个人简介

Dr. Howard Levy is an assistant professor of medicine at the Johns Hopkins University School of Medicine. His areas of clinical expertise include routine primary care, pharmacogenetics, cancer genetics, clinical genetics and Ehlers Danlos syndrome. Dr. Levy received his undergraduate degree from the University of Maryland. He earned his Ph.D. and M.D. from the University of Maryland at Baltimore. He completed his residency at Boston Medical Center and performed a fellowship in genetics at the National Institutes of Health. His research interests include genetics education, heritable disorders of connective tissue, electronic health records (EHRs) and EHR patient portals.

研究领域

Genetics Education; Heritable Disorders of Connective Tissue

Dr. Levy’s research focuses on the integration of genetics into primary care, education of non-geneticist providers about genetics, the natural history and management of Ehlers Danlos syndrome and related disorders of connective tissue, and patient-centered use of electronic health records and patient portals.  

近期论文

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Botkin JR, Belmont JW, Berg JS, Berkman BE, Bombard Y, Holm IA, Levy HP, Ormond KE, Saal HM, Spinner NB, Wilfond BS, McInerney JD. "Points to consider: ethical, legal, and psychosocial implications of genetic testing in children and adolescents." Am J Hum Genet. 2015 Jul 2;97(1):6-21. doi: 10.1016/j.ajhg.2015.05.022. Review. Turriff A, Levy HP, Biesecker B. "Factors associated with adaptation to Klinefelter syndrome: the experience of adolescents and adults." Patient Educ Couns. 2015 Jan;98(1):90-5. doi: 10.1016/j.pec.2014.08.012. Epub 2014 Aug 27. Cohen JS, Levy HP, Sloan J, Dariotis J, Biesecker BB. "Depression among adults with neurofibromatosis type 1: prevalence and impact on quality of life." Clin Genet. 2014 Dec 23. doi: 10.1111/cge.12551. [Epub ahead of print] Ramos EM, Din-Lovinescu C, Berg JS, Brooks LD, Duncanson A, Dunn M, Good P, Hubbard TJ, Jarvik GP, O'Donnell C, Sherry ST, Aronson N, Biesecker LG, Blumberg B, Calonge N, Colhoun HM, Epstein RS, Flicek P, Gordon ES, Green ED, Green RC, Hurles M, Kawamoto K, Knaus W, Ledbetter DH, Levy HP, Lyon E, Maglott D, McLeod HL, Rahman N, Randhawa G, Wicklund C, Manolio TA, Chisholm RL, Williams MS. "Characterizing genetic variants for clinical action." Am J Med Genet C Semin Med Genet. 2014 Mar;166C(1):93-104. doi: 10.1002/ajmg.c.31386. Epub 2014 Mar 13. Lindsay ME, Schepers D, Bolar NA, Doyle JJ, Gallo E, Fert-Bober J, Kempers MJ, Fishman EK, Chen Y, Myers L, Bjeda D, Oswald G, Elias AF, Levy HP, Anderlid BM, Yang MH, Bongers EM, Timmermans J, Braverman AC, Canham N, Mortier GR, Brunner HG, Byers PH, Van Eyk J, Van Laer L, Dietz HC, Loeys BL. "Loss-of-function mutations in TGFB2 cause a syndromic presentation of thoracic aortic aneurysm." Nat Genet. 2012 Jul 8;44(8):922-7. doi: 10.1038/ng.2349. doi: 10.1038/ng.2349. Rajan R, Benke JR, Kline AD, Levy HP, Kimball A, Mettel TL, Boss EF, Ishman SL. "Insomnia in Cornelia de Lange syndrome." Int J Pediatr Otorhinolaryngol. 2012 Jul;76(7):972-5. doi: 10.1016/j.ijporl.2012.03.008. Epub 2012 Apr 1. Lindsay ME, Schepers D, Bolar NA, Doyle JJ, Gallo E, Fert-Bober J, Kempers MJ, Fishman EK, Chen Y, Myers L, Bjeda D, Oswald G, Elias AF, Levy HP, Anderlid BM, Yang MH, Bongers EM, Timmermans J, Braverman AC, Canham N, Mortier GR, Brunner HG, Byers PH, Van Eyk J, Van Laer L, Dietz HC, Loeys BL. Loss-of-function mutations in TGFB2 cause a syndromic presentation of thoracic aortic aneurysm. Nat Genet. 2012 Jul 8;44(8):922-7. doi: 10.1038/ng.2349. PMID: 22772368 Rajan R, Benke JR, Kline AD, Levy HP, Kimball A, Mettel TL, Boss EF, Ishman SL. Insomnia in Cornelia de Lange syndrome. Int J Pediatr Otorhinolaryngol. 2012 Jul;76(7):972-5. doi: 10.1016/j.ijporl.2012.03.008. Epub 2012 Apr 13. PMID: 22503448 Masys DR, Jarvik GP, Abernethy NF, Anderson NR, Papanicolaou GJ, Paltoo DN, Hoffman MA, Kohane IS, Levy HP. Technical desiderata for the integration of genomic data into Electronic Health Records. J Biomed Inform. 2012 Jun;45(3):419-22. doi: 10.1016/j.jbi.2011.12.005. Epub 2011 Dec 27. PMID: 22223081 Turriff A, Levy HP, Biesecker B. Prevalence and psychosocial correlates of depressive symptoms among adolescents and adults with Klinefelter syndrome. Genet Med. 2011 Nov;13(11):966-72. doi: 10.1097/GIM.0b013e3182227576. PMID: 21799429 Butrick M, Roter D, Kaphingst K, Erby LH, Haywood C Jr, Beach MC, Levy HP. Patient reactions to personalized medicine vignettes: an experimental design. Genet Med. 2011 May;13(5):421-8. doi: 10.1097/GIM.0b013e3182056133. PMID: 21270639