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个人简介

Dr. Ilan Wittstein is a cardiologist and the foremost expert in “broken heart syndrome,” also known as stress cardiomyopathy or takotsubo cardiomyopathy. His 2005 article in the New England Journal of Medicine explaining the mechanisms of short-term heart failure after extreme stress introduced this syndrome to the global medical community. Dr. Wittstein has lectured extensively on stress cardiomyopathy, both nationally and internationally, and has appeared in scores of major media stories on national TV and radio networks, in international documentaries, newspapers, magazines and websites. Time Magazine called stress cardiomyopathy one of 2005’s most important medical discoveries. As a result of Dr. Wittstein’s work, Johns Hopkins Hospital has become a referral center for patients diagnosed with this condition. Dr. Wittstein received his undergraduate degree from Wesleyan University in Connecticut, then completed medical school, residency, and two cardiology fellowships at the Johns Hopkins University School of Medicine. He is an assistant professor of medicine and gives regular lectures and seminars on topics of coronary care. Dr. Wittstein also serves as a peer reviewer for over 20 journals including Lancet, Nature Medicine, New England Journal of Medicine, Journal of the American College of Cardiology and European Heart Journal. MD, Johns Hopkins University School of Medicine (1990)

研究领域

Effect of emotional and psychological stress on cardiac function; Stress Cardiomyopathy

近期论文

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Ilan S. Wittstein; David R. Thiemann; Joao A.C. Lima; Kenneth L. Baughman; Steven P. Schulman; Gary Gerstenblith; Katherine C. Wu; Jeffrey J. Rade; Trinity J. Bivalacqua; Hunter C. Champion. Neurohumoral features of myocardial stunning due to sudden emotional stress. New England Journal of Medicine. 2005;352(6):539-548. Daniel J Brotman; Sherita H Golden; Ilan S Wittstein. The cardiovascular toll of stress. Lancet. 2007;370(9592):1089-1100. Jacob Abraham; James O. Mudd; Navin Kapur; Kelly Klein; Hunter C. Champion; Ilan S. Wittstein. Stress Cardiomyopathy After Intravenous Administration of Catecholamines and Beta-Receptor Agonists. Journal of the American College of Cardiology. 2009;53(15):1320-1325. David B. Bekelman; Edward P. Havranek; Diane M. Becker; Jean S. Kutner; Pamela N. Peterson; Ilan S. Wittstein; Sheldon H. Gottlieb; Traci E. Yamashita; Diane L. Fairclough; Sydney M. Dy. Symptoms, Depression, and Quality of Life in Patients With Heart Failure. Journal of Cardiac Failure. 2007;13(8):643-648. S. Laowattana; S.L. Zeger; J.A.C. Lima; S.N. Goodman; I.S. Wittstein; S.M. Oppenheimer. Left insular stroke is associated with adverse cardiac outcome. Neurology. 2006;66(4):477-483. David B. Bekelman; Sydney M. Dy; Diane M. Becker; Ilan S. Wittstein; Danetta E. Hendricks; Traci E. Yamashita; Sheldon H. Gottlieb. Spiritual well-being and depression in patients with heart failure. Journal of General Internal Medicine. 2007;22(4):470-477. Ryan J Tedford; Anna R Hemnes; Stuart D Russell; Ilan S Wittstein; Mobusher Mahmud; Ari L Zaiman; Stephen C Mathai; David R Thiemann; Paul M Hassoun; Reda E Girgis; et al. PDE5A inhibitor treatment of persistent pulmonary hypertension after mechanical circulatory support. Circulation. Heart failure. 2008;1(4):213-219. Bettina Heidecker; Edward K. Kasper; Ilan S. Wittstein; Hunter C. Champion; Elayne Breton; Stuart D. Russell; Michelle M. Kittleson; Kenneth L. Baughman; Joshua M. Hare. Transcriptomic biomarkers for individual risk assessment in new-onset heart failure. Circulation. 2008;118(3):238-246. Xinqi Peng; Fabio A. Recchia; Barry J. Byrne; Ilan S. Wittstein; Roy C. Ziegelstein; David A. Kass. In vitro system to study realistic pulsatile flow and stretch signaling in cultured vascular cells. American Journal of Physiology - Cell Physiology. 2000;279(3 48-3):C797-C805. Ilan S. Wittstein. Stress cardiomyopathy: A syndrome of catecholamine-mediated myocardial stunning? Cellular and Molecular Neurobiology. 2012;32(5):847-857.

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