Beffert, Uwe - Boston University - Department of Biology

研究领域

Alzheimer’s disease, apolipoproteins, lipoprotein receptors, brain development, neuronal migration, autism, cytoskeleton

近期论文

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Dillon GM, Tyler WA, Omuro KC, Kambouris J, Tyminski C, Henry S, Haydar TF, Beffert U, Ho A (2017) CLASP2 links reelin to the cytoskeleton during neocortical development. Neuron 93, 1344-1358, March 22, 2017. PMID: 28285824. Wasser CR, Masiulis I, Durakoglugil MS, Lane-Donovan C, Xian X, Beffert U, Agarwala A, Hammer RE, Herz J. (2014) Differential splicing and glycosylation of Apoer2 alters synaptic plasticity and fear learning. Science Signaling 7(353):ra113. PMID: 25429077. Beffert U, Dillon GM, Sullivan JM, Stuart CE, Gilbert JP, Kambouris JA, Ho A (2012) Microtubule plus-end tracking protein CLASP2 regulates neuronal polarity and synaptic function. Journal of Neuroscience, 32:13906-13916. PMID: 23035100. Beffert U, Nematollah Farsian F, Masiulis I, Hammer RE, Yoon SO, Giehl KM, Herz J. ApoE receptor 2 controls neuronal survival in the adult brain. Current Biology (2006) Dec 19;16(24):2446-52. PMID: 17174920. Beffert U, Weeber EJ, Durudas A, Qiu S, Masiulis I, Sweatt JD, Li WP, Adelmann G, Frotscher M, Hammer RE, Herz J. (2005) Modulation of synaptic plasticity and memory by Reelin involves differential splicing of the lipoprotein receptor Apoer2. Neuron 47(4):567-79. PMID: 16102539. Beffert U, Weeber EJ, Morfini G, Ko J, Brady ST, Tsai LH, Sweatt JD, Herz J. (2004) Reelin and cyclin-dependent kinase 5-dependent signals cooperate in regulating neuronal migration and synaptic transmission. Journal of Neuroscience 24(8):1897-906. PMID: 14985430. Assadi AH, Zhang G, Beffert U, McNeil RS, Renfro AL, Niu S, Quattrocchi CC, Antalffy BA, Sheldon M, Armstrong DD, Wynshaw-Boris A, Herz J, D’Arcangelo G, Clark GD. Interaction of reelin signaling and Lis1 in brain development. Nature Genetics (2003) Nov;35(3):270-6. PMID: 14578885. Beffert U, Morfini G, Bock HH, Reyna H, Brady ST, Herz J. (2002) Reelin-mediated signaling locally regulates protein kinase B/Akt and glycogen synthase kinase 3beta. Journal of Biological Chemistry 277(51):49958-64. PMID: 12376533.