Rouf, Rosanne - Johns Hopkins University

个人简介

Dr. Rosanne Rouf is a cardiologist with expertise in the medical care of heart failure and heart transplant patients. Her research interests include the role of gene expression in heart failure and in heart defects related to Marfan and Loeys-Deitz syndromes. Dr. Rouf received her undergraduate and master’s degrees in electrical engineering and computer science from the Massachusetts Institute of Technology. She graduated from the Duke University School of Medicine, and completed her residency at the Tufts Medical Center. Dr. Rouf pursued fellowships at Tufts and Johns Hopkins, joining the faculty of the Johns Hopkins School of Medicine in 2011. MD, Duke University School of Medicine (2002)

研究领域

The role of matricellular proteins in modulating cardiac fibrosis and heart failure

近期论文

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Gallo EM, Loch DC, Habashi JP, Calderon JF, Chen Y, Bedja D, van Erp C, Gerber EE, Parker SJ, Sauls K, Judge DP, Cooke SK, Lindsay ME, Rouf R, Myers L, Ap Rhys CM, Kent KC, Norris RA, Huso DL, Dietz HC. Angiotensin II-dependent TGF-β signaling contributes to Loeys-Dietz syndrome vascular pathogenesis. J Clin Invest. 2014 Jan 2;124(1):448-60. Gould RA, Sinha R, Aziz H, Rouf R, Dietz HC 3rd, Judge DP, Butcher J. Multi-scale biomechanical remodeling in aging and genetic mutant murine mitral valve leaflets: insights into Marfan syndrome. PLoS One. September 11, 2012; 7(9):e44639. Wei H, Bedja D, Koitabashi N, Xing D, Chen J, Fox-Talbot K, Rouf R, Chen S, Steenbergen C, Harmon JW, Dietz HC, Gabrielson KL, Kass DA, Semenza GL. Endothelial expression of hypoxia inducible factor 1 protects the murine heart and aorta from pressure overload by suppression of TGFb signaling. Proceedings of the National Academy of Sciences. March 8, 2012. Judge DP, Rouf R, Habashi J, Dietz HC. Mitral valve disease in Marfan syndrome and relate disorders. Journal of Cardiovascular Translational Research. August 25, 2011. Judge DP, Rouf R. Use of genetics in the clinical evaluation and management of heart failure. Current Treatment Options in Cardiovascular Medicine. December 2010; 12(6):566-77. Blaha MJ, Bansal S, Rouf R, Golden SH, DeFilippis AP, Blumenthal RS. A practical ‘ABCDE' approach to treating the metabolic syndrome. Mayo Clinic Proceedings. August 2008; 83(8):932-41. Rouf R, Greytak S, Wooten EC, Wu J, Boltax J, Picard M, Dillman WH, Patten RD, Huggins GS. Increased FOG-2 in failing myocardium disrupts thyroid hormone-dependent SERCA2 gene transcription. Circulation Research. August 29, 2008;102(5):493-501. Mudd JO, Borlaug BA, Johnston PV, Kral BG, Rouf R, Blumenthal RS, Kwiterovich PO, Jr. BeyondLDL Cholesterol—Defining the role of LDL heterogeneity in coronary artery disease. Journal of American College of Cardiology. October 30, 2007; 50:1735-1741.