Tolan, Dean R. - Boston University - Department of Biology

研究领域

biochemistry, enzymology, molecular and human genetics of enzymes in sugar metabolism

近期论文

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Oppelt, SA, Coffee, EM, and Tolan, DR (2015) Aldolase-B Deficiency in Mice Phenocopies Hereditary Fructose Intolerance in Humans. Molecular Genetics and Metabolism, 114, 445-450. {PMCID-25637246] Coffee, EM and Tolan, DR (2014) Chapter 3: Gluconeogenesis, In Inborn Errors in Metabolism: From Neonatal Screening to Metabolic Pathways. Lee, B. & Scaglia, F., eds. (Oxford University Press, New York), 68-91 of 384p. [ISBN: 9780199797585] Ritterson Lew C, Tolan DR (2013) Aldolase Sequesters WASP and Affects WASP/Arp2/3-Stimulated Actin Dynamics. Journal of Cellular Biochemistry, 114, 1928-1939. Ritterson Lew C, Tolan DR (2012) Targeting of several glycolytic enzymes using RNA interference reveals aldolase affects cancer-cell proliferation through a non-glycolytic mechanism. Journal of Biological Chemistry, 287, 42554-42563. Stopa JS, Tolan DR (2011) Stabilization of the predominant hereditary fructose intolerance causing aldolase variant (A149P) with zwitterionic osmolytes. Biochemistry, 50, 663-671. Coffee EM, Tolan DR (2010) Mutations in the promoter region of the Aldolase B gene that cause Hereditary Fructose Intolerance are common among Hispanics and African-Americans. Journal of Inherited Metabolic Disease 33, 715-725. Funari VA, Voevodski K, Leyfer D, Yerkes L, Cramer D, and Tolan DR (2010) Quantitative gene-expression profiles in real time from expressed sequence tag databases. Gene Expression, 14, 321-336. Coffee EM, Yerkes L, Ewen EP, Zee T, and Tolan DR (2010). Increased prevalence of mutant null alleles that cause hereditary fructose intolerance in the American population. Journal of Inherited Metabolic Disease 33, 33-42.