Hake, Laura E. - Boston College - Department of Biology

研究领域

Translational regulation and signal transduction during meiosis and in early animal development.

近期论文

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Keady, B.T., Kuo, P., Martínez, S.E., Yuan, L., and Hake, L.E. 2007. MAPK interacts with XGef and is required for CPEB activation during meiosis in Xenopus oocytes. Journal of Cell Science 120(6): 1093–1103. Martinez, S., Yuan, L., Lacza, C., Ransom, H., Mahon, G. M., Whitehead, I. P. and Hake, L. E. 2005. XGef mediates early phosphorylation of CPEB during Xenopus oocyte meiotic maturation. Molecular Biology of the Cell 16: 1152–64. Reverte, C. G., Yuan, L., Keady, B. T., Attfield, K. R., Mahon, G. M., Freeman, B., Whitehead, I. P., and Hake, L. E. 2003. XGef is a CPEB-interacting protein involved in Xenopus oocyte maturation. Developmental Biology 255: 383–398. Keady, B.T., Attfield, K. R., and Hake, L. E. 2002. Differential processing of the Xenopus ATP(CTP):tRNA nucleotidyltransferase mRNA. Biochemical and Biophysical Research Communications 297: 573–580. Reverte, C. G., Ahearn, M. D., and Hake, L. E. 2001. Stockpiling and degradation of CPEB during Xenopus oogenesis and oocyte maturation. Developmental Biology 231: 447–458. Mendez, R., Hake, L. E., Andresson, T., Littlepage, L. E. Ruderman, J. V., and Richter, J. D. 2000. Phosphorylation of CPEB by Eg2 regulates c-mos mRNA translation. Nature 404: 302–307. Chavous, D. A., Hake, L. E., Lynch, R. P. and O'Connor, C. M. 2000. Translation of a unique transcript for protein isoaspartyl methyltransferase in haploid spermatids: Implications for protein storage and repair. Molecular Reproduction and Development 56: 1–6. Walker, J., Minshall, N., Hake, L. E., Richter, J., and Standart, N. 1999. The clam 3' UTR masking element-binding protein p82 is member of the CPEB family. RNA 5: 14–26. Hake, L. E., Mendez, R., and Richter, J. D. 1998. Specificity of RNA binding by CPEB: Requirement for RRMs and a novel zinc finger. Molecular and Cellular Biology 18: 685–693. Hake, L. E., and Richter, J. D. 1997. Translational regulation of maternal mRNAs. BBA Reviews on Cancer 133: M31–M38. Stebbins-Boaz, B., Hake, L. E., and Richter, J. D. 1996. CPEB controls the cytoplasmic polyadenylation of cyclin, cdk2 and c-mos mRNAs and is necessary for oocyte maturation in Xenopus. EMBO Journal 15: 2582–2592. Hake, L. E., and Richter, J. D. 1994. CPEB is a specificity factor that mediates cytoplasmic polyadenylation during Xenopus oocyte maturation. Cell 79: 617–627. Hake, L. E., and Hecht, N. B. 1993. Utilization of an alternative transcription initiation site of somatic cytochrome c in the mouse produces a testis-specific 1.7 kb cytochrome c mRNA. Journal of Biological Chemistry 268: 4788–4797.