Geyer, Armin - University of Marburg - Department of Chemistry

个人简介

Academic Qualifications 1985 - 1991 Chemistry studies at the Technical University of Munich, Diploma in Chemistry 1991 - 1994 Ph.D., Technical University of Munich, Thesis: “ Synthese und Strukturanalyse von Thioamidbindungen und reduzierten Amidbindungen in Peptiden“ with honors ( mit Auszeichnung) 1993 Research visit at the Centro Studio Biopolimeri in Padova, Italy 1995 –2000 Habilitation at the Faculty of Chemistry, University of Konstanz “Polyol Shapes“ 2000 venia legendi for Organic Chemistry 2000 – 2001 Privatdozent at the Faculty of Chemistry, University of Konstanz 2001 – 2003 Professor for Organic Chemistry at the Faculty of Chemistry and Pharmacy, University of Regensburg 2003 Full Professor Organic Chemistry, University of Marburg Academic Appointments 1991 - 1994 Research Assistant, Technical University of Munich (BAT IIa/2) 1994 – 1995 Research Associate (BAT IIa), University of Konstanz 1995 –2001 Researcher (C1), University of Konstanz 2001 –2003 Professor (C3), University of Regensburg 2003 Professor (C4), University of Marburg

研究领域

Synthesis, NMR Spectroscopy, and Molecular Modelling of Glycoconjugates, Peptides and Peptidomimetics - Research Geyer Group (PDF-File german)

近期论文

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Diamondoid Amino Acid-based Peptide Kinase A Inhibitors ChemMedChem, 2019, 14, 663-672 Janis Müller, Romina A. Kirschner, Jan‐Philipp Berndt, Tobias Wulsdorf, Alexander Metz, Radim Hrdina, Peter R. Schreiner, Armin Geyer, Gerhard Klebe DOI: 10.1002/cmdc.201800779 Conceptional design of self-assembling bisubstrate-like inhibitors of protein kinase a resulting in a boronic acid glutamate linkage ACS Omega 2019, 4, 775-784. Janis Müller, Romina A. Kirschner, Armin Geyer, Gerhard Klebe DOI: 10.1021/acsomega.8b02364 A set of conformationally well-definded L/D-peptide epitopes provides a serological bar code for autoantibody subtypes Plos One. 2018 13(8): e0201735 Andreas Schrimpf, Dörte Brödje, Petra Pfefferle, Armin Geyer. DOI:10.1371/joural.pone.0201735 Hinge-Type Dimerization of Proteins by a Tetracysteine Peptide of High Pairing Specificity Biochemistry, 2018, 57, 3658-3664. Andreas Schrimpf, Franziska Hempel, Aitao Li, Uwe Linne, Uwe G. Maier, Manfred T. Reetz, Armin Geyer. DOI: 10.1021/acs.biochem.8b00475 Assembly of Synthetic AMiniamyloids on Polyol Templates Beilstein J. Org. Chem. 2015, 11, 2646-2653. DOI:10.3762/bjoc.11.284 Sebastian Nils Fischer, Armin Geyer. B. Eckhardt, W. Grosse, L.-O. Essen, A. Geyer. Structural characterization of a -turn mimic within a protein-protein interface. Proc. Natl. Acad. Sci. USA 2010, 107, 18336-18341. A. Bernecker, J. Ziomkowska, S. Heitmüller, R. Wieneke, A. Geyer, C. Steinem. Formation of silica precipitates on membrane surfaces in two and three dimensions. Langmuir 2010, 26, 13422-13428. A. Bernecker, R. Wieneke, R. Riedel, M. Seibt, A. Geyer, C. Steinem. Tailored synthetic polyamines for controlled biomimetic silica formation. J. Am. Chem. Soc. 2010, 132, 1023-1031. S. Enck, F. Kopp, M. A. Marahiel, A. Geyer. The reversible macrocyclization of tyrocidine A aldehyde: a hemiaminal reminiscent of the tetrahedral intermediate of macrolactamization. Org. Biomol. Chem. 2010, 8, 559-563. S. Enck, F. Kopp, M. A. Marahiel, A. Geyer. The entropy balance of nostocyclopeptide macrocyclization analysed by NMR spectroscopy. ChemBioChem 2008, 9, 2597-2601. F. Di Pasquale, D. Fischer, D. Grohmann, T. Restle, A. Geyer, A. Marx. Opposed steric constraints in human DNA polymerase β and E. coli DNA polymerase I. J. Am. Chem. Soc. 2008, 130, 10748-10757. M. Haack, S. Enck, H. Seger, A. Geyer, A. G. Beck-Sickinger. Pyridone dipeptide backbone scan to elucidate structural properties of a flexible peptide segment. J. Am. Chem. Soc. 2008, 130, 8326-8336. R. Wieneke, S. Klein, A. Geyer, E. Loos. Structural and functional characterization of galactooligosaccharides in Nostoc commune: b-D-galactofuranosyl-(1 ->6)-[b -D-galactofuranosyl-(1-> 6)]2-b -D-1,4-anhydrogalactitol and b-(1-> 6)-galactofuranosylated homologues. Carbohydrate Research. 2007, 342, 2757-2765. N. Fiori, A. Caporale, E. Schievano, S. Mammi, A. Geyer, P. Tremmel, A. Wittelsberger, I. Woznica, M. Chorev, E. Peggion. Structure-function relationship studies of PTH(1-11) analogues containing sterically hindered dipeptide mimetics. J. Pept. Sci. 2007, 13, 504-512. M. P. Vélez, T. L. A. Verhoeven, C. Draing, S. Von Aulock, M. Pfitzenmaier, A. Geyer, I. Lambrichts, C. Grangette, B. Pot, J. Vanderleyden, S. C. J. De Keersmaecker. Functional analysis of D-alanylation of lipoteichoic acid in the probiotic strain Lactobacillus rhamnosus GG. Appl. Environ. Microbiol. 2007, 73, 3595-3604. S. Marimganti, R. Wieneke, A. Geyer, M. E. Maier. Synthesis and conformational analysis of geodiamolide analogues. Eur. J. Org. Chem., 2007, 2779-2790. D. Fischer, A. Geyer. NMR Analysis of bioprotective sugars: Sucrose and oligomeric (1->2)-a-d-glucopyranosyl-(1->2)-b-d-fructofuranosides. Top. Curr. Chem. 2007, 272, 169-185. R. Hörger, A. Geyer. A shape-persistent d,l-dipeptide building block for the assembly of rigidified oligopeptides. Org. Biomol. Chem. 2006, 4, 4491-4496.