Fuxman Bass, Juan - Boston University

研究领域

immune regulation, gene regulatory networks, systems biology, disease mutations, inflammation, transcription factors

近期论文

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Fuxman Bass JI, Sahni N, Shrestha S, Garcia-Gonzalez A, Mori A, Bhat N, Yi S, Hill DE, Vidal M, Walhout AJ. Human Gene-Centered Transcription Factor Networks for Enhancers and Disease Variants. Cell. 2015 Apr 23;161(3): 661-73. *Sahni N, *Yi S, *Taipale M, *Fuxman Bass JI, *Coulombe-Huntington J, Yang F, Peng J, Weile J, Karras GI, Wang Y, Kovács IA, Kamburov A, Krykbaeva I, Lam MH, Tucker G, Khurana V, Sharma A, Liu YY, Yachie N, Zhong Q, Shen Y, Palagi A, San-Miguel A, Fan C, Balcha D, Dricot A, Jordan DM, Walsh JM, Shah AA, Yang X, Stoyanova AK, Leighton A, Calderwood MA, Jacob Y, Cusick ME, Salehi-Ashtiani K, Whitesell LJ, Sunyaev S, Berger B, Barabási AL, Charloteaux B, Hill DE, Hao T, Roth FP, Xia Y, Walhout AJ, Lindquist S, Vidal M. Widespread Perturbation of Disease-Specific Macromolecular Interactions in Human Genetic Disorders. Cell. 2015 Apr 23;161(3): 647-60. (*co-first author). Fuxman Bass JI, Diallo A, Nelson J, Soto JM, Myers CL, Walhout AJ. Using networks to measure similarity between genes: association index selection. Nature Methods. 2013 Dec. 10(12): 1169-76. Fuxman Bass JI, Tamburino AM, Mori A, Beittel N, Weirauch MT, Reece-Hoyes JS, Walhout AJ. Transcription factor binding to Caenorhabditis elegans first introns reveals lack of redundancy with gene promoters. Nucleic Acids Res. 2013 Sep 24. 153-62. Ritter AD, Shen Y, Fuxman Bass J, Jeyaraj S, Deplancke B, Mukhopadhyay A, Xu J, Driscoll M, Tissenbaum HA, Walhout AJ. Complex expression dynamics and robustness in C. elegans insulin networks. Genome Research. 2013 Jun;23(6): 954-65. Fuxman Bass J, Russo D, Gabelloni M, Geffner J, Giordano M, Catalano M, Zorreguieta A, Trevani A. Extracellular DNA: A Major Proinflammatory Component of P. aeruginosa Biofilms. J Immunol. 2010 Jun 1;184(11): 6386-95. Fuxman Bass J, Alvarez M, Gabelloni M, Geffner J, Vermeulen M, Amaral M, Trevani A. GM-CSF enhances a CpG-independent pathway of neutrophil activation triggered by bacterial DNA. Mol Immunol. 2008 Nov;46(1): 37-44. Fuxman Bass J, Gabelloni M, Alvarez M, Vermeulen M, Russo D, Zorreguieta A, Geffner J, Trevani A. Characterization of bacterial DNA binding to human neutrophil surface. Lab Invest. 2008 Sep;88(9): 926-37.