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研究领域

Cytoskeletal dynamics during cell migration, axon outgrowth, development of the nervous system

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Erdogan B, Ebbert P, Lowery LA. (2016) Using Xenopus laevis retinal and spinal neurons to study mechanisms of axon guidance in vivo and in vitro.Seminars in Cell and Developmental Biology, in press. Cammarata G, Bearce E, Lowery LA. (2016) Cytoskeletal social networking in the growth cone: how +TIPs mediate microtubule-actin cross-linking to drive axon outgrowth and guidance. Cytoskeleton, doi: 10.1002/cm.21271 Bearce B, Erdogan B, Lowery LA. (2015) TIPsy tour guides: How microtubule plus-end tracking proteins (+TIPS) facilitate axon guidance. Frontiers in Cellular Neuroscience. 9:241. doi: 10.3389/fncel.2015.00241. Lucaj C, Evans M, Nwagbara B, Ebbert P, Baker C, Francl A, Ruvolo S, Lowery LA. (2015) Xenopus TACC1 is a microtubule plus-end tracking protein that can regulate microtubule dynamics during embryonic development. Cytoskeleton. 72(5):225-34. Nwagbara B, Faris A, Bearce E, Erdogan B, Ebbert P, Evans M, Rutherford E, Enzenbacher T, Lowery LA. (2014) TACC3 is a microtubule plus-end tracking protein that promotes axon elongation and also regulates microtubule plus-end dynamics in multiple embryonic cell types. Molecular Biology of the Cell, Epub ahead of print. Stout A, D'Amico S, Enzenbacher T, Ebbert P, Lowery LA. (2014) Using plusTipTracker software to measure microtubule dynamics in Xenopus laevis growth cones. Journal of Visualized Experiments (91) e52138. Lowery LA. (2014) Axon guidance: FLRTing promotes attraction. Current Biology Volume 24, Issue 5, R198-R200. Lowery LA, Stout A, Faris AE, Ding L, Baird MA, Davidson MW, Danuser G, Van Vactor D. (2013) Growth cone-specific functions of XMAP215 in restricting microtubule dynamics and promoting axonal outgrowth. Neural Dev Dec 1;8(1):22. Long JB, Bagonis M, Lowery LA, Lee H, Danuser G, Van Vactor D. (2013) Multiparametric analysis of CLASP-interacting protein functions during interphase microtubule dynamics. Mol Cell Biol 33(8):1528-45. Lowery LA, Faris AE, Stout A, Van Vactor D. (2012) Neural explant cultures from Xenopus laevis. Journal of Visualized Experiments (68):e4232. Lowery LA, Lee H, Lu C, Murphy R, Obar RA, Zhai B, Schedl M, Van Vactor D, Zhan Y. (2010) Parallel genetic and proteomic screens identify Msps as a CLASP-Abl pathway interactor in Drosophila. Genetics 185:1311-25. Lowery LA and Van Vactor D. (2009) The trip of the tip: understanding the growth cone machinery. Nature Reviews Mol Cell Biol 10:332-43. Lowery LA, Sive H. (2009) Totally tubular: the mystery behind function and origin of the brain ventricular system. Bioessays 31(4):446-58. Lowery LA, De Rienzo G, Gutzman J, Sive H. (2009) Characterization and classification of zebrafish brain morphology mutants. Anatomical Record 292(1):94-106. Lowery LA, Rubin J, Sive H. (2007) wis/sfpq is required for cell survival and neuronal development in the zebrafish. Developmental Dynamics 236(5):1347-57. Lowery LA and Sive H. (2005) Initial formation of zebrafish brain ventricles occurs independently of circulation and requires the nagie oko and snakehead/ atp1a1a.1 gene products. Development 132(9):2057-67. Lowery LA and Sive H. (2004) Strategies of vertebrate neurulation and a re-evaluation of teleost neural tube formation. Mechanisms of Development 121(10):1189-97.

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