Klag, Michael - Johns Hopkins University

个人简介

Dr. Michael J. Klag is a professor of medicine at the Johns Hopkins University School of Medicine. He holds joint appointments in epidemiology and in health policy and management at the Johns Hopkins Bloomberg School of Public Health. His areas of clinical expertise include general internal medicine. Dr. Klag serves as the dean of the Johns Hopkins Bloomberg School of Public Health. He is an internist and epidemiologist who earned his medical degree at the University of Pennsylvania and his master’s in public health degree from the Johns Hopkins School of Hygiene and Public Health. For eight years, he was director of the Division of General Internal Medicine and was the first vice dean for clinical investigation at the Johns Hopkins School of Medicine, where he instituted new policies and procedures for oversight of human subject research. Dr. Klag is a world-renowned kidney disease epidemiologist whose scientific contributions have been in the prevention and epidemiology of kidney disease, hypertension and cardiovascular disease. He was one of the earliest investigators to apply epidemiologic methods to the study of kidney disease. In doing so, he and his collaborators were able to first determine that the U.S. was in the midst of an epidemic of end-stage kidney disease, determine the incidence of kidney disease, and publish the risk of developing kidney disease associated with blood pressure, diabetes, race, socioeconomic status and other factors. These findings are considered landmark contributions. He directs one of the longest running longitudinal studies in existence, the Precursors Study, which began in 1946. Results of that study demonstrated that serum cholesterol measured at age 22 years predicts cardiovascular disease in midlife. This work had a profound impact on the policy related to cholesterol screening in young people. He has also shown that health behaviors and other factors lead to the development of hypertension, and that differences in risk of hypertension in urban and non-urban societies can be explained by differences in health behaviors. Dr. Klag is the author of more than 200 publications and was the Editor-in-Chief of the Johns Hopkins Family Health Book.

研究领域

Hypertension; Renal failure; Precursors Study; Kidney disease; Cardiovascular; Epidemiology; Genetic markers; Health policy and management

近期论文

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Astor BC, Eustace JA, Klag MJ, Powe NR, Longenecker JC, Fink NE, Marcovina SM, Coresh J. "Race-specific association of lipoprotein(a) with vascular access interventions in hemodialysis patients: The CHOICE Study." Kidn Internatl. 2002;61(3):1115-1123 Berenholtz SM, Pronovost PJ, Mullany D, Garrett E, Ness PM, Dorman T, Klag MJ. "Predictors of transfusion for spinal surgery in Maryland, 1997-2000." Transfusion. 2002;42:183-9 Houston TK, Meoni LA, Ford DE, Brancati FL, Cooper LA, Levine DM, Liang K-Y, Klag MJ. "Sports ability in young men and incidence of cardiovascular disease." Am J Medicine. 2002;112:689-695. Chang PP, Ford DE, Meoni LA, Wang N-Y, Klag MJ. "Anger in young men and subsequent premature cardiovascular disease: The Precursors Study." Arch Intern Med. 2002;162:901-906. Klag MJ, Wang NY, Meoni LA, Brancati FL, Cooper L, Liang KY, Young JH, Ford DE. Coffee Intake and Risk of Hypertension: The Johns Hopkins Precursors Study. Arch Intern Med 2002;162:657-662.