为基础提高反应活性与选择性,并将这些方法学用于天然产物的合成,发展高效、原子经济性和环境友好的现代有机合成化学

近期论文

查看导师新发文章 (温馨提示:请注意重名现象,建议点开原文通过作者单位确认)

Enantioselective electrocatalysis for the cross-dehydrogenative heteroarylation of indoles, pyrroles, and furans Liang, K.; Li, N.; Liu, M; Song, J.; Guo, C.* Angew. Chem. Int. Ed. 2024, 63, e202415723 Enantioselective nickel-electrocatalyzed reductive propargylic carboxylation with CO2 Hu, Q.; Wei, B.; Wang, M.; Liu, M.; Chen, X.-W.; Ran, C.-K.; Wang, G.; Chen, Z.; Li, H.; Song, J.; Yu, D.-G.*; Guo, C.* J. Am. Chem. Soc. 2024, 146, 14864–14874 Enantioselective nickel-catalyzed anodic oxidative dienylation and allylation reactions Zhang, Q.; Zhang, J.; Zhu, W.; Lu, R.; Guo, C.* Nat. Commun. 2024, 15, 4477 Dual-catalyzed stereodivergent electrooxidative homocoupling of benzoxazolyl acetate Zhang, J.; Zhu, W.; Chen, Z.; Zhang, Q.; Guo, C.* J. Am. Chem. Soc. 2024, 146, 1522 Ni/Cu dual-catalyzed propargylation for the stereodivergent synthesis of Methohexital Chang, X.*; Zhang, J.; Cheng, X.; Lv, X.; Guo, C.* Adv. Sci. 2024, 2406764 Dynamic kinetic stereodivergent transformations of propargylic ammonium salts via dual nickel and copper catalysis Geng, R.; Peng, L.*; Guo, C.* Chin. Chem. Lett. 2024, 35, 109433 Confluence of asymmetric catalysis and electrosynthesis in sustainable chemical transformations (Perspectives)Zhang, Q.; Liang, K.; Guo, C.* Sci. China Chem. 2024, 67, 755-758 Enantio- and diastereodivergent N-heterocyclic carbene/nickel dual-catalyzed umpolung propargylic substitutions of enals Peng, L.; Wang, M.; Guo, C.;* Gong, L-Z.;* Song, J.* J. Am. Chem. Soc. 2023, 145, 28085 Catalytic stereodivergent allylic alkylation of 2-acylimidazoles for natural product synthesis Lu, R.; Zhang, Q.; Guo, C.* Nat. Commun. 2023, 14, 8118 Enantioselective nickel-catalysed electrochemical cross-dehydrogenative amination Liang, K.; Zhang, Q.; Guo, C.* Nat. Synth. 2023, 2, 1184 Cu-catalyzed asymmetric regiodivergent electrosynthesis and its application in the enantioselective total synthesis of (-)-fumimycin Xie, T.; Huang, J.; Li, J.; Peng, L., Song, J.; Guo, C.* Nat. Commun. 2023, 14, 6749 Platinum/copper dual-catalyzed asymmetric vinylogous addition reactions for the synthesis of functionalized indoles Hu, Q.; Guo, C.* Angew. Chem. Int. Ed. 2023, 62, e202305638 Xu, X.; Wang, M.; Peng, L.; Guo, C.* Nickel-catalyzed asymmetric propargylation for the synthesis of axially chiral 1,3-disubstituted allenes. J. Am. Chem. Soc. 2022, 144, 21022―21029. Zhang, J.; Chang, X.; Xu, X.; Wang, H.; Peng, L.; Guo, C.* Nickel-catalyzed switchable 1,3-dienylation and enantioselective allenylation of phosphine oxides. Nat. Commun. 2022, 13, 7049. Liang, K.; Zhang, Q.; Guo, C.* Nickel-catalyzed switchable asymmetric electrochemical functionalization of alkenes. Sci. Adv. 2022, 8, eadd7134. Zhang, Q.; Liang, K.; Guo, C.* Enantioselective nickel-catalyzed electrochemical radical allylation. D. Angew. Chem. Int. Ed. 2022, 61, e202210632. He, Z.; Peng, L.; Guo, C.