个人简介

Dr. Arturo Casadevall is a professor of medicine at the Johns Hopkins School of Medicine. He holds a joint appointment in molecular microbiology and immunology at the Johns Hopkins Bloomberg School of Public Health. His research focuses on how microbes cause disease and how the immune system defends itself. Dr. Casadevall serves as chair of the W. Harry Feinstone Department of Molecular Microbiology and Immunology at the Johns Hopkins Bloomberg School of Public Health. He received his M.S., Ph.D. and M.D. from New York University. Prior to joining Johns Hopkins, he served as director of the Center for Immunological Sciences at the Albert Einstein College of Medicine. His team is currently engaged in understanding how hosts defend against the fungus Cryptococcus neoformans. Dr. Casadevall’s work has been recognized with numerous awards, including the American Society for Microbiology Founders Distinguished Service Award, the National Institutes of Health Merit Award and the Rhoda Benham Award from Medical Mycology Society of America.

研究领域

Molecular microbiology and immunology; Pathogenic microbes; Cryptococcus neoformans; Cryptococcosis; Anthrax; Bacillus anthracis; Mycobacterium tuberculosis; Vaccines

Dr. Casadevall is a globally known expert in humoral immunity, molecular biology, virulence and cryptococcosis. The goal of his research is to protect people from harm caused by new pathogens and resistant organisms, and by compromised immune systems resulting from HIV, cancer therapy treatments and other causes.

近期论文

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Casadevall A, Pirofski LA. "What is a host? Incorporating themicrobiota into the damage-response framework." Infect Immun. 2015 Jan;83(1):2-7. doi: 10.1128/IAI.02627-14. Epub 2014 Nov 10. Fang FC, Casadevall A. "Competitive science: Is competition ruining science." Infect Immun. 2015 Jan 20. pii: IAI.02939-14. Achkar JM, Chan J, Casadevall A. "B cells and antiboides in the defense against Mycobacterium tuberculosis infection." Immunol Rev. Mar;264(1):167-81. doi: 10.1111/imr.12276. Coelho C, Oliveira Souza AC, Derengowski L, de Leon-Rodriguez C, Wang B, Leon-RiveraR, Bocca, AL, Gonçalves T, Casadevall A. "Macrophage mitochondrial and stress response to ingestion of Cryptococcus neoformans." J. Immunol. Mar 1;194(5):2345-57. doi: 10.4049/jimmunol.1402350. Epub 2015 Feb 2. Duprex WP, Casadevall A. "Falling down the rabbit hole: aTRIP toward lexiconic precision in the 'gain-of-function' debate." Mbio. pii: e02421-14. doi: 10.1128/mBio.02421-14. Imperiale MJ, Casadevall A. "Vagueness and costs of the pause on gain-of-function (GOF) experiments on pathogens with pandemic potential, including influenza virus." Mbio. pii: e02292-14. doi: 10.1128/mBio.02292-14.