Tampakakis, Emmanouil - Johns Hopkins University

个人简介

Dr. Emmanouil Tampakakis is an instructor in the Department of Medicine at Johns Hopkins University School of Medicine as well as an attending physician at Johns Hopkins Hospital. His research at the Chulan Kwon’s Laboratory of Heart Development and Stem Cell Biology focuses on understanding the biology and regenerative potential of cardiac progenitor cells, using human induced pluripotent stem cells for modeling cardiomyopathies and deciphering the mechanisms of cardiac maturation. Dr. Tampakakis also holds a cardiology fellowship at Johns Hopkins Hospital. Dr. Tampakakis received his undergraduate degree and M.D. from the University of Crete. He completed an internal medicine residency at Boston University Medical Center. Prior to joining Johns Hopkins in 2012, Dr. Tampakakis was a research fellow in Dr. J. Vita’s laboratory of Vascular Biology at Boston University School of Medicine. Dr. Tampakakis is the recipient of the Mid Atlantic Capital Cardiology Symposium, Young Investigator Award and was most recently honored with an AHA Scientific Sessions Travel Award and has been a Northwestern Young Investigator Forum Finalist.

研究领域

查看导师最新文章（温馨提示：请注意重名现象，建议点开原文通过作者单位确认）

Research Fellow in Dr. C. Kwon’s Laboratory of Developmental and Stem Cell Biology. Heart malformation is the most frequent form of human birth defects, and cardiovascular disease remains the leading cause of death worldwide. The limited regenerative capacity of the heart is a major factor in the morbidity and mortality rates. Cardiovascular progenitor cells hold tremendous therapeutic potential due to their unique ability to expand and differentiate into various heart cell types. The C. Kwon laboratory focuses on understanding the biology and regenerative potential of multi-potent cardiac progenitor cells by deciphering the molecular and cellular mechanisms that control their induction, maintenance and differentiation. We are also investigating how cardiac muscles undergo maturation. We developed several novel approaches to deconstruct the mechanisms, including the use of animal models and pluripotent stem cell systems. We expect this knowledge will help us better understand heart disease and will be instrumental for stem-cell-based disease modeling and interventions for of heart repair.