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V. Nguyen, C. Wilson, M. Hoemberger, J. Stiller, R. Agafonov, J. English, S. Kutter, D. Theobald and Kern, Dorothee. "Evolutionary Drivers of Thermoadaptation in Enzyme Catalysis”." Science (2017). Agafonov R.V., Wilson C, Kern, Dorothee,. "Evolution and intelligent design in drug development.." Frontiers in Molecular Biosciences 2. (2016): 27. Chakrabarti KS, Agafonov RV, Pontiggia F, Otten R, Higgins MK, Schertler GF, Oprian DD, Kern, Dorothee. "Conformational Selection in a Protein-Protein Interaction Revealed by Dynamic Pathway Analysis.." Cell Reports 14. 1 (2016): 32. Eichner T, Kutter S, Labeikovsky W, Buosi V, Kern, Dorothee. "Molecular mechanism of Pin1-tau recognition and catalysis." J Mol Biol March 17. (2016). F. Pontiggia, D.V.Pachov, M.W.Clarkson, J. Villali, M.F.Hagan, V.S.Pande, Kern, Dorothee,. "Free energy landscape of activation in a signaling protein at atomic resolution." Nature Commun 15. 6 (2016): 7284. Kutter S, Eichner T, Deaconescu AM, Kern, Dorothee. "Regulation of microtubule assembly by tau and not by Pin1." J Mol BIOL March 17. (2016). C. Wilson, R. V. Agafonov, M. Hoemberger, S. Kutter, A. Zorba, J. Halpin, V. Buosi, R. Otten, D. Waterman, D. L. Theobald and D. Kern. "Using Ancient Protein Kinases to Unravel a Modern Cancer Drug’s Mechanism." Science 347. 6224 (2015): 882-6. Hass MA , Liu WM, Agafonov RV, Otten R, Phung LA, Schilder JT, Kern D, Ubbink M. "A minor conformation of a lanthanide tag on adenylate kinase characterized by paramagnetic relaxation dispersion NMR spectroscopy." J Biomol NMR 61. 2 (2015): 123-36. S.J. Kerns, R.V. Agafonov, Y.-J. Cho, F. Pontiggia, R. Otten, D.V. Pachov, L.A. Phung, P.N. Murphy, V. Thai, M.F. Hagan, T. Alber, D. Kern. "Energy landscape of Adenylate Kinase Catalysis." Nature Struct Mol Biol 22. 2 (2015): 124-31. A. Zorba, V. Buosi , S. Kutter , N. Kern , F. Pontiggia , Y.J. Cho and D.Kern. "Molecular mechanism of Aurora A kinase autophosphorylation and its allosteric activation by TPX2." Elife May 27;3:e02667.. (2014). R.V. Agafonov, C. Wilson, R. Otten, V. Buosi, D. Kern. "Energetic dissection of Gleevec’s selectivity towards human tyrosine kinases." Nature Struct Mol Biol 10. (2014): 848-53. Villali, J., Pontiggia, F., Clarkson, M.W., Hagan, M. and Kern, D.. "Evidence against the 'Y-T coupling' mechanism of activation in the response regulator NtrC." J Mol Biol 426. 7 (2014): 1554-67. Park, J.M; Hu, J.H.; Milshteyn, A.; Zhang, P.-W.; Moore, C.G. ; Park, S.; Datko, M.C.; Doming, R.D.; Reye, C.M.; Wang, X.J.; Etzkorn, F.A.; Xiao, B.; Szumlinski, K.K.; Kern, D.; Linden, D.J.; Worley, P.F. "A Prolyl-isomerase Mediates Dopamine-dependent Plasticity and Cocaine Motor Sensitization." Cell 154. 3 (2013): 637-650. Ranaghan MJ, Kumar RP, Chakrabarti KS, Buosi V, Kern D, Oprian DD.. "A Highly Conserved Cysteine of Neuronal Calcium-sensing Proteins Controls Cooperative Binding of Ca2+ to Recoverin." J Biol Chem 288. 50 (2013): 36160-7. Morrison EA, DeKoster GT, Dutta S, Vafabakhsh R, Clarkson MW, Bahl A, Kern D, Ha T, Henzler-Wildman KA.. "Antiparallel EmrE exports drugs by exchanging between asymmetric structures.." Nature 481. (2011): 45-50. Bosco DA, Eisenmesser EZ, Clarkson MW, Wolf-Watz M, Labeikovsky W, Millet O, Kern D.. "“Dissecting the Microscopic Steps of the Cyclophilin A Enzymatic Cycle on the Biological Substrate HIV Capsid by NMR.”." J. Mol. Biol. 403. 5 (2010): 723-738. Otten R, Villali J, Kern D, Mulder FA.. "“Probing Microsecond Time Scale Dynamics in Proteins by Methyl (1)H Carr-Purcell-Meiboom-Gill Relaxation Dispersion NMR Measurements. Application to Activation of the Signaling Protein NtrC(r)”.." J Am Chem Soc. 132. 47 (2010): 17004-17014. Villali, J. and Kern, Dorothee. "“Choreographing an enzyme's dance.”." Curr Opin Chem Biol. 5. 1 (2010): 636-643. Clarkson MW, Lei M, Eisenmesser EZ, Labeikovsky W, Redfield A. and Kern, Dorothee. "Mesodynamics in the SARS nucleocapsid measured by NMR field cycling." J Biomol NMR 45. 1 (2009): 217-225. Fraser, J.S., Clarkson, M.W., Degnan, S.C., Erion, R., Kern, D. Alber, T.. "Hidden alternative structures of proline isomerase essential for catalysis." Nature 462. 1 (2009): 669-673. Gardino, A.K., Villali, J., Kivenson, A., Lei, M., Liu, C.F., Steindel, P. Eisenmesser, E.Z., Labeikovsky, W. Wolf-Watz, M., Clarkson. M.W. and Kern, Dorothee. "Transient non-native bonds promote activation of a signaling protein." Cell 139. 6 (2009): 1109-1118. Lei, M., Velos, J., Gardino, A., Kivenson, A., Karplus, M. and Kern, Dorothee. "Segmented Transition Pathway of the Signaling Protein Nitrogen Regulatory Protein C." J. Mol. Biol. 392. 3 (2009): 823-836. Shim S, Yuan JP, Kim JY, Zeng W, Huang G, Milshteyn A, Kern, Dorothee, Muallem S, Ming GL, Worley PF. "Peptidyl-prolyl isomerase FKBP52 controls chemotropic guidance of neuronal growth cones via regulation of TRPC1 channel opening." Neuron 64. 1 (2009): 471-483. Gardino, A.K. and Kern D.. "¿Functional Dynamics of Response Regulators using NMR Relaxation Techniques¿." Methods in Enzym 423. (2008): :149-165.. Henzler-Wildman KA, Lei M, Thai V, Kerns SJ, Karplus M, Kern D.. "A hierarchy of timescales in protein dynamics is linked to enzyme catalysis." Nature 450. 7171 (2008): 913-916.