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研究领域

Cardiac development and disease, muscle regeneration, muscular dystrophy, mouse developmental biology, gene regulation

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Desjardins CA, Naya FJ (2017) Antagonistic regulation of cell cycle and differentiation gene programs in neonatal cardiomyocytes by homologous MEF2 transcription factors. J Biol Chem. May 4 [Epub ahead of print]. Desjardins CA, Naya FJ (2016) The Function of the MEF2 Transcription Factor Family in Cardiac Development, Cardiogenomics, and Direct Reprogramming. J Cardiovasc Dev Dis. 3(3): 26. Clark AL, Maruyama S, Sano S, Accorsi A, Girgenrath M, Walsh K, and Naya FJ (2016) miR-410 and miR-495 are dynamically regulated in diverse cardiomyopathies and their inhibition attenuates pathological hypertrophy. PLoS One. 11(3):e0151515. Estrella NL, Clark AL, Desjardins CA, Nocco SE, Naya FJ (2015) MEF2D Deficiency in Neonatal Cardiomyocytes Triggers Cell Cycle Re-entry and Programmed Cell Death in vitro. J Biol Chem. 2015 August 20. 290(40): 24367-80. Clark AL, Naya FJ (2015) MicroRNAs in the Myocyte Enhancer Factor 2 (MEF2)-regulated Gtl2-Dio3 Noncoding RNA Locus Promote Cardiomyocyte Proliferation by Targeting the Transcriptional Coactivator Cited2. J Biol Chem. 2015 August 3. 290(38): 23162-72. Estrella NL, Desjardins CA, Nocco SE, Clark AL, Maksimenko Y, Naya FJ (2015) MEF2 transcription factors regulate distinct gene programs in mammalian skeletal muscle differentiation. J Biol Chem. 290(2): 1256-68. Estrella NL, Naya FJ (2014). Transcriptional networks regulating the costamere, sarcomere, and other cytoskeletal structures in striated muscle. Cell Mol Life Sci. 71(9): 1641-56. Snyder CM, Rice AL, Estrella NL, Held A, Kandarian SC, Naya FJ (2013) MEF2A regulates the Gtl2-Dio3 microRNA mega-cluster to modulate Wnt signaling in skeletal muscle regeneration. Development. 140(1): 31-42.

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