Gaydos, Charlotte - Johns Hopkins University

个人简介

Dr. Charlotte A. Gaydos is a Professor in the Division of Infectious Diseases, Department of Medicine of the Johns Hopkins University School of Medicine and has joint appointments in the Emergency Medicine Department and Epidemiology and Population, Family and Reproductive Health at the Johns Hopkins Bloomberg School of Public Health, and is a member of the Johns Hopkins University Center for Global Health. She received her B.S. in medical technology and her M.S. in medical microbiology from West Virginia University. Her MPH and DrPH in Immunology and Infectious Diseases were received from Johns Hopkins University School of Public Health. Dr. Gaydos is the Director of the Johns Hopkins University International STI, Respiratory Diseases, and Biothreat Research Laboratory. She has 45 years laboratory expertise in microbiology, has authored 27 book chapters, over 400 research articles, and over 600 abstracts and oral presentations. Dr. Gaydos has conducted multiple FDA clinical trials for new diagnostics for STIs and respiratory pathogens. She has extensive laboratory experience in the development and evaluation of molecular amplification testing techniques for respiratory, urogenital, and biothreat specimens, as well as epidemiology expertise. Dr. Gaydos has performed original research developing DNA amplification tests for Chlamydia trachomatis, C. pneumoniae, C. psittaci, Trichomonas vaginalis, N. gonorrhoeae, Mycoplasma genitalium, and the agents of genital ulcer disease. She performed sentinel STI studies in schools and in male and female military recruits. Her Internet recruitment of at-home, self-collected samples for STI screening has been an effective out-reach program, demonstrating an acceptable method for reaching women and men who may not attend clinics. Her CAP accredited, CLIA certified, State of Maryland licensed laboratory is a Core Diagnostic/Reference Laboratory for international studies of sexually transmitted infections, respiratory diseases, and trachoma. She was a co-investigator for 10 years for the Mid-Atlantic Regional Center of Excellence (MARCE) for emerging infectious diseases. She is the Principal Investigator of this NIH/NIBIB Center U54 grant to develop point-of-care tests for STIs, as well as a co-investigator for a new NIH Center of Excellence in Influenza Research and Surveillance (CEIRS). Dr. Gaydos is the Director of the North American Branch for the International Union Against Sexually Transmitted Infections (IUSTI). She serves on the editorial board of the Sexually Transmitted Diseases journal and the executive committees of the American Sexually Transmitted Diseases Association (ASTDA) and the International Society for Sexually Transmitted Diseases Research (ISSTDR). She also serves on the National Chlamydia Laboratory Committee, sponsored by the Centers for Disease Control and Prevention (CDC) and on CDC expert panels for laboratory diagnosis of STDs.

研究领域

Mycoplasma genitalium; Neissseria gonorrhoeae; C. psittaci. Trichomonas vaginalis; C. pneumoniae; Chlamydia trachomatis

近期论文

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Gaydos CA. Barnes MR, Quinn N, Jett-Goheen, Hsieh Y-H. Trichomonas vaginalis infection in men who submit self-collected penile swabs after internet recruitment. Sex Transmit Dis. (epub ahead of print January 26, 2013 as 10.1136/sextrans-2012-050946). PMID: 23354525 Jeng K, Hardick J, Rothman R, Yang S, Won H, Peterson S, Hsieh Y-H, Masek B, Carroll K, Gaydos CA. RT-PCR/ESI-MS for Rapid Detection of Biothreat and Common Respiratory Pathogens. J Clin Microbiol (in press). Gaydos CA, Van Der Pol B, Jett-Goheen M, Barnes M, Quinn N, Clark C, Daniel GE, Dixon PB, Hook III EW, CT/NG Study Group. Performance of the Cepheid CT/NG Xpert Rapid PCR Test for the Detection of Chlamydia trachomatis and Neisseria gonorrhoeae. J Clin Microbiol 51:1666-1672, 2013. PMCID: PMC3716060 Gaydos CA, Solis M, Hsieh Y-H, Jett-Goheen M, Nour S, Rothman R. Use of Tablet-Based Kiosks in the Emergency Department to Guide Patient HIV Self-Testing with a Point-of-Care Oral Fluid Test. Inter J STD Aids. DOI: 10.1177/0956462413487321 Pearce DM, Styles DN, Hardick JP, Gaydos CA. A new rapid molecular point-of-care assay for Trichomonas vaginalis: preliminary performance data. Sex Transmit Dis (in press) April 20, 2013 as 10.1136/sextrans-2012-051000. Murillo L, Hardick J, Jeng K, Gaydos CA. Evaluation of the Pan Influenza detection kit utilizing the PLEX-ID and influenza samples from the 2011 respiratory season. J Vir Methods 193:173-176, 2013 Melendez JH, Huppert J, Jett-Goheen, Hesse E, Quinn N, Gaydos CA, Geddes CD. Blinded Evaluation of the Microwave-Accelerated Metal-Enhanced Fluorescence (MAMEF) Ultra-Rapid and Sensitive Chlamydia Trachomatis Test Using Clinical Samples. J Clin Microbiol (in press) Gaydos CA, Barnes M, Jett-Goheen M, Quinn N, whittel P, Hogan T, Hsieh Y_h. Characteristics and predictors of women who obtain rescreening for sexually transmitted infections using www.iwantthekit.org screening program. Internat J STD & AIDS. online July 15, 2013 DOI: 10.1177/0956462483252 Tang YW, Lowery KS, Valsamakis A, Schaefer VC, Chappell JD, White-Abell J, Quinn CD, Li H, Washington CA, Cromwell J, Giamanco CM, Forman M, Holden J, Rothman RE, Parker ML, Ortenberg EV, Zhang L, Lin YL, Gaydos CA. Clinical Accuracy of a PLEX-ID Flu Device for Simultaneous Detection and Identification of Influenza Viruses A and B. J Clin Microbiol. 51:40-45, 2013. PMCID: PMC3536229