* Catalytic stereodivergent total synthesis of amathaspiramide D. Nat. Synth. 2022, 1, 393-400. Hu, Q.; He, Z.; Peng, L.; Guo, C.* Combining nickel and squaramide catalysis for the stereodivergent α-propargylation of oxindoles. Nat. Synth. 2022, 1, 322-331. Xu, X.; Peng, L.; Chang, X.; Guo, C.* Ni/Chiral Sodium Carboxylate Dual Catalyzed Asymmetric O-Propargylation. J. Am. Chem. Soc. 2021, 143, 21048-21055. Peng, L.; Wang, H.; Guo, C.* Copper-Catalyzed Enantioselective Difluoromethylation of Amino Acids via Difluorocarbene. J. Am. Chem. Soc. 2021, 143, 6376―6381. Chang, X.; Zhang, J.; Peng, L.; Guo, C.* Collective synthesis of acetylenic pharmaceuticals via enantioselective Nickel/Lewis acid-catalyzed propargylic alkylation. Nat. Commum. 2021, 12, 299. Zhang, Q.; Liang, K.; Guo, C.* Asymmetric Electrochemical Arylation in the Formal Synthesis of (+)-Amurensinine. CCS Chem. 2021, 3, 338. Chang, X.; Zhang, J.; Zhang, Q.; Guo, C.* Merging Electrosynthesis and Bifunctional Squaramide Catalysis in the Asymmetric Detrifluoroacetylative Alkylation Reactions. Angew. Chem. Int. Ed. 2020, 59, 18500―18504. Peng, L.; He, Z.; Xu, X.; Guo, C.* Cooperative Ni/Cu-Catalyzed Asymmetric Propargylic Alkylation of Aldimine Esters. Angew. Chem. Int. Ed. 2020, 59, 14270―14274. Chang, X.; Zhang, Q.; Guo, C.* Asymmetric Electrochemical Transformation. Angew. Chem. Int. Ed. 2020, 59, 12612―12622. Wang, H.; Hu, Q.; Wang, M.; Guo, C.* Enantioselective [4+2] Annulation to the Concise Synthesis of Chiral Dihydrocarbazoles. iScience 2020, 23, 100840. Zhang, Q.; Chang, X.; Peng, L.; Guo, C.* Asymmetric Lewis Acid Catalyzed Electrochemical Alkylation. Angew. Chem. Int. Ed. 2019, 58, 6999―7003. Chang, X.; Zhang, Q.; Guo, C.* Switchable Smiles Rearrangement for Enantioselective O-Aryl Amination. Org. Lett. 2019, 21, 4915―4918. Wang, H.; Guo, C.* Enantioselective γ‐Addition of Pyrazole and Imidazole Heterocycles to Allenoates Catalyzed by Chiral Phosphine. Angew. Chem. Int. Ed. 2019, 58, 2854―2858. Chang, X.; Zhang, Q.; Guo. C.* Electrochemical Reductive Smiles Rearrangement for C−N Bond Formation. Org. Lett. 2019, 21, 10―13. Guo, C.*; Janssen-Müller, D.; Fleige, M.; Lerchen, A.; Daniliuc, C. G.; Glorius, F.*Mechanistic studies on a cooperative NHC organocatalysis/palladium catalysis system: uncovering significant lessons for mixed chiral Pd(NHC)(PR3) catalyst design. J. Am. Chem. Soc. 2017, 139, 4443―4451. Guo, C.; Fleige, M.; Janssen-Müller, D.; Daniliuc, C. G.; Glorius, F.* Cooperative N-heterocyclic carbene/palladium-catalyzed enantioselective umpolung annulations, J. Am. Chem. Soc. 2016, 138, 7840―7843. Guo, C.; Fleige, M.; Janssen-Müller, D.; Daniliuc, C. G.; Glorius, F. * Switchable selectivity in an NHC-catalysed dearomatizing annulation reaction, Nat. Chem. 2015, 7, 842―847.

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